The NHS is launching the world’s biggest trial of a potentially life-saving blood test that can detect more than 50 types of cancer.
The Galleri test – which is already available in the US – can detect cancers that are not routinely screened for, and it can find where the disease is coming from in the body with a high degree of accuracy.
It looks for chemical changes in fragments of genetic code that leak from tumours into the blood – something done by some cancers long before symptoms even appear.
Around 140,000 volunteers in eight areas of England will be recruited to try the Galleri test.
The eight areas involved in the trial will be right here in Greater Manchester, as well as Cheshire and Merseyside, the North East, West Midlands, East Midlands, East of England, Kent and Medway, and southeast London.
The NHS trial – which is being led by the Cancer Research UK and King’s College London Cancer Prevention Trials Unit, together with Grail that developed the Galleri test – will invite people from different backgrounds and ethnicities who are aged between 50 and 77 to take part, providing they have had a cancer diagnosis in the last three years.
Blood samples will be taken at mobile testing clinics across the eight areas over the coming weeks, in 12 months’ time, and again in two years.
The first results are expected by 2023 and, if successful, the test could be in use from 2024.
Today the NHS launches the world’s largest trial of a revolutionary blood test which detects over 50 types of cancer before symptoms appear.
The test is said to have been especially effective at finding cancers that are more difficult to identify early, such as head and neck, bowel, lung, pancreatic, and throat cancers – but it cannot detect all cancers.
For this reason, it would not replace NHS screening programmes such as those for breast, cervical, and bowel cancer.
The NHS said the test could play a major part in the health service’s ambition to catch 75% of cancers at an early stage, which is when they are easier to treat.
Speaking as the test trial launches, Amanda Pritchard – Chief Executive at the NHS – said: “This quick and simple blood test could mark the beginning of a revolution in cancer detection and treatment here and around the world.
“By finding cancer before signs and symptoms even appear, we have the best chance of treating it and we can give people the best possible chance of survival.”
Around 140,000 volunteers in eight areas of England will be recruited to try the Galleri test / Credit: WallpaperFlare
Professor Peter Sasieni – director of the unit and one of the trial’s lead investigators – added: “The test could be a game-changer for early cancer detection and we are excited to be leading this important research.
“Cancer screening can find cancers earlier when they are more likely to be treated successfully, but not all types of screening work.”
Featured Image – Pxfuel
News
A long-standing Italian restaurant in Trafford has sadly announced its imminent closure
Danny Jones
Another day, another bit of unfortunate hospitality news, as long-standing Greater Manchester restaurant, Little Italy in Timperley, has announced it is closing permanently very soon.
The Trafford favourite, which has been serving locals for nearly 20 years, has informed regular diners that it will sadly be closing its doors for good, with Little Italy’s final service set for later this month.
Having earned plenty of praise in its time, including being one of the few spots in and around the Altrincham area to have won a TripAdvisor Certificate of Excellence in 2015, before the borough saw its foodie boom begin.
But fast forward a decade, and the Timperley institution is yet another culinary casualty to be confirmed of late, with Little Italy sharing a tear-jerking statement online.
Sharing the tragic news on social media this Friday (5 Sep), the restaurant wrote: “To all our lovely customers, it is with a heavy heart that we share some news with you all. After over 18 years of serving you all in Timperley, we will be closing our doors later this month.
“This has not been an easy decision. Unfortunately, rising costs and a significant increase in rental [costs] have made it impossible to continue in a sustainable way. As much as we love what we do, the reality is that it has become too difficult to maintain under these circumstances.
“Over the coming weeks, we will continue to cook with love and serve with the same passion as always. We would love to see you all and share one more meal, and raise a glass together.”
Safe to say that the post has been met with an outpouring of condolences and support from natives nearby and those who have travelled to enjoy their food.
Little Italy went on to add that they will detail more about their final week of business as soon as possible.
They can’t be accused of not keeping up with times and not trying to promote via social media either, as they small family-run team – headed up by Sam Cauchi, who bought the site back in 2008 – have always given things a go besides the day-to-day operation of the restaurant.
Being one of many saddened customers to respond underneath the announcement, we couldn’t possibly sum up things better than local Vanessa Nice, who said: “Look at all these amazing comments – you certainly made your mark as a home from home for the residents of Timperley.
“The end of an era will always be sad, but sometimes life and families have to move on.”
As for Cauchi and co., they signed off by simply adding: “From the bottom of our hearts, thank you for your support, kindness and friendship over the years. Timperley has been our home, and you have all been our family.
“Love from all the team at Little Italy.”
It goes without saying that we’re gutted for the gang and our thoughts are with everyone involved at this difficult time. For now, we can only say thank you to the countless Greater Manchester locations that continue to fall foul in the face of the rising pressures industry-wide. Case and point…
The bizarre explanation behind Manchester’s new mini ‘green space’ – that’s completely closed off
Danny Jones
One thing you always hear people who live in central Manchester calling out for is green space, but when a new patch of grass does arrive, you don’t exactly expect it to be completely inaccessible.
Just a quick FYI to those of you passionate about supporting what little nature there is left in our city centre: brace yourselves, as this one is rather annoying…
For anyone who’s walked down Whitworth Street West past the once lively Locks, or even got off at Deansgate–Castlefield tram stop and come down the glass stairs closest to the Albion Bridge, you may have noticed a rogue patch of grass surrounded by black fencing next to the City Road Inn pub.
It could be considered a nice little lawn were it not completely fenced off, but the question is, why has it popped up there? Well, local lad Curtis Rothwell has recently debunked the whole frustrating mess for us in a helpful video.
Yes, as explained by the Pre-Construction Manager who works for local utilities contractor Zenit Infrastructure Solutions Limited, the somewhat laughable but disheartening gated green space on Whitworth Street is essentially a feeble attempt at adhering to permission laws.
As detailed by Rothwell, the plot bought for a sizeable sum last year (only the original developers didn’t have the funding to actually pull off their initial plans) is now set to become student accommodation.
Currently, real estate firm Tri7 – which has now been fully folded into the parent group known as Fusion, as previous part-owners already – still has a hold on the land for now.
However, after being ordered by Manchester City Council to tidy up the area in the meantime, as they await planning permission to be fully approved, they decided to lay these new rolls of turf there.
Ok, so while the notion of the Council ordering a property company to make urban spaces look pretty and the idea of introducing more grassy zones into the city sound good on paper, as you can see, the real-life result doesn’t quite match up.
Not only does this feel like a bare minimum effort to appease the local authorities ahead of erecting yet another skyscraper, but more importantly, it feels like sheer nonchalant neglect and/or plain dismissal of those Manc residents crying out for more grass, nature and a break from the concrete jungle.
The fact that the rare green space is totally blocked by tall, almost authoritarian-feeling fences and sealed off by a big, black gate comes across like a casual two fingers to both the Council and those living in the city centre.
Speaking to The Manc, Curt commented: “It’s positive the council can take charge of how our empty spaces look after demolitions. In this case, maybe the demolition was carried out too early, which happens, but when it does, greenery is the best look they can give to local people.”
You can see the latest update on the planning permission HERE, and for now, if you’re looking for green spaces in Manchester, you’ll find them more frequently beyond the outskirts and heading into the boroughs; this one is strictly off limits. Find a whole bunch of ones that aren’t down below:
The Manc -
13th September 2021 
