Researchers are looking for participants to test a potential new treatment for OCD
Volunteers taking part will be reimbursed for their time (including reasonable travel costs) and may be offered the study medication free of charge for 48 weeks.
A leading clinical research organisation is running a clinical trial to test a potential new medication for people living with OCD.
According to the NHS, it is estimated that a quarter of a million people are living with OCD in the UK at some point in their lives, that’s equivalent to 12 in every 1,000.
This number increases drastically when we consider those who haven’t received a diagnosis who could be living with OCD symptoms and not receiving the professional support they may need or understand why they are experiencing intrusive thoughts.
Dr Alex Worthington, Clinical Research Physician at MAC Clinical Research, explains that “obsessive-compulsive disorder, commonly referred to as OCD, is a mental health condition with three main parts: obsessions, emotions, and compulsions.
For #OCDWeek, we wanted to highlight some statistics and information to raise awareness of #OCD.
If you have OCD and are having little to no response to your current antidepressant treatment, you may be eligible to take part in a clinical trial.
“Obsessions are persistent thoughts, images, doubts, worries, or urges that intrude on an individual’s mind, despite being unwanted.
“These thoughts can cause significant mental discomfort or anxiety. Some of the emotions felt due to intrusive thoughts can include guilt, depression, and disgust.
“Compulsions refer to repetitive behaviours that an individual engages in to temporarily alleviate the anxiety caused by the obsession. Examples of compulsions include checking if a door is locked multiple times or repeating certain phrases mentally.”
There’s a need for more effective treatment options for OCD, which is why award-winning clinical research organisation, MAC Clinical Research is conducting a clinical trial to test a potential new treatment that is hoped to reduce OCD symptoms and ultimately improve quality of life.
Here at MAC, our OCD clinical trial is open for people struggling with OCD symptoms.
Eligible participants will receive up to £490 plus reasonable travel expenses.
If you or someone you know has been living with OCD or OCD symptoms, and provided you meet the overall criteria, you could be reimbursed up to £490 for your time and participation in the clinical trial plus reasonable travel expenses.
If the treatment works, you may be able to receive nearly a year’s worth (48 weeks) of the medication free of charge as part of an open-label extension study.
You can find out more and register your interest HERE.
As explained in the summary for this clinical trial, “people with OCD tend to have signalling pathways in the brain which are overactive, causing intrusive thoughts, compulsive behaviour or other OCD symptoms.
“Previous clinical trials suggest that the study medication works to dampen down these overactive pathways which may help people with OCD when used in combination with their usual antidepressant medication.”
The study is expected to run for approximately five months. The trial itself will involve taking the oral medication or a placebo daily for ten weeks alongside seven visits to the clinic for check-ups to examine if your OCD symptoms improve and how well you are coping with taking the medication.
As part of International OCD Awareness Week, MAC also looked intohow the condition affects people in the workplace and answered some of the public’s pressing questions surrounding the disorder with one of the organisation’s leading psychiatrists, Dr David Gregory.
One of MAC’s leading psychiatrists sheds light on OCD treatment.
To ensure optimal safety, each study participant must meet a pre-determined set of eligibility criteria. To be eligible for the trial, you need to:
Be aged between 18-65
Have had OCD symptoms or an OCD diagnosis for at least 1 year that affects daily life.
Be taking an antidepressant for your OCD that isn’t fully helping.
To ensure optimal patient safety, participants must not have any of the following:
Bipolar, schizophrenia, autism, Tourette’s, or other psychiatric conditions
Diagnosed with an eating disorder.
Have diabetes that requires insulin.
Other criteria will apply.
If you want to learn more about MAC Clinical Research or if you’re considering being part of the clinical trial, you can learn more and register your interest by visiting their OCD research webpage.
For #OCDWeek, we wanted to share what some of our clinical trial participants said made them want to take part in OCD clinical research with MAC.
Featured Image — MAC Clinical Trial/The Manc Group
Sponsored
Nike and go-to online running shoe suppliers confirmed as new sponsors for Altrincham 10k
Danny Jones
The annual Altrincham 10k just got a whole lot bigger and better ahead of this year’s run, as the annual race has just notched Nike as one of their new lead sponsors – and that’s not all.
Alty’s annual race is also being backed by SportsShoes.com, a.k.a. the go-to trainers supplier for so many runners, who will be presenting the 2025 edition in partnership with RunThroughUK.
Now part of RunThrough North‘s regular programme, Altrincham 10k continues to grow in size with each passing year, as demonstrated by getting such prestigious sponsors on board.
Taking place this weekend, the 2025 Alty 10k could just be the biggest yet.
We are thrilled to announce that we are teaming up with @Nike & @sportsshoes_com to bring the town an unforgettable race day 🤝
📅 Sunday 7th September 🏃 3,500 runners 👟 Closed roads ⚡️ Electric atmosphere
Set to welcome approximately 3,500 runners to the Trafford market town’s central streets, the Altrincham 10k is one of the final large-scale running events on the local calendar.
Aligning both famous brands with the heart of Altrincham’s running community and, indeed, giving Greater Manchester’s wider sports culture, it’s yet more prestige for 0161.
The 2025 race will also see Nike showcase its latest road running line-up, including the newest max cushioning shoe: the ‘Vomero Plus’; the responsive ‘Pegasus’ everyday trainer, as well as supportive ‘Structure’ model, meaning runners will get a chance to sample their latest styles.
As well as support from SportsShoes.com and official Nike ambassadors, North West native and GB triathlete Katie Halligan, Hits Radio presenter and ultra runner Hattie Pearson, as well as local Manc artist Emma Evans will all be there too.
These equally inspiring women have also been chosen to help represent Nike and RunThrough’s shared mission of attracting more female runners, as shown with events such asthe recent 2025 Women’s Run Series back in April.
Co-Founder of RunThrough, Matt Wood, said of the new partnership: “Welcoming Nike as title sponsor of the Altrincham 10K, alongside our long-standing partner SportsShoes.com, is a huge milestone for the event.
“This partnership highlights the growth of our community and the strength of our brand. We can’t wait to support the thousands of runners taking part in the Nike Altrincham 10K, Presented by SportsShoes.com.”
As for SportShoes, brand manager Gavin Bannister added: “The energy around this year’s 10K will be electric, and we can’t wait to see everyone out there chasing their goals and celebrating the power of running.
“From our own athletes to first-time runners, this event is all about showing up, pushing limits, and being part of something truly special, and that is what Nike and Sportsshoes.com are all about.”
Entries are still open for any of those interested in a last-minute place in the race on Sunday, 7 September – you can sign up HERE.
Manchester’s largest outdoor ice rink is returning to the city centre this festive season
Emily Sergeant
Manchester’s massive outdoor ice rink has been confirmed for a return to Cathedral Gardens once again this festive season.
Skate Manchester has always been a festive staple of our city centre, and there’s also a flurry of other frozen events and activities planned for 2025 too – including the return of the Scare Skate for Halloween.
Following success in previous years, Scare Skate returns this spooky season, and families, friends, and festive fun seekers visiting the rink this season can expect Halloween-themed music, lighting, and themed props to ignite the fright factor.
After Halloween, the magic continues as the rink transforms into a festive wonderland.
Manchester’s largest outdoor ice rink is returning to the city centre this festive season / Credit: Supplied
Skaters can expect to glide across a gleaming ice path and spin around a dazzling seven-metre Christmas tree taking centre stage in the middle of the rink.
You’ll be able to enjoy the sights and sounds of Christmas whatever the weather has in store for our city this year too, as although the rink will be outdoors in the heart of Cathedral Gardens, the ice is fully covered.
The rink will also offer a variety of skate sessions tailored to meet the needs of all visitors, which includes dedicated quiet and toddler sessions designed for a more relaxed environment, along with discounted tickets and weekly events for students.
New this year is the Skate on and Skate off ‘Pit Lane’ available during skating for those needing a break and a hot chocolate or mulled wine, plus a VIP ticket option allowing for a fast-track entry into the rink.
Super early bird tickets are now available to buy / Credit: Supplied
Skate Manchester is also one of the most sustainable events in the UK, thanks to being partially powered by the grid.
“We’re proud to bring one of the top five largest ice rinks in the UK to Manchester once more, as part of our mission to create magical and sustainable winter events that will set the standard for winter attractions globally,” commented Rob Derry, who is the Director at Tamarisk Events, the company that coordinates the event.
“By being partially powered by the grid, Skate Manchester is one of the more environmentally responsible attractions of its kind, allowing visitors to enjoy the magic of skating with a lighter footprint.”
Skate Manchester will be returning to the city on Saturday 25 October and running right up until Sunday 4 January 2026, with super early bird tickets now available to get your hands on, and discounted family tickets and student night tickets also available.
You can find more information and to book tickets here.
Danny Jones -
16th November 2023 
