Researchers are looking for participants to test a potential new treatment for OCD
Volunteers taking part will be reimbursed for their time (including reasonable travel costs) and may be offered the study medication free of charge for 48 weeks.
A leading clinical research organisation is running a clinical trial to test a potential new medication for people living with OCD.
According to the NHS, it is estimated that a quarter of a million people are living with OCD in the UK at some point in their lives, that’s equivalent to 12 in every 1,000.
This number increases drastically when we consider those who haven’t received a diagnosis who could be living with OCD symptoms and not receiving the professional support they may need or understand why they are experiencing intrusive thoughts.
Dr Alex Worthington, Clinical Research Physician at MAC Clinical Research, explains that “obsessive-compulsive disorder, commonly referred to as OCD, is a mental health condition with three main parts: obsessions, emotions, and compulsions.
For #OCDWeek, we wanted to highlight some statistics and information to raise awareness of #OCD.
If you have OCD and are having little to no response to your current antidepressant treatment, you may be eligible to take part in a clinical trial.
“Obsessions are persistent thoughts, images, doubts, worries, or urges that intrude on an individual’s mind, despite being unwanted.
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“These thoughts can cause significant mental discomfort or anxiety. Some of the emotions felt due to intrusive thoughts can include guilt, depression, and disgust.
“Compulsions refer to repetitive behaviours that an individual engages in to temporarily alleviate the anxiety caused by the obsession. Examples of compulsions include checking if a door is locked multiple times or repeating certain phrases mentally.”
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There’s a need for more effective treatment options for OCD, which is why award-winning clinical research organisation, MAC Clinical Research is conducting a clinical trial to test a potential new treatment that is hoped to reduce OCD symptoms and ultimately improve quality of life.
Here at MAC, our OCD clinical trial is open for people struggling with OCD symptoms.
Eligible participants will receive up to £490 plus reasonable travel expenses.
If you or someone you know has been living with OCD or OCD symptoms, and provided you meet the overall criteria, you could be reimbursed up to £490 for your time and participation in the clinical trial plus reasonable travel expenses.
If the treatment works, you may be able to receive nearly a year’s worth (48 weeks) of the medication free of charge as part of an open-label extension study.
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You can find out more and register your interest HERE.
As explained in the summary for this clinical trial, “people with OCD tend to have signalling pathways in the brain which are overactive, causing intrusive thoughts, compulsive behaviour or other OCD symptoms.
“Previous clinical trials suggest that the study medication works to dampen down these overactive pathways which may help people with OCD when used in combination with their usual antidepressant medication.”
The study is expected to run for approximately five months. The trial itself will involve taking the oral medication or a placebo daily for ten weeks alongside seven visits to the clinic for check-ups to examine if your OCD symptoms improve and how well you are coping with taking the medication.
As part of International OCD Awareness Week, MAC also looked intohow the condition affects people in the workplace and answered some of the public’s pressing questions surrounding the disorder with one of the organisation’s leading psychiatrists, Dr David Gregory.
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One of MAC’s leading psychiatrists sheds light on OCD treatment.
To ensure optimal safety, each study participant must meet a pre-determined set of eligibility criteria. To be eligible for the trial, you need to:
Be aged between 18-65
Have had OCD symptoms or an OCD diagnosis for at least 1 year that affects daily life.
Be taking an antidepressant for your OCD that isn’t fully helping.
To ensure optimal patient safety, participants must not have any of the following:
Bipolar, schizophrenia, autism, Tourette’s, or other psychiatric conditions
Diagnosed with an eating disorder.
Have diabetes that requires insulin.
Other criteria will apply.
If you want to learn more about MAC Clinical Research or if you’re considering being part of the clinical trial, you can learn more and register your interest by visiting their OCD research webpage.
For #OCDWeek, we wanted to share what some of our clinical trial participants said made them want to take part in OCD clinical research with MAC.
Featured Image — MAC Clinical Trial/The Manc Group
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Beloved Manchester Italian restaurant unveils big refurb
Thomas Melia
Much-loved Italian restaurant Italiana Fifty-Five has just unveiled a beautiful refurbishment at one of its Manchester sites, along with a new menu of fresh, handmade pasta.
Gone is the famous yellow colour palette of this Italian eatery as they swap in a sophisticated and regal turquoise blue at their Liverpool Road restaurant.
This establishment is known for its impressive shop-window pasta making stations where you can see your food prepared live in-store and while walking past outside the venue.
They’re continuing their foodie legacy serving carby creations, like a flaming cheese wheel pasta where staff blowtorch the cheese to ensure it’s as melty as possible.
One of the biggest menu highlights at Italiana Fifty-Five is the cappellacci, which comes in two equally gorgeous forms and much like its English translation, emulates tiny hats.
These cute little plates come in two delicious stuffed pairings – the burrata, combined with a tangy tomato and beef filling, and a salmon with cream sauce and fresh lemon for a match made in heaven.
Beloved Manchester Italian restaurant Italiana Fifty-Five unveils big refurb. Credit: The Manc GroupInside Italiana Fifty-Five as it unveils a new look on Liverpool Road. Credit: The Manc Group
How can you think of anything more ideal than a table full of hearty and home-comforting meals than one that also features an array of beautiful sides?
Usual delights like the burrata on a bed of rocket, tomato and finished off with a balsamic vinegar glaze area great addition to your already faultless food.
Cheesy garlic pizza bread is quintessential when dining in an Italian restaurant, and Italiana 55’s lovely flavour-packed favourite is a go-to when ordering here.
The Liverpool Road restaurant also has a tonnata pizza which uses toppings that are an exact ingredient breakdown of the Mediterranean sauce, which it shares its name with.
In photos: Italiana Fifty-Five has undergone a refurb. Credit: The Manc Group
What better way to wolf down some incredible Italian feasts than with some perfectly paired alcoholic offerings like the classic Aperol spritz, trusted espresso martinis and a selection of fine wines.
Their menu is staying as tasty as ever with their delicious pizzas and pastas, with the new fresh pasta menu available at their restaurants on Liverpool Road and in Didsbury.
Rochdale’s incredible fire festival will bring blazing sculptures and fiery displays to town this month
Daisy Jackson
Rochdale will be filled with dazzling pyrotechnic displays later this month when the Ignite Fire Festival returns to town.
The spectacular free event will see the gardens opposite the Rochdale Town Hall – which reopened to the public earlier this year – transformed with fiery displays, blazing sculptures and illuminated installations.
The smash hit event debuted last year, attracting more than 10,500 people, and this year’s will be even bigger with three nights of magical family entertainment.
And the festival will culminate on the Sunday with the Rochdale Christmas lights switch-on.
Ignite Fire Festival comes from Walk the Plank, the outdoor arts specialists behind some of the UK’s biggest and best outdoor arts events, who have called upon artists and pyro technicians to create the many installations on show.
Between 5pm and 8pm each night, visitors will be able to walk past fire-based sculptures like goblets of fire, a daisy chain of flaming flowers, a fire bird with blazing eyes, and smaller birds circling a flaming nest – to name just a few.
There’ll also be sculptures that twist, flap and erupt with balls of fire, and ‘In The Balance’ will be a festival highlight, where rotating globes of flame seemingly defy the laws of physics.
Ignite Fire Festival is back in Rochdale this month. Credit: Supplied
Each evening, a fire drawing designed and made by local residents will be ignited alongside flaming hot performances from some of the UK’s top talent including Flame Oz – a thrilling fire dancing and juggling show.
There’ll also be performances from Liverpool’s Bring the Fire Project, local favourites Skylight Circus Arts, and street theatre and interactive arts group Travelling Light Circus.
Visitors should look out for Drum Machine, a 20-strong drumming collective, The Fire Man Dave performing a live fire show with fire eating and juggling, and Astro Aliens, a trio of cosmic beings that will entertain all ages.
The incredible event, sponsored by car supermarket The Trade Centre UK, is set to take place between Friday 22 and Sunday 24 November.
Ignite Fire Festival takes place in the gardens opposite the Rochdale Town HallThere’ll be performers as well as pyrotechnic sculptures. Credit; SuppliedIgnite Fire Festival is back for a second year. Credit: Supplied
After exploring the gardens, you’ll be able to pick up hot food, mulled wine and other seasonal drinks served each night.
On Sunday, Father Christmas will be in town to switch on the Christmas lights at 5.30pm in front of the town hall.
Councillor Sue Smith, cabinet member for communities and co-operation at Rochdale Borough Council said: “Last year’s Ignite Fire Festival and Christmas Light’s Switch On was a fantastic event and an instant hit with audiences from across Greater Manchester.
“It’s an exciting and unique event and the perfect addition to our big switch-on, providing family entertainment across the weekend.”
Mark Bailey, founder and owner of sponsor Trade Centre UK added: “Our partnership with Ignite Fire Festival and the Rochdale Christmas Lights Switch On is a fantastic opportunity to give back to a community that has welcomed us so warmly.
“At Trade Centre UK, we believe in more than just selling cars; we believe in being part of the fabric of the local area. Supporting events like this, which bring people together to celebrate in the heart of Rochdale, aligns perfectly with our core values of community and connection.”
The event is free, and no tickets are required. Ignite is organised by Rochdale Borough Council in partnership with Walk the Plank and Culture Co-op, a ‘Creative People and Places’ programme, funded by Arts Council England.
Find out more and plan your visit to Ignite Fire Festival HERE.
Danny Jones -
16th November 2023 
