A clinical trials patient in Manchester is celebrating a new lease of life after having had “a remarkable response” to a new specific gene-targeting treatment that controls how cancer grows.
49-year-old Terri Hurdman, from Bromsgrove in Worcestershire, found out she had advanced bowel cancer on Valentine’s Day two years ago, and didn’t even think she’d make it past Christmas 2021 after finding herself left completely exhausted and out of breath from simple tasks such as climbing the stairs, walking a short distance, or even talking on the phone due to her cancer.
But within hours of trialling a new drug at The Christie NHS Foundation Trust, she was climbing stairs with no effort.
After three months, scans showed her tumours had halved in size.
Terri – who has three children and six grandchildren – was a previously fit and healthy factory worker used to doing manual work for a firm producing medical supplies, and had no symptoms until she got stomach ache and thought it might be IBS – but after having been referred by her GP to Kidderminster hospital, she was diagnosed with stage 4 colorectal cancer, which had spread to her lungs, and started chemotherapy a month later.
After three types of chemotherapy didn’t work, she was told she had no other options and was taken off the drugs.
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By August 2021, Terri had become very ill, had lost a stone and a half in weight, and was becoming weaker, so she was forced to use a wheelchair to get out and about, but luckily, her consultant at Kidderminster hospital knew The Christie in Manchester was running early phase clinical trials which used targeted therapies – a type of cancer treatment that targets the genes and proteins that control how cancer cells grow and spread – and referred her to see if the trial would be suitable.
Terri is taking part in a new experimental drug trial at The Christie in Manchester / Credit: The Christie NHS Foundation Trust
Terri’s DNA had already been analysed as part of standard NHS testing, and it was found she had a mutation in the KRAS gene of her cancer.
Fortunately, the new international clinical trial was designed specifically for people with the gene mutation that Terri has, so she passed the screening and was recruited onto the trial, and immediately after taking the first dose of the tablets last October, her condition “improved significantly”, specialists at The Christie said.
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So much so, Terri was able to walk up some stairs without getting out of breath for the first time in months.
“It’s like a miracle. It really is a wonder drug as within days, I didn’t need to use the wheelchair at all, and I didn’t get out of breath climbing stairs, which would have previously led to a coughing fit,” Terri explained.
“That day, I spoke to my sister on the phone for an hour, something that would have wiped me out before, and my appetite came back, which made me look so much healthier, and the colour returned to my cheeks.
“I didn’t think I’d make it to Christmas, but now I’m looking forward to celebrating my 50th birthday in July.
More Greater Manchester football matches called off as Storm Goretti sets in
Danny Jones
Yet more scheduled football matches in Greater Manchester and the surrounding regions have been postponed and/or cancelled due to Storm Goretti.
The increasingly cold, blustery and icy conditions moving over from France and across more parts of the UK have already caused schools to close, flights to be grounded, and plenty more disruption.
Another such inconvenience has come in the form of live sports, large swathes of which now look like they simply won’t be taking place.
One of the latest to be called off is Salford City‘s upcoming game against Swindon Town in the FA Cup this weekend, with various other games involving teams up and down the footballing pyramid now facing uncertainty over whether their third-round fixtures will go ahead as planned.
Ironically, this is just the tip of the iceberg, if you’ll pardon the very obvious pun.
Another game that was called off late last week, between Chadderton and FC Isle of Man, is yet to be rescheduled; the same is true of Rochdale AFC’s meeting with Brackley Town, Radcliffe v Oxford City, as well as games involving Bury, Stockport Town, Irlam, Cheadle Town, Prestwich Heys and more.
Other nearby outfits, such as Chorley, Warrington Rylands and Ramsbottom United, just to name a few, are also still unsure of when their next game will be.
In many cases, it is simply a matter of the grounds being largely or completely frozen and deemed unfit for use following pitch inspections.
Oldham Athletic – which has already been hit with plenty of snow and frost – yesterday confirmed that their Notts County clash wouldn’t be going ahead due to that very reason.
With winds of up to 90 miles per hour also being reported, yellow and even red weather warnings have been issued across various parts of the country, with people being urged to check their routes home from work by local authorities.
Storm Goretti should start calming down this evening (Fri, 9 January) and into Saturday morning, but the after-effects could still play havoc over the next few days.
For instance, over in Cheshire, Macclesfield FC are going so far as to call on nearby residents to help clear their playing surface from heavy snowfall.
So, if you’re in the area and fancy helping out, they could sure do with your help.
VOLUNTEERS REQUIRED
Macclesfield FC are once again requesting the help of the fanbase and the local community to help clear the remainder of the compacted snow from the surrounding areas of the https://t.co/fL99QEEJ4D Stadium.
Featured Images — Wikimedia Commons/The Manc Group
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Glitzy Spinningfields bar famed for its bottomless deals shuts down
Daisy Jackson
Popular cocktail bar group Banyan has suddenly closed its glitzy bar in the heart of Spinningfields.
The restaurant and bar, which is part of the Arc Inspirations group that also operates Manahatta and Box, has shut down with immediate effect.
A sign has been posted in the window of the Spinningfields site of Banyan confirming its closure.
Banyan opened in 2018 and was the second site for the brand, which has been operating out of the Corn Exchange since 2015.
Inside, the huge 7,000sq ft space was split into spaces for drinking, dining and dancing, including a large mezzanine and a huge white marble bar.
Banyan is famed for its bottomless deals, whether that’s a classic bottomless brunch or their bottomless Sunday roast (endless Yorkshire puddings, gravy, wine, and roast potatoes).
It also offered two-for-one cocktails, all day every day.
The bar stands on the side of Spinningfields, directly opposite The Ivy and alongside The Alchemist.
Banyan in Spinningfields has shut downThe note in the window of Banyan
But now it has permanently closed its doors, thanking people for their custom over its almost-decade in Manchester.
The sign on the door says: “Banyan Spinningfields is now permanently closed.
“Thank you so much for your custom over the years, we’ve loved being part of this wonderful city and have made so many friends.
“Don’t be a stranger, we’d love to continue to welcome you to our Banyan bar in the Corn Exchange. Team Banyan.”