On Monday, news filtered through that the vaccine being developed by Pfizer and BioNTech is 90% effective - with zero safety concerns raised during its testing phase during which it was used on 43,500 people.
The sensation of relief that swept the country on Monday was understandable.
During the afternoon, news filtered through that a vaccine being developed by Pfizer and BioNTech has been confirmed to be 90% effective – with zero safety concerns raised from its testing phase during which it was used on 43,500 people.
This is as close as we’ve been to the prospect of immunisation since the pandemic took hold.
Chief Medical Officer Chris Whitty called the news “very encouraging”, whilst Deputy CMO Jonathan Van-Tam even suggested there could be a vaccine by Christmas – with a “much better horizon by spring.”
But the truth is these are early days.
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Prime Minister Boris Johnson – who himself must have been buoyed by the very real prospect of a magic jab after a torrid few months leading the nation – urged caution.
He warned it was still “very, very early days”, and that “the biggest mistake we could make now would be to slacken our resolve at a critical moment.”
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Van Tam also admitted that setbacks during the distribution of a vaccine could easily happen, and attempted to clarify the situation with a football analogy.
“[We] haven’t won the cup yet, but what it does is it tells you that the goalkeeper can be beaten,” he said.
Here’s what we know about the new vaccine so far…
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How does the vaccine work?
The Pfizer and BioNTech vaccine works by teaching the immune system to combat coronavirus.
Two doses are required – three weeks apart – for maximum effect.
The vaccine involves injecting people with a tiny bit of the virus which the immune system immediately recognises as a threat and learns how to defeat; thereby offering future protection.
According to developers, 9 out of 10 people who receive the vaccine will not get COVID symptoms.
Who will get it first?
The most vulnerable people in the UK will have first dibs on any vaccine.
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This means it’s likely to be distributed to care homes and hospitals – locations the virus has hit hardest.
Frontline workers may also be prioritised for doses.
The expectation is that the older you are, the sooner you will be eligible for the coronavirus vaccine.
Younger people are likely to be lower down the list unless they have a condition that categorises them as vulnerable.
Will it work?
It does, so far.
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But the answer as to whether the vaccine will work in the long-term is a case of wait and see.
There are apparently some logistical challenges to storing the vaccine, too – with doses having to be kept at -80 degrees (facilities a humble GP surgery or pharmacy would not have).
The virus may also mutate later down the line, which would mean the vaccine would have to be tweaked in order to remain effective.
When will lockdowns stop?
Once the vaccine is ready, the challenge is getting it to the people who need it most.
This will take time, and until then, social restrictions remain of crucial importance in the fight against COVID-19.
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Is the UK getting the Pfizer and BioNTech vaccine?
Yes.
Britain has ordered 30 million doses.
What about other vaccines?
There are around a dozen vaccines in the final stages of development – with news expected on these in the coming weeks and months.
However, the Pfizer vaccine appears to be the lead candidate.
The BBC’s Health and science correspondent, James Gallagher, stated: “We are still waiting for the full data, but these results are even better than people were hoping for.
“A good flu vaccine protects around half of people, so 90% at the first attempt is a triumph.”
News
Pep Guardiola agrees new contract to stay at Manchester City for at least one more year
Danny Jones
Blues will be delighted to hear that Manchester City manager Pep Guardiola is staying after agreeing to sign a contract extension that will keep him at the club for at least one more year.
The Catalan coach and supremely talented tactician has won all there is to win with Man City and after completing not only a record-matching treble but making history by becoming the first English team to win four Premier League titles in a row, you could argue his Etihad project is well and truly completed.
Guardiola, who joined City back in 2016, has gradually been creeping towards the end of his most recent contract, leaving those slowly searching for his replacement and the fan base wondering what the future holds for their next chapter.
But it turns out they don’t have to worry about life after Pep for a little while longer, as the 53-year-old has now extended his stay for at least another season. The blue moon that has loomed over Manchester for the best part of a decade isn’t going anywhere just yet.
𝗘𝘅𝗰𝗹𝘂𝘀𝗶𝘃𝗲: Manchester City manager Pep Guardiola has agreed a new one-year contract extension with the option of an additional year.
The 53-year-old’s existing City deal was due to expire at the end of this season and, if the new terms are fulfilled, it would take… pic.twitter.com/S8r1gVEcPj
Breaking the news on Tuesday evening, 19 November, The Athletic‘s Sam Lee revealed that Pep Guardiola will remain head coach for another season after agreeing to a new one-year deal.
The former Barcelona and Bayern Munich manager, who is comfortably one of the most decorated and celebrated coaches in football history, was due to leave the club at the end of the current campaign.
However, although his contract would have seen him depart by June of next year, this new deal will now see him stay in post until the summer of 2026, which will talk his tenure to a full 10 years.
Although City themselves are yet to confirm the signing amid the international break, it’s only a matter of time before they deliver the news all Blues have been waiting for – news that will no doubt come as a huge relief given the immense success he has brought to East Manchester.
Despite waiting until now to seemingly decide his future, the man himself has actually been pretty clear on the matter, insisting that he “fell in love” with the club from the moment he got here and saying as far back as 2020 that “unless they [CFG] sack me, I will stay here.”
Man City fans will honour Pep with a banner which reads in Catalan, 'we want you to stay'…
"They'll have to bring me the bill. I will pay the bank. I don't want them to spend money for that reason. I feel in love since the first day I came here." 🥺
Better still, while the details of the agreement are yet to be fully detailed, the report says that his new contract also includes the option to extend for a further year beyond that, meaning we could be looking at Pep in the dugout until 2027.
Should City go on to close the gap on current league leaders Liverpool, it would mean Guardiola would have overseen five title wins with the same team in a row: a feat only matched by very few in European football, most notably Juventus and Bayern Munich, the latter having managed 13 consecutive years.
Who knows if/when Guardiola will actually leave the Etihad Stadium for a new challenge, all we know is he changed modern football forever and has given Manchester – a city already spoilt in this respect – some of the most impressive football it’s ever seen.
All we do know is that the beautiful game’s passionate, bald, tiki-taka extraordinaire known simply as Pep is staying in 0161 for the time being and there are countless fans who are absolutely buzzing about it.
‘Shocking’ images taken with AI camera of drivers using mobiles and not wearing seatbelts released
Emily Sergeant
Thousands of people in Greater Manchester have been caught using mobile phones while driving or not wearing their seat belts.
Images captured by the state-of-the-art ‘Heads Up’ camera system – which uses a combination of artificial intelligence (AI) and human reviewers – as part of a trial in Greater Manchester, show drivers holding mobile phones in front of their face, to their ear while behind the wheel, and sometimes with passengers next to them.
According to Transport for Greater Manchester (TfGM), in several cases, the cameras also found drivers and passengers, both passengers and children, not being securely fastened in their seats or not wearing seat belts at all.
The trial aims to detect drivers who are potentially breaking the law and putting themselves, their passengers, and other road users, at risk.
AI is used as the first filter in a bid to ensure privacy for “the vast majority of law-abiding motorists” while also checking hundreds of thousands of vehicles over an intermittent period, TfGM explained – something which would likely take a human reviewer several months to complete.
Images containing “evidence of an offence” then go through a two-stage human check to confirm that an offence has taken place.
Any offences detected as part of the trial were then passed on to Greater Manchester Police (GMP) to consider for further action, however if no offence was committed, the image was immediately deleted by the software.
More than 3,200 people have been caught using mobile phones while driving or not wearing seat belts as part of a trial of state-of-the-art cameras in Greater Manchester.
— Safer Roads Greater Manchester Partnership (@SaferRoadsGM) November 19, 2024
The trial – which was carried out by AECOM and Acusensus, on behalf of Safer Roads Greater Manchester – was held across the region throughout September and October to “gather data” and “understand the scale of the issue” to inform future education campaigns and enforcement.
It comes after it was revealed that nearly 10,000 people who live in, work in, or visit Greater Manchester have been killed or seriously injured on our roads over the last decade.
During the deployment, the ‘Heads Up’ system recorded 812 drivers distracted by using mobile phones behind the wheel, and 2,393 incidents of seat belt non-compliance by drivers or passengers.
As it stands, no offenders have yet been prosecuted from this trial, TfGM confirmed.