A groundbreaking new drug has been approved on the NHS, and it could benefit hundreds suffering from one of the most aggressive forms of breast cancer.
It’s been revealed this week that NHS bosses have struck a deal with the manufacturers of the drug pembrolizumab, and have now been given the greenlight to treat around 1,600 patients in England who are suffering from triple negative breast cancer – which is one of the rarest and most aggressive forms of the disease.
Triple negative breast cancer accounts for around 15% of all cases, and is responsible for a quarter of all breast cancer deaths.
According to the charity Breast Cancer Now – which promotes cancer research, and offers support to sufferers – triple negative breast cancer is a particularly common form in those under 40, black women, and those who have inherited the BRCA gene.
Triple negative breast cancer patients have a shorter survival time than those with other forms of the disease, and typically, the risk of it returning and spreading to other parts of the body in the first few years after treatment is higher than for other cancer suffers.
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But now, scientists say that for those taking the new drug – which is a form of immunotherapy, and will be used alongside chemotherapy before surgery – the likelihood that the cancer will disappear, and the time before cancer returns, will increase.
Pembrolizumab will be one of just a few treatments that currently exist for triple negative breast cancer.
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Up to 1,600 of those affected by high risk triple-negative breast cancer a year are set to benefit from access to the treatment, called pembrolizumab, on the NHS.
Amanda Pritchard, the chief executive of NHS England, said the rollout of pembrolizumab – which she called “an innovative, potentially life-saving treatment” – was “fantastic news”, and said that it represented “a hugely significant moment for women”.
“It will give hope to those who are diagnosed and prevent the cancer from progressing, allowing people to live normal, healthy lives,” she added.
Breast Cancer Now has also hailed the approval of the new treatment.
“This new treatment can potentially lead to any detectable cancer disappearing by the time of surgery, meaning patients will then possibly face less invasive, breast-conserving surgery,” said Baroness Delyth Morgan, chief executive of Breast Cancer Now.
“By significantly reducing the likelihood of breast cancer recurring or spreading to other parts of the body where it becomes incurable secondary breast cancer, this treatment brings precious hope of more lives potentially being saved from this devastating disease.”
Full list of road closures set to be in place for Manchester Day 2024
Emily Sergeant
Manchester Day is back for 2024 this weekend, and the full list of road closures set to be in place has been confirmed.
Now that schools are officially out across Greater Manchester, and the summer holidays are well and truly here, the hugely-popular Manchester Day is making a return once again this Saturday 27 July, and as always, it’s set to be “the day summer officially starts” in the city centre – with a massive celebration of “all things Mancunian” on the cards.
The theme of this year’s annual event is ‘Let The Games Begin’, and it’s inspired by the international summer of sport, just 2024 Olympics kicks off over in Paris.
The day will be packed full of free events and activities to get involved with.
Some city centre roads will be closed on Friday 26 and Saturday 27 July for Manchester Day.
These will include:
🛣️Deansgate 🛣️St Ann Street 🛣️St Mary’s Gate 🛣️Market Street 🛣️King Street
— Manchester City Council (@ManCityCouncil) July 21, 2024
But of course, in order for the all the fun to go ahead as safely as possible, and as tends to be the case for events like these, Manchester City Council says it will need to make some temporary road closures to facilitate it.
The full list of road closures has now been confirmed by the Council, and there’s some major city centre thoroughfares set to be out of action.
Here’s everything you need to know.
Manchester Day is back for 2024 to celebrate the international summer of sport / Credit: Manchester City Council
Manchester Day 2024 – Road Closures
Saturday 27 July
From 6am to 11:59pm, Manchester City Council has confirmed that the following roads will be closed:
Deansgate (Manchester Cathedral to John Dalton Street) – access will be maintained to Marks and Spencer’s car park and Number One Deansgate.
St Ann Street (Deansgate to Cross Street)
St Mary’s Gate (Exchange Street to Deansgate)
St Mary’s Street (Southbridge Street to Deansgate)
Market Street (Exchange Street to Cross Street)
Fennel Street (Corporation Street to Cathedral Street) – access will be maintained for morning deliveries only.
Cathedral Street (Fennel Street to Exchange Square) – access will be maintained for morning deliveries only.
Cateaton Street (Exchange Square to Deansgate)
Barton Square (St Ann’s Square to St Ann Street)
King Street (Cross Street to Deansgate) – no access for deliveries.
All accessible bays, bus lanes, and taxi ranks within the closed areas will also be suspended during from 6pm on Friday 26 July to 11:59pm on Saturday 27 July.
The parking suspensions set to be in place are:
Deansgate (Manchester Cathedral to John Dalton Street)
St Ann Street – including the bays outside St Ann’s Church (Deansgate to Cross Street)
St Mary’s Gate (Exchange Street to Deansgate)
St Mary’s Street (Southbridge Street to Deansgate)
Southgate (St Mary’s Street to King Street West)
Market Street (Exchange Street to Cross Street)
Fennel Street (Corporation Street to Cathedral Street) – access will be maintained for morning deliveries only.
Cathedral Street (Fennel Street to Exchange Square) – access will be maintained for morning deliveries only.
Cateaton Street (Exchange Square to Deansgate)
Victoria Street (Cathedral Approach to Deansgate)
Todd Street (Corporation Street to Station Approach)
King Street (Spring Gardens to Southgate)
South King Street (Ridgefield to Deansgate)
Barton Square (St Ann’s Square to St Ann Street)
King Street West (Deansgate to St Mary’s Parsonage)
St James’s Square (John Dalton Street to South King Street)
Cross Street (King Street to Corporation Street)
Museum Street (Peter Street to Windmill Street)
Marsden Street (Cheapside to Brown Street)
Manchester Day 2024: Let The Games Begin! will take over the city centre on Saturday 27 July from 12pm-6pm.
Check out everything you need to know ahead of the event here.
‘Complex’ Metrolink repairs to the Rochdale via Oldham line could take weeks to complete
Emily Sergeant
Work currently underway on the Rochdale via Oldham line is expected to take several weeks to complete.
Transport for Greater Manchester (TfGM) has confirmed that land movement affecting the Metrolink network near Derker has now “slowed”, and this means that detailed ground investigations and temporary repair works have been able to get underway.
In order for trams to run again on the crucial line from the city centre to the two major Greater Manchester towns, TfGM says that a small section of track has to be moved back – also known as ‘slewed’ – into its original position.
The overhead line poles also need to be repaired too, the transport operator revealed.
Rochdale line update
Land movement affecting the Metrolink network near Derker has slowed, enabling detailed ground investigations and temporary repair works to get underway.
To get trams running again, a small section of track has to be moved back into its original position… pic.twitter.com/byERjitdi1
Unfortunately though, due to the “complex” nature of these works, and despite the fact that TfGM says it’s actively looking to “accelerate” the repairs, the project is expected to take up to five weeks to complete in full.
On top of this, the detailed ground investigations will also establish whether any further work to strengthen foundations beneath the track will be needed at a later date.
TfGM has apologised for the inconvenience caused to passengers.
‘Complex’ Metrolink repairs to the Rochdale via Oldham line could take weeks to complete / Credit: TfGM
Speaking on the scale of works currently underway, and how long he expects them to continue for, Pete Sommers, who is TfGM’s Network Director for Metrolink, said: “I’m sorry for the impact this is having, and will continue to have, on people’s journeys.
“We are working to get trams running through the area again, but this remains a complex and challenging issue and it could still be a few weeks before this happens.
“We will of course keep passengers updated, and I’d encourage people to check our social media channels and website for the latest information and advice.”
Emily Sergeant -
8th November 2022 
