A groundbreaking new drug has been approved on the NHS, and it could benefit hundreds suffering from one of the most aggressive forms of breast cancer.
It’s been revealed this week that NHS bosses have struck a deal with the manufacturers of the drug pembrolizumab, and have now been given the greenlight to treat around 1,600 patients in England who are suffering from triple negative breast cancer – which is one of the rarest and most aggressive forms of the disease.
Triple negative breast cancer accounts for around 15% of all cases, and is responsible for a quarter of all breast cancer deaths.
According to the charity Breast Cancer Now – which promotes cancer research, and offers support to sufferers – triple negative breast cancer is a particularly common form in those under 40, black women, and those who have inherited the BRCA gene.
Triple negative breast cancer patients have a shorter survival time than those with other forms of the disease, and typically, the risk of it returning and spreading to other parts of the body in the first few years after treatment is higher than for other cancer suffers.
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But now, scientists say that for those taking the new drug – which is a form of immunotherapy, and will be used alongside chemotherapy before surgery – the likelihood that the cancer will disappear, and the time before cancer returns, will increase.
Pembrolizumab will be one of just a few treatments that currently exist for triple negative breast cancer.
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Up to 1,600 of those affected by high risk triple-negative breast cancer a year are set to benefit from access to the treatment, called pembrolizumab, on the NHS.
Amanda Pritchard, the chief executive of NHS England, said the rollout of pembrolizumab – which she called “an innovative, potentially life-saving treatment” – was “fantastic news”, and said that it represented “a hugely significant moment for women”.
“It will give hope to those who are diagnosed and prevent the cancer from progressing, allowing people to live normal, healthy lives,” she added.
Breast Cancer Now has also hailed the approval of the new treatment.
“This new treatment can potentially lead to any detectable cancer disappearing by the time of surgery, meaning patients will then possibly face less invasive, breast-conserving surgery,” said Baroness Delyth Morgan, chief executive of Breast Cancer Now.
“By significantly reducing the likelihood of breast cancer recurring or spreading to other parts of the body where it becomes incurable secondary breast cancer, this treatment brings precious hope of more lives potentially being saved from this devastating disease.”
Major pop star crowns humble rice and three cafe as ‘Jewel of Manchester’ ahead of sold-out gig
Thomas Melia
A beloved city centre takeaway has been given the title of ‘Jewel of Manchester’ by chart-topping UK singer Sam Smith.
Known for hits like ‘Stay With Me’, ‘I’m Not The Only One’ and more recently ‘Unholy’, UK pop-ballad act Sam Smith also likes to drop a food review every once in a while.
Currently on the road with a run of shows in Manchester and London for their ‘To Be Free’ live shows, Sam Smith is stopping off at some of our city’s much-loved spots.
On their food-reviewing account titled ‘Sam Served’, where they adopt the aptly-fitting nickname ‘Ham Smith’, Sam has visited restaurants across the globe – and most recently turned their attention to Manchester’s own This & That.
Smith decided to pop in and grab a cheeky rice and three from long-standing backstreet food business This & That, and it certainly went down a treat.
After sampling their amazing selection of meat, vegetable and vegan curries, the musician crowned this family-run Indian takeaway a ‘Jewel of Manchester’.
The hitmaker described this Northern Quarter Indian eatery as ‘Everything food should be’ and definitely enjoyed all the curries on offer ‘leaving belly and heart full’.
This & That prides itself on affordable and comforting food with its ‘Rice and Three Curries’ starting from just £6 – not bad for a city centre foodie spot.
Sam has racked up an impressive 490k followers via their ‘Sam Served’ profile, with famous faces like Lily Allen, Denise Welch and CMAT all wanting to know the superstar’s foodie thoughts.
After enjoying a curry or three, Sam Smith also made sure to feed their soul to by venturing down to Afflecks and getting lost in the music at Mars Tapes.
Recognised as one of the UK’s only cassette and tape shops, Mars Tapes lets you flick through their crates of physical media and even preview tracks before you buy with its dedicated listening areas.
It’s safe to say that Smith has ‘Latched’ onto Manchester’s independent business scene and we’re here for it.
The London-born artist has just released their latest album Hazel Eyes and is currently amid a UK residency tour with two dates in Manchester’s Albert Hall and eight shows set for London Coliseum.
24-hour bus services are now running across all Greater Manchester boroughs
Emily Sergeant
24-hour bus services are now running across all boroughs in Greater Manchester.
You may remember that back in March, it was announced that every borough of Greater Manchester was set to get a night bus service in what is hoped to be a ‘boost’ to the night-time economy… and now it’s official, Transport for Greater Manchester (TfGM) has launched those 24-hour buses this month, along with a series of other measures.
Oldham, Stockport, Tameside, and Trafford now join the rest of Greater Manchester in having 24-hour bus services, meaning every part of the region will have a night bus operating Thursday through to Sunday.
It’s expected that these new services will help around 625,400 people working in the night-time economy across Greater Manchester, as well as those out enjoying the region’s nightlife, TfGM has said.
The routes which will run around the clock from Thursday until Sunday are:
50 (Salford – Manchester)
216 (Tameside – Manchester)
263 (Trafford – Manchester)
192 (Stockport – Manchester)
83 (Oldham – Manchester)
All Greater Manchester boroughs now have 24-hour bus services / Credit: TfGM
They launch alongside the most significant service changes to the Bee Network since the completion of bus franchising last year – including other new bus routes, and more frequent services across Greater Manchester.
“We want everyone to be able to enjoy everything Greater Manchester offers, without the worry of how to get there and get home,” commented Greater Manchester Mayor, Bev Craig.
“By growing the Bee Network, we’re making it easier than ever for people to use the bus, day and night.
“Our night buses are already providing a lifeline to some of the hundreds of thousands of people who are growing our night-time economy and working in essential public services.”
“Whether people are heading home from a night at the theatre or starting the early shift at a hospital, they can now get on board the night bus as a safe and affordable way to travel.”
Further improvements will delivered from January 2027, and a full breakdown by borough can be found on the Bee Network website here.