It’s been announced today that the Medicines and Healthcare products Regulatory Agency (MHRA) has approved a new COVID-19 treatment for use in the UK.
Following a rigorous review of its safety, quality, and effectiveness by the UK regulator and the government’s independent expert scientific advisory body, the Commission on Human Medicines, the treatment was found to successfully reduce the risk of hospitalisation and death in people with mild to moderate COVID-19 infection, who are at an increased risk of developing severe disease.
The treatment – known as Xevudy (sotrovimab) – has been developed by GSK and Vir Biotechnology, and is a single monoclonal antibody that, according to a statement published by the UK government website, works by binding to the spike protein on the outside of the COVID-19 virus.
This in turn prevents the virus from attaching to and entering human cells, so that it cannot replicate in the body.
Xevudy is the second monoclonal antibody therapeutic to be approved, following Ronapreve.
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In a clinical trial, a single dose of the monoclonal antibody was found to reduce the risk of hospitalisation and death by 79% in high-risk adults with symptomatic COVID-19 infection, and based on the clinical trial data, the government says sotrovimab is most effective when taken during the early stages of infection.
And so, the MHRA has said it recommends its use as soon as possible and within five days of symptom onset.
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BREAKING NEWS:
A new treatment against COVID-19 has been approved by @MHRAgovuk.
We'll closely monitor how effective Xevudy is against the Omicron variant and will work on deployment plans with the NHS.https://t.co/ZilAKtwdaO
The approval for use of this treatment follows the confirmation that the first pill to treat symptomatic COVID-19 – molnupiravir – has also been approved for use in the UK back at the start of November.
Like molnupiravir, Xevudy has been authorised for use in people who have mild to moderate COVID-19 infection, and at least one risk factor for developing severe illness – such as obesity, older age (+60 years), diabetes mellitus, or heart disease – but unlike molnupiravir, sotrovimab is administered by intravenous infusion over 30 minutes, and it has also been approved for individuals aged 12 and above who weigh more than 40kg.
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The MHRA says it’s too early to know whether the Omicron variant has any impact on sotrovimab’s effectiveness, but the body will work with the company to establish this.
The Medicines and Healthcare products Regulatory Agency (MHRA) has approved a new COVID-19 treatment for use in the UK / Credit: Pixabay
“I am pleased to say that we now have another safe and effective COVID-19 treatment, Xevudy (sotrovimab), for those at risk of developing severe illness,” announced Dr June Raine, Chief Executive of the MHRA.
“This is yet another therapeutic that has been shown to be effective at protecting those most vulnerable to COVID-19, and signals another significant step forward in our fight against this devastating disease.
“With no compromises on quality, safety and effectiveness, the public can trust that the MHRA have conducted a robust and thorough assessment of all the available data.”
Featured Image – Flickr
News
Gary Lineker set to leave BBC this week following more controversy
Danny Jones
Former footballer and veteran presenter Gary Lineker is set to leave the BBC earlier than expected following further political controversies and social media backlash.
Lineker has been butting heads with the presenter for a couple of years now, being suspended by the national corporation back in March 2023 for his comments about language used by the Conservative government, and has continued to take issue with certain aspects of their news coverage.
He has since gone on to share a further video expressing his regret over what he called an “honest mistake”, as well as confirming that he will be making a premature exit from the BBC.
As you can see in the clip above, he says: “I apologise unreservedly for the hurt and upset caused,” insisting that he didn’t see the emoji in question
Lineker is now expected to leave following his final Match of the Day programme this weekend after having already confirmed he would be leaving the role after 26 years at the end of the season.
The ex-English footballer was set to present the 2026 FIFA World Cup next summer, but given the latest furore, he will be stepping away ahead of schedule.
Having gradually wound down his work with networks like TNT Sports (previously BT Sport) and the BBC in recent years, he has been slowly shifting his focus to his own Goalhanger Podcasts company, which includes several popular audio formats under The Rest Is… brand, including his own flagship The Rest Is Football show.
He goes on to add that he’s “stood up for minorities and humanitarian issues and against all forms of racism all my life.” Since the most recent Israel-Palestine conflicts began, he’s been particularly outspoken on the events. One recent interview with the BBC itself sparked plenty of discussion online.
Gary Lineker, "What's going on there (Gaza), the mass murder of thousands of children is something we should have an opinion on"
Amol Rajan, "The BBC needs to be impartial about it"
Lineker reiterated that he would never “knowingly share anything antisemitic” and removed the problematic post as soon as he was made aware.
Nevertheless, the BBC and director general Tim Davie have been facing pressure to address the situation ever since it happened, with many calling for the household name to be sacked.
It seems the ex-Everton, Leicester, Spurs and Barcelona player has made the decision for them.
As he goes on to conclude, despite expressing gratitude regarding his relationship with the BBC, he feels the “time is right […’ to go our separate ways.”
“Wildfires can spread quickly and cause devastation to the land and wildlife on it,” explained GMFRS’s wildfire lead and national tactical adviser for wildfires, Ady Taylor, “so it’s vitally important that people call 999 as soon as they think they see a fire.”
He continued: “We want people to enjoy the countryside and moorland we have in Greater Manchester, but… [we] remind people to always act responsibly while out enjoying these environments.
“This means no BBQs, fires or fireworks – as they can easily result in wildfires.”
On Wednesday 14 May 2025, a teenage boy was arrested on suspicion of arson and interviewed by police in relation to the incident, and then the following day on Thursday 15 May 2025, another two boys were also arrested – with each of the three having now been released on bail pending further enquiries while investigations are ongoing.
Three teenagers have been arrested on suspicion of arson after a large moorland fire in Bury / Credit: Wikimedia Commons
Detective Inspector Andy Wright, from GMP’s Bury district, added: “The moorland fire is being investigated as arson following information from a witness and enquiries we have made.
“We have managed to apprehend three teenagers in relation to this incident, all of them have been bailed following interviews with our officers.”
GMP and GMFRS is reminding Greater Manchester residents that if they see a fire in the countryside, they need to report it immediately, leave the area as soon as possible, and dial 999, and if you witness illegal activity in relation to the fire, then you can report it to Crimestoppers on 0800 555 111
“Fires can have such a devastating effect, and we are lucky that this has not caused a significant amount of damage, or cost lives,” Detective Inspector Andy Wright concluded.
The Manc -
2nd December 2021 
