It’s been announced today that the Medicines and Healthcare products Regulatory Agency (MHRA) has approved a new COVID-19 treatment for use in the UK.
Following a rigorous review of its safety, quality, and effectiveness by the UK regulator and the government’s independent expert scientific advisory body, the Commission on Human Medicines, the treatment was found to successfully reduce the risk of hospitalisation and death in people with mild to moderate COVID-19 infection, who are at an increased risk of developing severe disease.
The treatment – known as Xevudy (sotrovimab) – has been developed by GSK and Vir Biotechnology, and is a single monoclonal antibody that, according to a statement published by the UK government website, works by binding to the spike protein on the outside of the COVID-19 virus.
This in turn prevents the virus from attaching to and entering human cells, so that it cannot replicate in the body.
Xevudy is the second monoclonal antibody therapeutic to be approved, following Ronapreve.
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In a clinical trial, a single dose of the monoclonal antibody was found to reduce the risk of hospitalisation and death by 79% in high-risk adults with symptomatic COVID-19 infection, and based on the clinical trial data, the government says sotrovimab is most effective when taken during the early stages of infection.
And so, the MHRA has said it recommends its use as soon as possible and within five days of symptom onset.
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BREAKING NEWS:
A new treatment against COVID-19 has been approved by @MHRAgovuk.
We'll closely monitor how effective Xevudy is against the Omicron variant and will work on deployment plans with the NHS.https://t.co/ZilAKtwdaO
The approval for use of this treatment follows the confirmation that the first pill to treat symptomatic COVID-19 – molnupiravir – has also been approved for use in the UK back at the start of November.
Like molnupiravir, Xevudy has been authorised for use in people who have mild to moderate COVID-19 infection, and at least one risk factor for developing severe illness – such as obesity, older age (+60 years), diabetes mellitus, or heart disease – but unlike molnupiravir, sotrovimab is administered by intravenous infusion over 30 minutes, and it has also been approved for individuals aged 12 and above who weigh more than 40kg.
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The MHRA says it’s too early to know whether the Omicron variant has any impact on sotrovimab’s effectiveness, but the body will work with the company to establish this.
The Medicines and Healthcare products Regulatory Agency (MHRA) has approved a new COVID-19 treatment for use in the UK / Credit: Pixabay
“I am pleased to say that we now have another safe and effective COVID-19 treatment, Xevudy (sotrovimab), for those at risk of developing severe illness,” announced Dr June Raine, Chief Executive of the MHRA.
“This is yet another therapeutic that has been shown to be effective at protecting those most vulnerable to COVID-19, and signals another significant step forward in our fight against this devastating disease.
“With no compromises on quality, safety and effectiveness, the public can trust that the MHRA have conducted a robust and thorough assessment of all the available data.”
Featured Image – Flickr
News
A literacy charity is making its way to Manchester bringing lots of FREE books
Thomas Melia
A charity dedicated to literacy is coming to Manchester in May providing families and individuals with plenty of free books.
Led by Bookbanks, this London-founded organisation was set up in line with food banks to provide people with access to free books and now they’re coming all the way to Manchester.
This charity started in 2022 all thanks to writer and journalist Emily Rhodes, who has read her fair share of books and wants to give this privilege to anyone who might not be able to get their hands on any.
The charity has seen widespread positive reception quickly expanding into Norfolk and is now partnering with various food banks in Manchester, marking the organisation’s first Northern venture.
Bookbanks gives out an average of 30 books per week, per site and has distributed over 5,000 books so far at food banks.
Crates being organised in Manchester food bank.Credit: Publicity Picture (via Supplied)
Titled Bookbanks after the fact that they work very closely with food banks to provide books far and wide to food banks across the UK, they also host a range of interactive events.
Alongside all the fantastic work the team do, there’s a handful of free workshops and author events on offer for all ages and backgrounds, to further build the connection between people and their books.
Currently, there are two famous figures backing this book-based charity, Elizabeth Day and Andrew O’Hagan, both of which are no stranger to a pen and paper.
Day is an award-winning author who has written nine fiction and non-fiction books to date, while O’Hagan is Booker Prize nominated and is London Review of Books’ Editor-at-Large.
Bookbanks relies on the general public to spread their message further and there’s even a section on their website detailing how you can get involved to continue distributing books within food banks.
One of Bookbank’s many free author events, some of which will hopefully take place in Manchester.Credit: Publicity Picture (via Supplied)
Whether you’re an avid runner or keen to try something new why not raise money for and be sponsored by Bookbanks, knowing you’ve done your bit to bring books to those who need them most.
If you don’t fancy lacing up those trainers and heading out for a run, why not donate any old books you’ve finished reading to this book-focused charity and allow others to discover a whole new world of reading.
Bookbanks first official Manchester site will launch on Friday 2 May at Manchester Central Food bank and a second site is already in talks at Greater Together Manchester’s Social Supermarket in Miles Platting.
To find out more ways to get involved as a company, publisher, member of public and more, you can find all information on their official site HERE.
Featured Image: Publicity Picture via Annabelle Williams
News
Touching tribute paid to man and his dog who died together in fatal collision
Daisy Jackson
The family of a man who was killed in a fatal collision last month, alongside his beloved dog, have paid tribute to him.
Andrew Old, 61, had been walking along Greenwood Road in Wythenshawe when he was struck by a vehicle that had been involved in a collision.
He had been waking his ‘lovely’ dog, Liddy, who also died at the scene.
Emergency services rushed to the scene on Sunday 9 March but tragically both Andrew and his beloved pet passed away.
Paying tribute to him, Andrew’s family said: “Andrew was our happy go lucky brother and he is so sadly missed by us all.
“We miss his smiles, his laughter, his jokes and his hourly phone calls.
“Words cannot describe the shock and disbelief that we feel due to the loss of Andrew, we are absolutely devastated.
“Andrew tragically died only metres from his home, whilst walking his lovely dog Liddy.
“The only solace we have is that Andrew and Liddy were not alone at such a horrific time and that they were together. Andrew and Liddy will always be in our hearts.”
The Manc -
2nd December 2021 
