A groundbreaking new drug has been approved on the NHS, and it could benefit hundreds suffering from one of the most aggressive forms of breast cancer.
It’s been revealed this week that NHS bosses have struck a deal with the manufacturers of the drug pembrolizumab, and have now been given the greenlight to treat around 1,600 patients in England who are suffering from triple negative breast cancer – which is one of the rarest and most aggressive forms of the disease.
Triple negative breast cancer accounts for around 15% of all cases, and is responsible for a quarter of all breast cancer deaths.
According to the charity Breast Cancer Now – which promotes cancer research, and offers support to sufferers – triple negative breast cancer is a particularly common form in those under 40, black women, and those who have inherited the BRCA gene.
Triple negative breast cancer patients have a shorter survival time than those with other forms of the disease, and typically, the risk of it returning and spreading to other parts of the body in the first few years after treatment is higher than for other cancer suffers.
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But now, scientists say that for those taking the new drug – which is a form of immunotherapy, and will be used alongside chemotherapy before surgery – the likelihood that the cancer will disappear, and the time before cancer returns, will increase.
Pembrolizumab will be one of just a few treatments that currently exist for triple negative breast cancer.
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Up to 1,600 of those affected by high risk triple-negative breast cancer a year are set to benefit from access to the treatment, called pembrolizumab, on the NHS.
Amanda Pritchard, the chief executive of NHS England, said the rollout of pembrolizumab – which she called “an innovative, potentially life-saving treatment” – was “fantastic news”, and said that it represented “a hugely significant moment for women”.
“It will give hope to those who are diagnosed and prevent the cancer from progressing, allowing people to live normal, healthy lives,” she added.
Breast Cancer Now has also hailed the approval of the new treatment.
“This new treatment can potentially lead to any detectable cancer disappearing by the time of surgery, meaning patients will then possibly face less invasive, breast-conserving surgery,” said Baroness Delyth Morgan, chief executive of Breast Cancer Now.
“By significantly reducing the likelihood of breast cancer recurring or spreading to other parts of the body where it becomes incurable secondary breast cancer, this treatment brings precious hope of more lives potentially being saved from this devastating disease.”
Victim named and murder investigation launched after young woman is killed in Newton Heath stabbing
Emily Sergeant
The victim of a street stabbing in Newton Heath this week has been named for the first time as a murder investigation continues.
It comes after officers from Greater Manchester Police (GMP) responded to reports of a disturbance at around 2am yesterday (Thursday 15 October) on Dorking Avenue, in the Newton Heath area of Manchester, and when they arrived on the scene, they found a woman in her 20s with serious injuries that were ‘consistent with a stabbing’.
Despite best efforts of all emergency services involved, the young woman was sadly pronounced dead at the scene.
As the murder investigation progresses, the woman has now been publicly named and a photo of her has been released for the first time.
She has been named as 26-year-old Alisha Samuels.
At this time, one man, aged 25, has been arrested on suspicion of murder, and a man and woman, aged 61 and 38, have been arrested on suspicion of assisting an offender, and they all remain in custody – with officers continuing their enquiries to establish the full circumstances of this incident.
Alisha’s family have asked for privacy whilst they deal with the devastating loss of their loved one, GMP has stated.
“We are continuing to urge people who may have information in relation to this incident to please come forward to support our investigation and bring justice for Alisha,” the police force said in a public appeal.
Anyone who may have witnessed the incident, or has mobile phone, CCTV, or doorbell footage, is urged to call GMP on 0161 856 5464, or contact them via the Major Incident Public Portal here.
Alternatively, you can contact Crimestoppers on 0800 555 111
Featured Image – GMP (Family Handout)
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Former supply teacher jailed for multiple upskirting and AI sex offences across Greater Manchester
Emily Sergeant
A former supply teacher has been jailed for multiple upskirting and AI sex offences in schools across Greater Manchester.
Abusali Rahman – a British national of Bangladeshi ethnicity from Salford – appeared in Bolton Crown Court this week for his sentencing after first being charged with, and then pleading guilty to, several offences.
The offences are including, but not limited to, 12 counts of taking an indecent photograph/pseudo-photograph of a child (images obtained by upskirting), three counts of making indecent photograph / pseudo-photograph of a child (making AI-generated images), and one count of attempting to meet girl under 16 following sexual grooming.
The offences are alleged to have taken place between December 2023 and June 2025, according to Greater Manchester Police (GMP).
Twelve girls have been identified in relation to the upskirting offences – aged between 13 and 16 at the time of the alleged offending – at seven high schools in three Greater Manchester boroughs (Bury, Bolton, and Salford).
GMP says it has remained in close contact with the schools, local authorities, and other partners throughout the investigation to ensure all appropriate support is in place for those who need it.
Additionally, the court also heard how Rahman amassed a collection of images of young girls, using AI and other methods to sexualise them.
The images numbered more than 300 in total, ranging from Category A to Category C classifications, and Rahman would post these on social media, often alongside humiliating and disgusting captions.
Rahman was sentenced to six years in prison, and will also be subject to a 20-year Sexual Harm Protection Order.
A former supply teacher has been jailed for child sex offences in schools across Greater Manchester / Credit: GMP
Detective Constable Lisa McGaffin, from GMP’s Bolton Child Protection Team, described Rahman’s crimes as ‘absolutely abhorrent’.
“My thoughts throughout this process have always been with the young girls who have been subject to such indignity,” DC McGaffin said following the sentencing this week. “Their welfare and support will always be a priority for us.
“While working as a teacher – someone who young children should trust and be safe with – Rahman repeatedly took secret photos for his own sick gratification, before posting images online which showed his total disregard for the girls’ respect and dignity.
Emily Sergeant -
8th November 2022 
