Parkinson’s Disease could be diagnosed with skin swab tests, Manchester scientists discover
Scientists at the University of Manchester have made a “game-changing” breakthrough by discovering that Parkinson’s Disease could be diagnosed using a simple skin swab test.
Scientists at the University of Manchester have made a “game-changing” breakthrough by discovering that Parkinson’s Disease could be diagnosed using a simple skin swab test.
Results published this week showed that Parkinson’s sufferers may produce higher amounts of a substance called sebum – which coats and protects the skin.
A swab test can detect these compounds; and may help researchers determine whether new treatments are able to slow, stop or reverse the progression of the disease.
The study was funded following the case of Joy Milne – a woman who stunned scientists by revealing she could detect Parkinson’s disease through smell.
Joy told researchers that she could smell a “musky” odour on her husband Les – who was diagnosed with Parkinson’s years later.
Professor Perdita Barran, Professor of Mass Spectrometry at UoM, said the results were “an extremely encouraging step” towards tests that could be used to help diagnose and monitor Parkinson’s.
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“Not only is the test quick, simple and painless but it should also be extremely cost-effective because it uses existing technology that is already widely available,” said the professor.
“We are now looking to take our findings forwards to refine the test to improve accuracy even further and to take steps towards making this a test that can be used in the NHS and to develop more precise diagnostics and better treatment for this debilitating condition.”
Parkinson’s can be difficult to diagnose / Image: Pixabay
Parkinson’s UK analysis suggests that 1 in 37 people will be diagnosed with Parkinson’s in their lifetime.
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The onset of the disease – which sees the sufferer develop a range of physical symptoms such as tremors and stiff, slow movements – is often gradual; worsening over a period of months and years.
The condition can be difficult to diagnose, too.
In a recent survey of more than 2,000 people with Parkinson’s, more than a quarter revealed they were initially misdiagnosed with a different condition.
It took four years for Daxa Kalayci, 56, to be given an accurate diagnosis of Parkinson’s.
“Despite my diagnosis eventually being confirmed by a DaTscan, a quick and simple diagnostic test for Parkinson’s would have given me the chance to start my treatment earlier and enjoy life a lot more,” said Daxa.
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“But instead, I lost so many years not being able to pursue a career as a paramedic or go back to nursing.
“This test could be a game-changer for people living with Parkinson’s and searching for answers like I was.”
Professor David Dexter, Associate Director of Research at Parkinson’s UK said that two more people in the UK are diagnosed with Parkinson’s every hour – and the COVID-19 pandemic has increased complications with regards to delays and misdiagnoses.
However, he called the new results “significant” in the bid to revolutionise Parkinson’s treatment.
The Professor added: “With this innovative test, we could see people being diagnosed quickly and accurately enabling them to access vital treatment and support to manage their Parkinson’s symptoms sooner.”
News
Manchester United reject offers for Mason Greenwood as rep says he ‘should be allowed to move forward with his young life’
Danny Jones
Manchester United have reportedly rejected a number of offers for Mason Greenwood as the club continues their internal investigation into his behaviour.
The club have reportedly received a number of offers for the young forward from Turkish teams in recent weeks and months while Greenwood has been suspended from playing or training. He has yet to return to the sport after charges of attempted rape, controlling and coercive behaviour and assault occasioning actual bodily harm were dropped.
The charges handed down in January 2022 were ultimately dropped last month when key witnesses withdrew, more than a year on from the incident that was widely circulated on social media.
Now, following a behind-the-scenes feature by The Athletic and ‘new material’ leading the Crown Prosecution Service to drop the case for the foreseeable, it seems United are now the only party still investigating Greenwood, with his own team and figures around the club pushing for a resolution.
▪️ Police spoke to #MUFC about Greenwood during lockdown ▪️ Senior staff offered guidance but no specialists brought in ▪️ Man United have rejected offers from Turkish sides as internal investigation continues
— The Athletic | Football (@TheAthleticFC) March 27, 2023
Speaking to Laurie Whitwell as part of the piece, one of Greenwood’s representatives argued that there is “no real substance” to the allegations, them “a mix of old news, speculation, half-truths and completely untrue claims.”
He went on to say, “Mason is 21, he has been cleared and should be allowed the opportunity to rebuild and move forward with his young life.”
Another source is also said to have told the outlet that the youngster has been fundamentally changed by the experience, insisting that he “would run through a brick wall” to be back playing at United.
As for the club’s stance, it remains to be seen what their final decision on his future will be, but it was reported earlier this month that a potential return is still “firmly under consideration” and his number 11 shirt has not yet been vacated as many would have expected if he was set to move on.
His potential ‘phased return’ could include everything from therapy to a TV interview.https://t.co/DTisidvpRr
On the other hand, the article goes on to detail questions surrounding Greenwood’s conduct and general attitude during his relatively short time as a senior player too, the suggestion being that he was slacking in training because “he knew he was a good player”.
His attendance at Carrington is said to have been raised as an issue on more than one occasion and then-manager Ole Gunnar Solskjær often covered for training sessions and games he missed after failing to turn up to the team hotel for “unexplained absences”.
Another source who watched him play aged just 16 also went on to reveal that Bradford-born academy product “wasn’t shy about telling someone they were s***”, apparently even calling out Cristiano Ronaldo as “dead [finished]” when he was still at Real Madrid.
Greenwood played over 100 senior games for United and was widely considered one of the brightest young prospects in England, let alone the club, but the career trajectory he looked to be on is widely different from the problematic position he finds himself in now, regardless of any offers from abroad.
Led By Donkeys fool MPs into revealing ridiculous £10,000 daily rate in fake job interviews
Danny Jones
British political campaign group, Led By Donkeys, have once again taken aim at the Conservative government, managing to fool multiple MPs by putting them through fake job interviews.
The campaigners hatched the plan to see just how easy it is to ‘hire an MP’, with Tory politicians having been criticised for earning an additional £15.2 million in added income from ‘second jobs’ since 2019 alone — that’s on top of their already £80k-a-year salaries, of course.
So, after setting up a fake consultancy firm based out of Seoul, South Korea called Hanseong Consulting and inviting along a number of MPs, many of whom either previously held or currently sit in senior party positions, they began holding Zoom interviews with the various candidates to see if they’d be interested.
More importantly, however, the crucial question was “how much would they want to be paid?”. The likes of former Matt Hancock and Kwasi Kwarteng had very simple but nevertheless astounding answers:
🚨MPs FOR HIRE: a Led By Donkeys undercover investigation🚨
As you can see in the trailer for the full mini-documentary, both the former health secretary and the ex-Chancellor of the Exchequer quoted their day rate as up to £10,000.
In fact, Hancock broke down his figures even further, insisting that an hourly rate would equate to “around £1,500”. Wonder how that sizes up to the fee he was paid to be on I’m A Celeb? (yes, that wasn’t a fever dream, it really happened). We’ll let you do the nauseating maths on that one.
Other Tories who were duped into putting themselves forward for the made-up job included Gavin Williamson, Stephen Hammond and the Chairman of the party’s 1922 Committee (a private members group known to influencers backbenchers), Sir Graham Brady.
Well, they were the only ‘candidates’ to have issued statements after the fact trying to play down the story, anyway. The campaigners approached 20 different MPs under the guise of the fabricated company, with other individuals dropping out in more preliminary stages.
After having asked for £60k a year on top of his £48k annual salary as the representative for Manc constituency Altrincham and Sale West, this would have been Brady’s fourth job besides his two marketing and comms advisory roles, but assured he would always act “within the Code of Conduct”.
Hammond had more to say on the matter, responding that “scamming is an unpleasant activity undertaken with malicious intent”, while Hancock’s office responded by labelling it a “failed attempt at entrapment” and insisted he is free to look at “exploratory options” as he is set to stand down as an MP.
Led By Donkeys are now in the process of gradually releasing each one of the fake job interviews in full on their YouTube channel.
The Manc -
11th March 2021 
