Researchers are looking for participants to test a potential new treatment for OCD
Volunteers taking part will be reimbursed for their time (including reasonable travel costs) and may be offered the study medication free of charge for 48 weeks.
A leading clinical research organisation is running a clinical trial to test a potential new medication for people living with OCD.
According to the NHS, it is estimated that a quarter of a million people are living with OCD in the UK at some point in their lives, that’s equivalent to 12 in every 1,000.
This number increases drastically when we consider those who haven’t received a diagnosis who could be living with OCD symptoms and not receiving the professional support they may need or understand why they are experiencing intrusive thoughts.
Dr Alex Worthington, Clinical Research Physician at MAC Clinical Research, explains that “obsessive-compulsive disorder, commonly referred to as OCD, is a mental health condition with three main parts: obsessions, emotions, and compulsions.
“Obsessions are persistent thoughts, images, doubts, worries, or urges that intrude on an individual’s mind, despite being unwanted.
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“These thoughts can cause significant mental discomfort or anxiety. Some of the emotions felt due to intrusive thoughts can include guilt, depression, and disgust.
“Compulsions refer to repetitive behaviours that an individual engages in to temporarily alleviate the anxiety caused by the obsession. Examples of compulsions include checking if a door is locked multiple times or repeating certain phrases mentally.”
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There’s a need for more effective treatment options for OCD, which is why award-winning clinical research organisation, MAC Clinical Research is conducting a clinical trial to test a potential new treatment that is hoped to reduce OCD symptoms and ultimately improve quality of life.
If you or someone you know has been living with OCD or OCD symptoms, and provided you meet the overall criteria, you could be reimbursed up to £490 for your time and participation in the clinical trial plus reasonable travel expenses.
If the treatment works, you may be able to receive nearly a year’s worth (48 weeks) of the medication free of charge as part of an open-label extension study.
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You can find out more and register your interest HERE.
As explained in the summary for this clinical trial, “people with OCD tend to have signalling pathways in the brain which are overactive, causing intrusive thoughts, compulsive behaviour or other OCD symptoms.
“Previous clinical trials suggest that the study medication works to dampen down these overactive pathways which may help people with OCD when used in combination with their usual antidepressant medication.”
The study is expected to run for approximately five months. The trial itself will involve taking the oral medication or a placebo daily for ten weeks alongside seven visits to the clinic for check-ups to examine if your OCD symptoms improve and how well you are coping with taking the medication.
As part of International OCD Awareness Week, MAC also looked intohow the condition affects people in the workplace and answered some of the public’s pressing questions surrounding the disorder with one of the organisation’s leading psychiatrists, Dr David Gregory.
To ensure optimal safety, each study participant must meet a pre-determined set of eligibility criteria. To be eligible for the trial, you need to:
Be aged between 18-65
Have had OCD symptoms or an OCD diagnosis for at least 1 year that affects daily life.
Be taking an antidepressant for your OCD that isn’t fully helping.
To ensure optimal patient safety, participants must not have any of the following:
Bipolar, schizophrenia, autism, Tourette’s, or other psychiatric conditions
Diagnosed with an eating disorder.
Have diabetes that requires insulin.
Other criteria will apply.
If you want to learn more about MAC Clinical Research or if you’re considering being part of the clinical trial, you can learn more and register your interest by visiting their OCD research webpage.
Featured Image — MAC Clinical Trial/The Manc Group
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Popular activewear brand Tala launches physical shop in Selfridges
Daisy Jackson
Tala, a popular British athleisure brand famed for its flattering range of womenswear, has officially launched in Selfridges.
The fashion label has opened a pop-up in the Trafford Centre today, showcasing a selection of its beautiful clothing and accessories.
The brand, founded by entrepreneur and influencer Grace Beverley, is famed for its stylish sports bras, comfortable leggings, and flattering dresses and tops.
Tala has built up a loyal following thanks to collections like DayFlex, Sculpt Seamless, Signature Sweats, and 365 Sculpting Lounge, much of which will be available to browse inside Selfridges.
It’s the first time Tala has ever had a physical retail presence, launching in all four Selfridges stores across the country (including Manchester’s two department stores at the Trafford Centre and Exchange Square).
The pop-up space at Selfridges Trafford Centre has been decorated with soft neutral colours, halo lighting, and plants.
Grace Beverley, who will greet shoppers at Selfridges Trafford Centre tomorrow at Tala’s launch event, said: “Anyone who knows Tala knows that we – and I – are completely product-obsessed, so for customers to be able to try on their favorite Tala pieces in person is incredibly exciting, and I couldn’t think of a better place to start than Selfridges, a retailer that holds so much history within its walls.”
Morgan Fowles, CEO of Tala, added: “We’re very excited to be launching Tala at Selfridges. It’s a milestone moment to experience our brand in a physical retail environment for the first time, to feel and experience the quality and unique attributes of our products that set our brand apart.”
And Bosse Myhr, buying director of menswear, womenswear, and childrenswear at Selfridges, said: “Selfridges has selected a beautiful edit of new and best-selling Tala products and will bring them to life in their exciting and unique retail environment.
The fountains outside Selfridges at the Trafford Centre, Manchester
“Known for curating the finest and most innovative brands whilst sharing our commitment to ESG, Selfridges provides the perfect backdrop to connect with a broader audience whilst strengthening our bonds with our community.
“We are thrilled to welcome activewear brand, TALA to Selfridges as their first physical retail partner globally. It’s really important at Selfridges to nurture and platform emerging brands, and so we are super excited to be working with talented entrepreneur and founder Grace Beverley.”
A curated selection of highlights from Tala’s range is now available to browse in person in Selfridges Trafford Centre and Selfridges Exchange Square – and you need to get your hands on these leggings to believe how soft they are.
Science and Industry Museum reveals ‘gloriously gross’ half term events lineup
Emily Sergeant
One of Manchester’s most-visited museums has unveiled its exciting events lineup ahead of half term in a couple of weeks time.
Fancy diving into the “gloriously gross” world of our brilliant bodies?
It’s certainly not an invite you get every day, but as schools across Greater Manchester break up for half term at the end of this month, and parents and carers gear up to entertain the little ones, the Science and Industry Museum has, thankfully, just announced a wide range of events and activities especially for the holidays.
Anyone who considers themselves to be “curious about the incredible inner workings of the human body” are invited to join in with the series of anatomy-themed special events, star-studded appearances, and half term transformations.
And the best bit is that a good chunk of the events planned are actually open for you to get involved with for completely free of charge.
As the curtains on Operation Ouch! are due to close for good on Sunday 9 June, the museum has chosen to dedicate the entire month of May to celebrating the record-breaking exhibition and making sure it goes out in “a blaze of glorious grossness” by having it inspire all the upcoming ‘brilliant bodies’ events – and this half term is no different.
The Science and Industry Museum has revealed its ‘gloriously gross’ half term events lineup / Credit: Science Museum Group
As well as exploring the exhibition before it closes, mini Mancs can also bring a bear (or any soft squishy friend) to the museum and take them round the departments of the ‘Teddy Hospital’, as well as learn all about looking after their brains, bones, and bottoms with fun and fascinating activities, and find out how their skeleton works, what their poo is made of, and why we have blood.
The museum‘s team of Explainers will also be back in action this half term.
They’ll be putting on interactive science shows packed with “fun facts and wow moments” that explore how and why our bodies are all the same, but different too.
There’s so much to discover and explore about our ‘brilliant bodies’ at the museum this month / Credit: Science Museum Group
Away from the ‘brilliant bodies’ events, if you haven’t had the chance the make the most of the museum’s smash-hit gaming exhibition, Power UP, then this upcoming half term is the ideal time to do so.
Revolution Manchester, the museum’s interactive Experiment gallery, and the Textiles Gallery are also open for exploring for free all throughout the half term week.
Both free entry tickets to the museum, and charged-for tickets for Operation Ouch! Food, Poo and You and Power UP, can be booked now on the Science and Industry Museum website.