NHS England has secured a new deal which means that children with peanut allergies in the UK will be the first to receive a groundbreaking new treatment.
The oral treatment – named Palforzia – decreases the severity of symptoms brought on by peanut allergies, including the potentially life-threatening allergic reaction known as anaphylaxis, and will soon be available to up to 600 children aged four to 17 the first year, and 2,000 the following year, thanks to the new deal.
The deal has been secured after Evelina London Children’s Hospital took part in two large peanut allergy trials – the Palisade and Artemis studies.
Both trials are said to have transformed the lives of some of its participants.
“This pioneering treatment can be life-changing for patients and their families and, thanks to the deal the NHS has struck, people here will be the first in Europe to benefit,” explained NHS Medical Director, Professor Stephen Powis.
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“It will reduce the fear and anxiety for patients and their families who may have been living with this allergy for years.
“And carrying around emergency medication just in case.
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“They should be able to enjoy meals out or holidays abroad together without worrying about an allergic reaction that could land them in hospital or worse.”
Palforzia decreases the severity of symptoms brought on by peanut allergies, including anaphylaxis / Credit: Flickr
In the UK, peanut allergies are currently said to affect one in 50 children.
The Artemis study, in particular, found that around six in 10 of the participants aged four to 17, who reacted to around 10mg of peanut protein at the start of the trial, were able to take a dose of 1,000mg by the end, which is well above the amount of accidental exposure.
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As mentionted, around 600 children aged four to 17 are expected to be treated with Palforzia this year, and the after that, some 2,000 children will be treated a year.
Professor George du Toit – Children’s Allergy Consultant at Evelina London – was senior investigator for the UK for both of the trials, and has called the rollout of the treatment “great news” for children and young people with peanut allergies.
“This will make a huge impact to the everyday lives of our patients and their families,” he added.
Travel warning issued as Manchester braces for busiest day of the year so far
Daisy Jackson
A ‘plan ahead’ travel warning has been issued for this weekend as the Manchester Marathon brings the busiest day of the year so far on the tram network.
Tens of thousands of people will hit the streets to take part in the race itself, with thousands more cheering them on from the sidelines.
This year’s Manchester Marathon route takes 36,000 runners through Sale, Stretford and Timperley before finishing up at a new finish line on Oxford Road – and there’ll be some big changes to your usual travel routes to accommodate this.
TfGM has said that Bee Network trams will be very busy before, during and after the 26.2 mile race, especially in Manchester and Trafford, with a number of road closures in place too.
Taking place on Sunday 27 April, the Manchester Marathon will coincide with Manchester’s popular St George’s Day parade which starts and ends across town around Oldham Road and Great Ancoats Street.
People are being encouraged to plan their journeys carefully this weekend, as it’s expected to be the busiest day of the year on the Bee Network trams.
The Manchester Marathon last year set a new personal best for the tram network, with 175,000 tram journeys racked up – the highest ever recorded on a single Sunday.
Trams will be the best choice to get around the Manchester Marathon course with key stops along the route including Sale, Timperley and Chorlton.
Many road closures will also be in place but at different times of day, so make sure you check HERE for the latest.
This will impact bus services, which will be on diversion from 8am until the end of service on Sunday, with traffic and congestion expected on surrounding roads.
Runners heading to the start line will only be able to access the athletes’ village from Old Trafford and Trafford Bar tram stops up until 9am. Participants arriving after 9am should get off at Wharfside or Exchange Quay instead.
Metrolink is promising to deploy as many double trams as possible across the network, with additional services between Piccadilly and Timperley.
As for other modes of transport, those who wish to drive should make us of Park and Ride facilities where possible; and those on the train should note that Salford Central remains closed with bus replacements in place.
Danny Vaughan, Chief Network Director at TfGM said: “The Manchester Marathon is a highlight of the Manchester city centre calendar and our job is to make sure everyone can get to and from the event as smoothly as possible.
“We want everyone to have a great day – whether they are taking on the run themselves or cheering on a friend or loved one – and would urge people to plan their journey in advance, leave plenty of time and check the Bee Network app or website for the most up-to-date information.
“The start and finish lines will be especially busy so if you are coming to watch you may be better off catching the tram to Sale, Timperley or Chorlton, grabbing a coffee and claiming afront row seat to cheer runners on.
“Using public transport is the best way to avoid congestion and delays – and with Tap and Go contactless payments it’s never been easier or more seamless to get around Greater Manchester by bus and tram.”
Passengers can now travel seamlessly between bus and tram and pay for their journey by tapping on when boarding a bus without the need for a ticket, making it the quickest and easiest way to pay for travel.
People travelling on Bee Network buses on Marathon Day can simply tap in and pay £5 for the day on as many buses as they need and just £4.90 on the tram. You can use all Bee Network buses as much as you want all day from just £5.40*.
Kirsty Wilde, Operations Director, from Manchester Marathon organisers A.S.O. UK, said: “The TfGM tram service is an invaluable part of our event, which allows thousands of participants and supporters to navigate around the city. With a record-breaking 36,000 participants set to take part on Sunday 27th April – and more exciting activities taking place over the weekend as a whole – we’re anticipating a rise in tram journeys, which will subsequently bring economic benefits to local vendors, the hospitality sector, and retail businesses.
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“We’d like to thank Transport for Greater Manchester for its continued hard work helping to facilitate what will be the largest event yet, and would also like to say a big thank you to the residents and businesses across Greater Manchester for their understanding and support.”
The viral factory in Oldham that sells £2 Colin the Caterpillar cakes
Thomas Melia
A factory in Oldham has gone viral online after sweet fiends discover they sell ‘Colin the Caterpillar’ cakes for less than half price.
There are some things that just go hand in hand: a brew and a biscuit, peanut butter and jelly and Brits and their crazy obsession with a character chocolate cake from M&S called Colin the Caterpillar.
Since hitting the shelves in 1990, more than 15 million Colin the Caterpillars have made their way from supermarket shop floor to our sweet-treat-awaiting plates.
Who would’ve ever guessed that the home to this cheeky chappy, who M&S have made their unofficial mascot (after Percy Pig, of course), has been crafted and created right here in Oldham?
The utterly delicious Colin the Caterpillar cake which you can get for £2 at Park Cakes.The shelves at Park Cakes are stacked with Colins and Connies.Credit: The Manc Eats
Established in 1937, The Park Cake Bakeries – or just Park Cakes, colloquially – has been serving up this critter-inspired cake for over 30 years, and savvy shoppers have flocked to their factory shop to get their hands on some very sweet savings.
There’s a whole range of cakes on offer at this Oldham dessert factory shop, including slabs, sponges, loaves and even sweet pies too.
Whether you’re a firm believer that the birthday person deserves all of Colin’s white-choc face or you precisely cut it up so everyone gets some, Park Cakes has the solution, selling bags of the character’s chocolatey face so you can have one all to yourself.
The cake isn’t the only thing that leaves a sweet taste in your mouth, as the prices will too. Colin the Caterpillar, who normally retails for just under a tenner, is sold for around £2 at this Oldham factory shop.
It’s always the ones that look unassuming, isn’t it?
Alongside producing one of the most adored cakes in the UK, they’re also responsible for lots more of your favourite supermarket sweet treats, and we’re definitely not complaining.
You can let your sweet tooth go wild in this factory shop as they sell everything from rainbow birthday cakes to sticky toffee puddings.
There’s so much on offer too, how about a giant bag packed to the brim with misshapen golden flapjacks that’ll last you over a week and cost you less than a fiver? Sounds like a plan to me.
If you haven’t had enough of your Easter chocolate fix, why not trek over to Oldham and stock up on even more chocolate and sweet treats? Trust us, there’s plenty to choose from.
Park Cakes factory shop can be found on Ashton Road in Oldham and is open from 10am-4pm, so go and grab yourself a seriously sweet deal before everyone else beats you to it.
Mini Colins, small in size but still packed with all that chocolatey goodness.Flapjacks and cookie dough bites are just some of the wonderful treats you might be able to get hold of.Credit: The Manc