A new study has found that a “game-changing” antibiotic could save millions of lives worldwide from drug-resistant superbugs.
After a team of dedicated UK scientists and researchers were able to use the drug to successfully eradicate methicillin-resistant staphylococcus aureus – a so-called superbug known as MRSA, which is resistant to several widely used antibiotics – in a study on mice, it’s now been hailed as a medical breakthrough.
The breakthrough involved the development of new versions of the molecule teixobactin.
Teixobactin is said to be capable of killing bacteria without damaging the tissue of the mammals it was tested on.
It was first hailed as a “game-changing” antibiotic in 2015, but according to scientists, this new project developed “synthetic” classes of the drug, and because the synthetic versions can be kept at room temperature, global distribution is now much easier.
ADVERTISEMENT
A new study has found that a “game-changing” antibiotic could save millions of lives worldwide from drug-resistant superbugs / Credit: Mark Fletcher-Brown (via Unsplash)
Although global health officials have repeatedly warned about the rise of drug-resistant bacteria and other microbes due to the misuse and overuse of antibiotics – which encourages microorganisms to evolve into “superbugs” – however, future patients could soon be treated with just a single daily dose of teixobactin for systemic life-threatening resistant bacterial infections.
This antibiotic breakthrough comes after the latest figures, according to a January 2021 study in The Lancet, found that in 2019, more than 1.2 million people died from antibiotic-resistant bacterial infections.
ADVERTISEMENT
Additionally, an AMR review commissioned by the UK government has predicted that by 2050, an extra 10 million people will die as a result of drug-resistant infections each year.
Dr Phil Packer, from Innovate UK – the agency which delivered the latest project – said the results had been “excellent”, adding that new classes of antibiotics were especially needed to tackle AMR because existing molecules were already familiar to bacteria, which makes resistance development more likely.
The breakthrough involved the development of new versions of the molecule teixobactin / Credit: Global Panorama (via Flickr)
“We are delighted with results, which have validated synthetic teixobactin’s promise to tackle resistant bacterial infections when currently used antibiotics fail,” he added.
ADVERTISEMENT
“We look forward to following this journey closely in future.”
Speaking on the breakthrough, Health Secretary Sajid Javid added: “It is fantastic to see such innovative work like this happening in the UK – another clear example of this country being at the forefront of scientific advancements which can benefit people across the world.”
Police confirm man was arrested ‘on suspicion of making an explosive device’ in Gay Village
Daisy Jackson
Police have confirmed that the man who was detained in the midst of an incident in the Gay Village yesterday was arrested on suspicion of making an ‘explosive device’.
A huge cordon was in place in the Canal Street area in the city centre on Monday 11 May, after members of the public reported a ‘chemical smell’ coming from a hotel at around 10.45am.
Emergency services attended the scene and found chemical substances in a hotel room.
The man, who was believed to be the occupant of the hotel room, was detained at the scene.
Greater Manchester Police have since confirmed that he was ‘detained on suspicion of making an explosive device’ and was taken into custody for questioning.
In an update shared yesterday, they wrote: “The response to the incident on Canal Street in Manchester city centre is being reduced following reports of chemical substances being found.
“Emergency services examined items within a room inside a hotel following calls from the public at about 10:45am.
“A man, believed to be the occupant of the room, was detained on suspicion of making an explosive device and is currently in custody being questioned.
“Chemical substances found in the room have been examined and are in the process of being safely removed. The subsequent examination ruled out any explosive risk.
“We are working with the hotel management to return the establishment to normal after staff and guests were evacuated as a precaution.
“Staff from the fire service’s Hazardous Materials and Environmental Protection team remain in attendance to conduct tests and ensure the area is safe.
“We would like to thank the public and surrounding businesses for their patience as we continue with our work.”
No trams to run on major Greater Manchester line for two weeks as part of £150m improvement works
Emily Sergeant
Major disruption is on the horizon, as no trams are set to run on a major Greater Manchester line for two weeks this month.
As the next phase of the ongoing £150m investment into Greater Manchester’s tram network gets under way this month, essential track replacement work is set to be be carried out in a bid to make the network ‘safer’ and ‘more resilient and reliable’ for years to come.
Due to improvement works on the Oldham-Rochdale line – which is being carried out between Monsall and Newton Heath & Moston – there will be no trams between Manchester Victoria and Rochdale town centre for two weeks, starting from this Saturday 16 May right through to Friday 29 May.
The work being carried out will involve replacing sections of track and improving drainage along the route.
The track foundation will also be replaced where needed, as well as work to correct the alignment and level of the track.
No trams will be running on a major Greater Manchester line for two weeks from this weekend / Credit: TfGM
Transport for Greater Manchester (TfGM) has conceded that this is a ‘big and complex job’ – with 290 new concrete sleepers and 2,000 tonnes of pea gravel being used, and more than 5,000 tonnes of ballast set to be replaced.
But, when the work is done, it’s aiming to make journeys ‘smoother and more reliable’ for passengers, while improving the condition of the track for the long-term.
While the work is being carried out and the line is closed, bus replacement services will be in place between Victoria and Rochdale Town Centre, and more frequent Bee Network bus services will also call at the bus stops near each tram stop too, however tram tickets will only be accepted on the replacement bus, not on numbered bus services.
Elsewhere, work at Derker will also take place at the same to ‘minimise disruption’.
The track was made safe following a landslip in summer 2024, but now, a longer-term solution will see teams drive steel sheets into the ground to hold it in place and prevent further movement, before further work will be needed later in the year to complete the job.
And to top it off, from Monday 25 to Friday 29 May, improvement work to update equipment that has been in place since the line opened in 1992 will also take place at Piccadilly Gardens, and that means no trams will run between St Peter’s Square/Market Street and Piccadilly during this time.
Customers may need to change trams, take a short walk, or hop on the free bus to continue their journey.
Tram services will resume as normal from the start of service on Saturday 30 May, and passengers travelling during this period are urged to ‘plan ahead’.
Everything you need to know about the planned works is on the TfGM website here.
Emily Sergeant -
29th March 2022 
