It’s been announced today that the Medicines and Healthcare products Regulatory Agency (MHRA) has approved a new COVID-19 treatment for use in the UK.
Following a rigorous review of its safety, quality, and effectiveness by the UK regulator and the government’s independent expert scientific advisory body, the Commission on Human Medicines, the treatment was found to successfully reduce the risk of hospitalisation and death in people with mild to moderate COVID-19 infection, who are at an increased risk of developing severe disease.
The treatment – known as Xevudy (sotrovimab) – has been developed by GSK and Vir Biotechnology, and is a single monoclonal antibody that, according to a statement published by the UK government website, works by binding to the spike protein on the outside of the COVID-19 virus.
This in turn prevents the virus from attaching to and entering human cells, so that it cannot replicate in the body.
Xevudy is the second monoclonal antibody therapeutic to be approved, following Ronapreve.
In a clinical trial, a single dose of the monoclonal antibody was found to reduce the risk of hospitalisation and death by 79% in high-risk adults with symptomatic COVID-19 infection, and based on the clinical trial data, the government says sotrovimab is most effective when taken during the early stages of infection.
And so, the MHRA has said it recommends its use as soon as possible and within five days of symptom onset.
BREAKING NEWS:
A new treatment against COVID-19 has been approved by @MHRAgovuk.
We'll closely monitor how effective Xevudy is against the Omicron variant and will work on deployment plans with the NHS.https://t.co/ZilAKtwdaO
The approval for use of this treatment follows the confirmation that the first pill to treat symptomatic COVID-19 – molnupiravir – has also been approved for use in the UK back at the start of November.
Like molnupiravir, Xevudy has been authorised for use in people who have mild to moderate COVID-19 infection, and at least one risk factor for developing severe illness – such as obesity, older age (+60 years), diabetes mellitus, or heart disease – but unlike molnupiravir, sotrovimab is administered by intravenous infusion over 30 minutes, and it has also been approved for individuals aged 12 and above who weigh more than 40kg.
The MHRA says it’s too early to know whether the Omicron variant has any impact on sotrovimab’s effectiveness, but the body will work with the company to establish this.
The Medicines and Healthcare products Regulatory Agency (MHRA) has approved a new COVID-19 treatment for use in the UK / Credit: Pixabay
“I am pleased to say that we now have another safe and effective COVID-19 treatment, Xevudy (sotrovimab), for those at risk of developing severe illness,” announced Dr June Raine, Chief Executive of the MHRA.
“This is yet another therapeutic that has been shown to be effective at protecting those most vulnerable to COVID-19, and signals another significant step forward in our fight against this devastating disease.
“With no compromises on quality, safety and effectiveness, the public can trust that the MHRA have conducted a robust and thorough assessment of all the available data.”
Featured Image – Flickr
News
The Warehouse Project 2025 – full calendar, lineups, tickets, stage times and more
Thomas Melia
The summer and festival season may be almost over, but the Manchester music calendar is still going strong with The Warehouse Project announcing its full 2025 lineup.
If there’s one thing Manchester has got you covered for, it’s live music, and this EDM favourite returns year in and year out to power you through the winter – trading your dark nights for DJ sets with vibrant strobes and lasers.
The Warehouse Project know how to deliver a series of absolutely incredible b2b sets, exclusive shows and more, with the 2025 calendar looking just as impressive as previous years.
This latest full calendar lineup covers you with some of the best music events from 12 September right through til 31 December – grab your mates and your diaries, it’s time to get your next rave booked in.
Everything you need to know about The Warehouse Project 2025
The Warehouse Project tickets
As mentioned, with events running until 31 December, there are plenty of tickets available; however, with growing popularity annually and some of the biggest acts performing, these will be in high demand.
You can find the full calendar online, highlighting what events are still on sale – yes, the majority sell out fast every year – and takes you directly to their website HERE.
WHP stages
There are three separate rooms, which range in capacity, sound and facilities:
Depot is the largest room, boasting a capacity of 10,000.
Concourse can accommodate a significant 2,500 concertgoers.
Archive still holds an impressive 1,900.
It’s also worth noting that the Concourse room will now operate a strict no phones rule this year. The venue has been flagging a number of ‘Concourse only’ shows over the last few weeks in an effort to soft-launch the new policy.
Limited to the mid-sized room only for now, they’re taking cues from the likes of popular Manc nightclub Amber’s, insisting that they “feel that club culture is best enjoyed in the moment with your friends, and your phone in your pocket.”
Amber’s is also relaunching their newly formatted ‘Room Two’.
For anyone at all frustrated about this news, at least take the news of new ‘proper flushable toilets’ being installed through 80% of the venue this year as a pretty decent silver lining.
Transport and how to get to The Warehouse Project
This iconic EDM music series moved from its Victoria Warehouse to another music hotspot, Depot Mayfield, back in 2019 and has seen some of the greatest artists and DJs grace these very four walls.
Just an eight-minute walk from Manchester Piccadilly or a 20-minute walk from Manchester Victoria Station, it’s super easy to get to on foot or via public transport.
You can catch a train or multiple tram lines from Victoria and various other points around the city centre, which will drop you off at Manchester Piccadilly; better still, a tram journey will only set you back £1.90 and not much more for the train.
Friday, 12 September – DJ HEARTSTRING
Electronic duo DJ HEARTSTRING are swapping the cold city centre feels of Berlin for the equally chilly Manchester to kick off the WHP25 series.
Playing in the Concourse, they will also be joined by a handful of acts, including Peach, Niamh and Ireland-born but now Berlin-based act, Spray.
Saturday, 13 September – D.O.D
Dan O’ Donnell, more widely recognised by his stage name and acronym D.O.D, is playing a huge hometown show in the Concourse with more DJs and mixers yet to be announced.
The Bury-born talent has a roster of hits and remixes under his belt, including ‘So Much In Love’, ‘Azizam (D.O.D Remix)’ and ‘Somedays’, the latter a collaboration with previous Warehouse Project alumni Jazzy.
Friday, 19 September – ANOTR
You might get ‘Vertigo’ from this next duo, who are currently soaking up the Ibiza club scene before making their way to the prestigious Manchester event later this year.
Amsterdam-based duo ANOTR are gearing up to play in the Concourse with a selection of yet-to-be-announced acts, and we’re sure you’ll want to ‘Turn It Up’ when they visit.
It’s time to get ‘Jamming’ with gold-coast music producer Fisher and we’re sure you’ll be ‘Losing It’ as soon as you feel the ‘Atmosphere’ at Depot Mayfield on this night.
Ranked as one of the top 10 DJs in DJ Mag’s top 100 DJs of 2024 and surpassing over 18 million monthly listeners on Spotify, expect this to be a busy one.
Friday, 26 September – Worried About Henry
All three rooms are in use for this event, and if you were at Parklife this year, you know this drum and bass event organiser knows how to start a party.
There are over 30 acts playing out across the night, and although we can’t list them all, expect Andy C, Wilkinson, Sub Focus in Depot, Camo and Krooked b2b K Motionz in Concourse and Simula in Archive.
Saturday, 27 September – YOU&ME 10th Birthday
Can you feel the buzz? We certainly can, as legendary DJs Josh Baker and Max Dean are in residency for a landmark Warehouse Project birthday celebration.
This London name has been behind some of house and UK garage’s recent anthems like ‘If U Need It’ and ‘Cops & Robbers’ with his 2020 album ‘Spice Up My Life’ reaching No.7 on the Official Dance Charts.
Now, the record producer is teaming up with a specially selected DJ crew at Depot Mayfield, including Armand Van Helden, Bakey, Joy Orbison and local lad Ghoulish.
Saturday, 4 October – &ME
Techno giant has worked on numerous collaborations and solidified his place in the house music scene with remixes and originals like ‘Say What’, ‘Thandaza’ and ‘More Love – Rampa &ME Remix’.
Coming to the Concourse, he’ll be joined by two other notable music creators like ‘P*ssy Power’ hitmaker Desiree and ‘Intuition’ credited act Megatronic.
Friday, 10 October – Dom Dolla
We’ve been ‘Dreamin’ about this one for a while, and after his latest tune gaining a spot on the F1 The Movie soundtrack, ‘No Room For A Saint’, this dance act has definitely earned its stripes.
The Australian producer is set to play Depot Mayfield, which will mark his only UK headline show outside London in 2025, and he’s bringing a couple of house music acts along for the ride too.
Saturday 11 October – Defected & Glitterbox
Depot Mayfield and Concourse are getting new names for one night only, with the larger of the two becoming ‘Defected’ and the latter taking on its new title of ‘Glitterbox’ while Archive keeps its moniker.
The legend himself, MK, will be in attendance and after the success of his recent hit ‘Dior’ with Bolton act Chrystal, the Manchester crowd will be lapping him up.
Friday, 17 October – Jamie Jones presents Paradise
Well-established Welsh DJ Jamie Jones is fronting the bill on this event, with the rest of the lineup awaiting announcement.
One thing is for sure, if the talent on the night takes any homage or inspiration from Jones’ records like ‘Lose My Mind’ and ‘We Groovin’, this will be a night of dancefloor fillers across Depot Mayfield.
17.10 /// JAMIE JONES PRESENTS PARADISE – LINE UP REVEALED
Jamie Jones brings Paradise back to WHP this October. Jamie plays a special b2b with Joseph Capriati plus across the evening he will be joined by East End Dubs, Alisha, Ahmed Spins, Obskür and more.
‘Is U’ looking to get ‘Lippy’? Well, Overmono have just the set for you when they present their new show to you alongside a curated lineup of special guests at Depot Mayfield.
Fellow collaborator Joy Orbison will be popping up with chart-topping act Interplanetary Criminal in Concourse and a selection of artists in Archive, hosted by Virus.
Friday, 24 October – Confidence Man
Janet Planet and Sugar Bones are ready to take you on a ‘Holiday’ when they return to Manchester with their celebrated records and unmissable dance moves.
Also bringing the heat to Manchester on this night is Antony Szmierek, who’s trading ‘The Great Pyramid of Stockport‘ for Depot Mayfield with Archive hosted by city centre nightlife venue and bar, Yes.
Saturday, 25 October – Black Coffee
After working with notable artists like Drake, David Guetta and Alicia Keys, this caffeinated music creator is ready to power you through the night with a selection of hits from his stacked roster.
Although the support is to-be-announced, this lineup will be one you definitely don’t want to miss out on.
Wednesday, 29 October – Aitch
Moston rapper Aitch is touching down on home turf to play his huge hits out to Depot Mayfield with the release of his latest album 4 earlier this summer.
Collaborating with drum and bass heavyweight Bou on ‘Raving in the Studio’ has been great exposure too, with the Manc star receiving a warm welcome from dance music lovers.
Friday, 31 October – WHP25 Halloween – Warehouse Banger
Another one of The Warehouse Project’s biggest nights of the year, there will be lots of dance, house, drum and bass artists decorating the bill.
With no official lineup yet, expect this night to be spook-tacular.
Saturday, 1 November – Marlon Hoffstadt presents Party of the Year
‘It’s That Time’ and by that time we mean Marlon Hoffstadt’s self-proclaimed ‘Party of the Year’, which is bringing good vibes only to Depot Mayfield.
Artists include Biianco, Surf 2 Glory and Horsegiirl, who sat hoof-to-hoof with TV Royalty Danny Dyer at this year’s Brit Awards.
Friday, 7 November – Rossi.
‘Don’t Touch That Dial’ because the ‘Freak in the Sheets’ is heading to Manchester for a night dedicated to all things Rossi.
He has been on a roll this year appearing at various music festivals from Parklife to Glastonbury, and has even headlined this dance music event before in 2023. It’s safe to say that much like his track – ‘Little Man’, we’re ‘(Proud of You)’.
Friday, 21 November – Barry Can’t Swim – Earth’s Only Paradise
Probably one of our favourite electronic acts around right now, full stop.
All three rooms are open for Barry Can’t Swim, who ( in our not-so-biased opinion) might have one of the best DJ names of all time.
He’ll be bringing along a whole gathering of notable DJ figures like Jayda G, Chloé Caillet, and Prospa as he hosts his ‘Earth’s Only Paradise’ event.
Saturday 22 November – The Hacienda
Manchester has always been a city of clubgoers, and it’s lovely to see the musical history of the music capital of the North celebrated via a dedicated night to its most legendary club, The Hacienda.
Expect Depot Mayfield to be filled with all the greats from DJ Paulette, Groove Armada, Primal Scream and more.
Aussies are well and truly feeling the love from the Manc crowd this year, with a variety of acts making the over 20-hour flight to play their club classics, and now Sonny Fodera joins this list.
Fodera has worked with Calvin Harris, Jazzy, Becky Hill, Glass Animals, and Sinéad Harnett, just to name a few – so expect to hear a lot of recognisable tunes throughout the night.
Wednesday 31 December – New Year’s Eve
The lineup for this one is always a secretive one, but as you’re welcoming in the New Year, what better way to do it than attending a night soundtracked by dance and house anthems.
The Warehouse Project New Year’s Eve event is usually a big one, so expect tickets to this exclusive party to sell out pretty quickly.
Body found in search for missing man Craig Foy after police scour Heaton Park
Daisy Jackson
A body has been discovered in the search for missing Bury man Craig Foy.
Greater Manchester Police’s Major Incident Team had been carrying out an extensive search for Craig, 40, after he disappeared on Saturday 26 July.
Those searches had included the Heaton Park area, after CCTV appeared to show the Whitefield man climbing into the park just before midnight.
Officers have now confirmed that a body has been found in connection with the investigation.
While formal identification is yet to take place, it’s believed to be that of Craig.
Craig’s family have been informed and are being supported by specialist officers.
Earlier in the week, GMP said that three men were arrested on suspicion of murder, with one suspect since released on bail and two others facing no further action.
Detective Chief Inspector Jill Billington, from GMP’s Serious Crime Division, said: “The investigation remains ongoing to establish the circumstances leading up to Craig’s death, and to ensure that we can get the answers that his family deserve.
“We appreciate the support of the public in sharing our appeals to locate Craig and ask for his family to be given privacy, space and time to process their loss.”
Police are still appealing for information relating to the investigation – you can contact GMP on 101 quoting log number 917-28/7/25 or via Crimestoppers on 0800 555 111.
The Manc -
2nd December 2021 
