A newly-conducted study has discovered that going to bed between 10pm and 11pm reduces the risk of developing heart disease.
If you ever needed an excuse for an early night, this is it.
The study – which was written by Dr David Plans of the University of Exeter, and published in European Heart Journal – Digital Health, a journal of the European Society of Cardiology (ESC) – found that compared to falling asleep between 10pm and 10.59pm, there was a 12% greater risk of developing cardiovascular diseases for 11pm to 11.59 pm, and a 24% increased risk for falling asleep before 10pm.
There was also a 25% higher risk of cardiovascular disease associated with falling asleep at midnight or later.
The study included 88,026 people in the UK Biobank study, recruited between 2006 and 2010, with the average age of study participants being 61 years.
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Participants were aged between 43 and 79 years old, with 58% women.
“The body has a 24-hour internal clock, called circadian rhythm, that helps regulate physical and mental functioning,” Dr David Plans explained.
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“While we cannot conclude causation from our study, the results suggest that early or late bedtimes may be more likely to disrupt the body clock, with adverse consequences for cardiovascular health.”
The study included 88,026 people in the UK Biobank study, recruited between 2006 and 2010 / Credit: Flickr
Not only that, but a further analysis by sex found that the increased cardiovascular risk was also stronger in women.
Before the study, participants were required to complete demographic, lifestyle, health, and, physical assessments and questionnaires, and then researchers collected data on sleep onset and waking up time over seven days using a device worn on the wrist.
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Participants were then followed up for a new diagnosis of cardiovascular disease – which was defined as a heart attack, heart failure, chronic ischaemic heart disease, stroke, and transient ischaemic attack – and during an average follow-up of 5.7 years, 3,172 participants (3.6%) developed cardiovascular disease, according to the study.
The study ultimately found that this diagnosis was the highest in those with bed times at midnight or later, and the lowest in those with sleep onset from 10pm to 10.59 pm.
Dr David Plans admitted that the reasons for the observed stronger association between sleep onset and cardiovascular disease in women is unclear, but concluded that: “While the findings do not show causality, sleep timing has emerged as a potential cardiac risk factor – independent of other risk factors and sleep characteristics.”
“It’s important to remember that this study can only show an association and can’t prove cause and effect,” added Regina Giblin – Senior Cardiac Nurse at the British Heart Foundation.
Featured Image – Pixabay
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Groundbreaking new ‘rapid’ jab to treat 14 different cancer types now available on NHS
Emily Sergeant
A groundbreaking new ‘rapid’ cancer jab that can be administered in just 60 seconds is now available on the NHS.
It’s hoped that tens of thousands of patients on the NHS could benefit from the new immunotherapy jab – which is an injectable form of pembrolizumab (Keytruda) – as it can slash the time the treatment takes by up to 90%, helping people spend less time in hospital while also improving the health service’s productivity.
The jab can be used to treat 14 different types of cancer, including lung, breast, head and neck, and cervical cancers.
Put simply, it works by triggering immune cells to recognise and kill cancer cells.
The new under-the-skin injection replaces an intravenous (IV) infusion – which can take up to two hours in total, per session – sparing patients ‘unnecessary’ time in treatment units and freeing up capacity for clinicians to see and treat more people.
Tens of thousands of patients could benefit from a 'rapid' immunotherapy jab for over a dozen cancers.
Given in just minutes, the new jab will cut treatment time, help patients spend less time in hospital – and boost NHS productivity.
The treatment will be given every three weeks as a one-minute injection, or every six weeks as a two-minute injection, depending on an individual’s cancer type.
Currently, around 14,000 patients start pembrolizumab therapy each year in England, and most are now expected to benefit from this more-convenient treatment.
Speaking on the rollout of the new jab this week, Professor Peter Johnson, who is the NHS National Clinical Director for Cancer, said: “This immunotherapy offers a lifeline for thousands of patients and it’s fantastic that this new rapid jab can now take just a minute to deliver, meaning patients can get back to living their lives rather than spending hours in a hospital chair.
“Managing cancer treatment and regular hospital trips can be really exhausting.
“Not only will this innovation make therapy much quicker and more convenient for patients, it will also help free up vital appointments for NHS teams to treat more people and continue to bring down waiting times”.
Featured Image – NappyStudio (via Unsplash)
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2027 Manchester Marathon sells out in record time after biggest event ever
Danny Jones
The 2027 adidas Manchester Marathon has already sold out in record time after the biggest event in the race’s history.
Incredible stuff.
Yes, after more than 42,000 runners took on this year’s 26.2-mile challenge – the highest number to date – public places for next year’s Manchester Marathon have gone in the blink of an eye.
To be specific, they were snapped up in just 10 days: even faster than the last time around, with 2026 having also broken the previous fastest (or PB, if you will) time before that.
Posting on social media, the organisers wrote: “We’re blown away by the response as a record-breaking number of public places were secured during our launch window, and we’re now officially at capacity.
“Thank you for the amazing support. We can’t wait to help you turn your 26.2 dreams into reality.”
They also went on to remind people that even if they missed out, potential participants can still secure a place through their official charity partners.
Manchester Marathon maintains annual partnerships with the likes of Alzheimer’s Society, British Heart Foundation, Cancer Research UK, Mind, and The Christie Charity.
Teaming up with numerous non-profit organisations over the decades after it first began way back in 1908, before enjoying multiple stints during the 1980s and late 90s into the noughties, huge sums have been raised over the years.
It’s never anything less than a heartwarming and inspiring day.
The modern MCR Marathon, as we know it, returned in its present format nearly a decade and a half ago, beginning its current collaboration with sportswear giants adidas, therefore helping raise the profile even further, with the 2026 fundraising tally also reaching a record-breaking £5.2 million this past April.
At the moment, the Manchester Marathon maintains annual partnerships with the likes of Alzheimer’s Society, British Heart Foundation, Cancer Research UK, Mind, and The Christie Charity.
Once again, these organisations, along with the likes of the Greater Manchester Mayor’s Charity and many more, will continue to offer charity places for the 2027 Manchester Marathon, provided you can hit the fundraising total.
We don’t know about you, but we’re loving this city and the surrounding boroughs being well and truly in their running era, and we also urge all of you who make up part of the local culture to immerse yourself in all aspects – especially when it comes to the post-race season party…
DJs, karaoke, quizzing, three full rooms, an entire beer garden to themselves, and MUCH more. 👀