Researchers are looking for participants to test a potential new treatment for OCD
Volunteers taking part will be reimbursed for their time (including reasonable travel costs) and may be offered the study medication free of charge for 48 weeks.
A leading clinical research organisation is running a clinical trial to test a potential new medication for people living with OCD.
According to the NHS, it is estimated that a quarter of a million people are living with OCD in the UK at some point in their lives, that’s equivalent to 12 in every 1,000.
This number increases drastically when we consider those who haven’t received a diagnosis who could be living with OCD symptoms and not receiving the professional support they may need or understand why they are experiencing intrusive thoughts.
Dr Alex Worthington, Clinical Research Physician at MAC Clinical Research, explains that “obsessive-compulsive disorder, commonly referred to as OCD, is a mental health condition with three main parts: obsessions, emotions, and compulsions.
For #OCDWeek, we wanted to highlight some statistics and information to raise awareness of #OCD.
If you have OCD and are having little to no response to your current antidepressant treatment, you may be eligible to take part in a clinical trial.
“Obsessions are persistent thoughts, images, doubts, worries, or urges that intrude on an individual’s mind, despite being unwanted.
“These thoughts can cause significant mental discomfort or anxiety. Some of the emotions felt due to intrusive thoughts can include guilt, depression, and disgust.
“Compulsions refer to repetitive behaviours that an individual engages in to temporarily alleviate the anxiety caused by the obsession. Examples of compulsions include checking if a door is locked multiple times or repeating certain phrases mentally.”
There’s a need for more effective treatment options for OCD, which is why award-winning clinical research organisation, MAC Clinical Research is conducting a clinical trial to test a potential new treatment that is hoped to reduce OCD symptoms and ultimately improve quality of life.
Here at MAC, our OCD clinical trial is open for people struggling with OCD symptoms.
Eligible participants will receive up to £490 plus reasonable travel expenses.
If you or someone you know has been living with OCD or OCD symptoms, and provided you meet the overall criteria, you could be reimbursed up to £490 for your time and participation in the clinical trial plus reasonable travel expenses.
If the treatment works, you may be able to receive nearly a year’s worth (48 weeks) of the medication free of charge as part of an open-label extension study.
You can find out more and register your interest HERE.
As explained in the summary for this clinical trial, “people with OCD tend to have signalling pathways in the brain which are overactive, causing intrusive thoughts, compulsive behaviour or other OCD symptoms.
“Previous clinical trials suggest that the study medication works to dampen down these overactive pathways which may help people with OCD when used in combination with their usual antidepressant medication.”
The study is expected to run for approximately five months. The trial itself will involve taking the oral medication or a placebo daily for ten weeks alongside seven visits to the clinic for check-ups to examine if your OCD symptoms improve and how well you are coping with taking the medication.
As part of International OCD Awareness Week, MAC also looked intohow the condition affects people in the workplace and answered some of the public’s pressing questions surrounding the disorder with one of the organisation’s leading psychiatrists, Dr David Gregory.
One of MAC’s leading psychiatrists sheds light on OCD treatment.
To ensure optimal safety, each study participant must meet a pre-determined set of eligibility criteria. To be eligible for the trial, you need to:
Be aged between 18-65
Have had OCD symptoms or an OCD diagnosis for at least 1 year that affects daily life.
Be taking an antidepressant for your OCD that isn’t fully helping.
To ensure optimal patient safety, participants must not have any of the following:
Bipolar, schizophrenia, autism, Tourette’s, or other psychiatric conditions
Diagnosed with an eating disorder.
Have diabetes that requires insulin.
Other criteria will apply.
If you want to learn more about MAC Clinical Research or if you’re considering being part of the clinical trial, you can learn more and register your interest by visiting their OCD research webpage.
For #OCDWeek, we wanted to share what some of our clinical trial participants said made them want to take part in OCD clinical research with MAC.
Featured Image — MAC Clinical Trial/The Manc Group
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Scare City returns to abandoned North West theme park for another year of terror this Halloween
Emily Sergeant
Scare City will be back in the North West once again this Halloween with its spine-chilling immersive horror experience.
After having firmly cemented itself as the region‘s favourite horror event for the past five years running, Scare City has announced that it’s getting ready for ‘another year of terror’ over in Lancashire, and although it may be the middle of summer right now and spooky season is some time off, tickets are currently on sale.
One summer is over, the nights draw in, and the temperatures begin to drop, Scare City will be taking over the grounds of the abandoned Camelot Theme Park once again from this September, just as it has done for the past four years following the success of its initial 2020 launch as a drive-in cinema.
This year’s event is set to feature a selection of terrifying zones.
Scare City returns to an abandoned North West theme park for another year of terror this Halloween / Credit: Jason Roberts (Supplied)
The abandoned theme park will be transformed into a sprawling post-apocalyptic nightmare, featuring new immersive experiences.
Some of the new zones include desolate woodland ‘The Hollow’, and the ‘Puppet Master’, a toy maker’s workshop where innocent toys hide deep dark secrets, as well as the return of a number of familiar spooky spots like ‘The Slaughter House’ and ‘Carnivalley’.
The frightening Abyss is also set to return as ‘Abyss 2.0′, where thrill-seekers’ bravery will be put to the test in claustrophobic darkness, all while they’re unsure of what, or who, might be within reach.
Don’t worry though, if you need a bit of a break from all the terror, then once you’ve made it halfway around the attraction, you’ll arrive at the aptly-named the ‘Resurrection Zone’, so you can take a moment to fuel up on the feast of food and drink freshly-prepared by on-site vendors, all ready for the second half of the harrowing Halloween spectacular.
Scare City 2025 will take over Camelot Theme Park, in Charnock Richard near Chorley in Lancashire, from Thursday 25 September and run until mid-November.
Tickets are now available to book at £29.50 for standard entry, or £44.50 for the ‘Gold Entry’ (both plus a booking fee), which allows you to fast-track queues at the main entrance and at all zones, if you just can’t wait any longer to be scared.
Get your hands on tickets via the Scare City website here.
Featured Image – Supplied
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Manchester Arndale is hosting FREE workshops to help you ‘rework, restyle, and recycle’ your wardrobe
Emily Sergeant
Is your wardrobe feeling a little bland? Need to make some changes, but your bank account isn’t quite on the same wavelength? This event is here to help.
Those looking for some new ways to get creative with their style and put a spin on the clothes they already have are invited to head down to Manchester Arndale this weekend, as the Reimagine Your Fashion event is set to be a fun hands-on weekend celebrating personal style, smart choices, and sustainable ideas.
Whether you’re into upcycling, love yourself a styling session, or you just fancy doing something different in the city this summer, there’s something for everyone to get stuck into this weekend.
You can expect creative workshops, curated fashion rails, live styling tips, and a chance to give your pre-loved clothes a second life.
Oh, and did we mention it’s all free to take part in? Perfect.
There’s a collection of free ‘REWORK’ workshops taking place over the two-day event on Saturday 5 and Sunday 6 July, where you can learn how to turn old into gold – from patchwork denim makeovers, to scrunchie making, custom tote design, and loads more.
There’s no need to be a sewing pro either, as the workshops are beginner-friendly and designed to be relaxed and creative with all tools provided, so all you have to do is bring along the clothing items you want to upcycle.
Manchester Arndale is hosting free workshops to help you ‘rework, restyle, and recycle’ your wardrobe this weekend / Credit: Priscilla Du Preez | Ashley Diane Worsham (via Unsplash)
At the ‘RESTYLE’ sessions, Rosie, who is the stylist behind Manchester Arndale’s summer campaign, will break down this season’s biggest trends and show you how to style what’s in store now, as well as being on-hand for styling tips and outfit advice.
And finally, there’ll also be a ‘RECYCLE’ station and drop-off point where you pass on your clean pre-loved clothes to two brilliant local charities doing vital work right here in Manchester – MASH, which supports women involved in sex work and those facing homelessness or gender-based violence, and Mustard Tree which works to tackle poverty across Greater Manchester.
“Your clothes could be someone else’s fresh start,” a spokesperson for Manchester Arndale said ahead of the event.
Reimagine Your Fashion is taking place at Exchange Court in Manchester Arndale on Saturday 5 and Sunday 6 July running from 12pm, and you can find out more information and the times of the free workshops online here.
Danny Jones -
16th November 2023 
