Researchers are looking for participants to test a potential new treatment for OCD
Volunteers taking part will be reimbursed for their time (including reasonable travel costs) and may be offered the study medication free of charge for 48 weeks.
A leading clinical research organisation is running a clinical trial to test a potential new medication for people living with OCD.
According to the NHS, it is estimated that a quarter of a million people are living with OCD in the UK at some point in their lives, that’s equivalent to 12 in every 1,000.
This number increases drastically when we consider those who haven’t received a diagnosis who could be living with OCD symptoms and not receiving the professional support they may need or understand why they are experiencing intrusive thoughts.
Dr Alex Worthington, Clinical Research Physician at MAC Clinical Research, explains that “obsessive-compulsive disorder, commonly referred to as OCD, is a mental health condition with three main parts: obsessions, emotions, and compulsions.
For #OCDWeek, we wanted to highlight some statistics and information to raise awareness of #OCD.
If you have OCD and are having little to no response to your current antidepressant treatment, you may be eligible to take part in a clinical trial.
“Obsessions are persistent thoughts, images, doubts, worries, or urges that intrude on an individual’s mind, despite being unwanted.
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“These thoughts can cause significant mental discomfort or anxiety. Some of the emotions felt due to intrusive thoughts can include guilt, depression, and disgust.
“Compulsions refer to repetitive behaviours that an individual engages in to temporarily alleviate the anxiety caused by the obsession. Examples of compulsions include checking if a door is locked multiple times or repeating certain phrases mentally.”
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There’s a need for more effective treatment options for OCD, which is why award-winning clinical research organisation, MAC Clinical Research is conducting a clinical trial to test a potential new treatment that is hoped to reduce OCD symptoms and ultimately improve quality of life.
Here at MAC, our OCD clinical trial is open for people struggling with OCD symptoms.
Eligible participants will receive up to £490 plus reasonable travel expenses.
If you or someone you know has been living with OCD or OCD symptoms, and provided you meet the overall criteria, you could be reimbursed up to £490 for your time and participation in the clinical trial plus reasonable travel expenses.
If the treatment works, you may be able to receive nearly a year’s worth (48 weeks) of the medication free of charge as part of an open-label extension study.
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You can find out more and register your interest HERE.
As explained in the summary for this clinical trial, “people with OCD tend to have signalling pathways in the brain which are overactive, causing intrusive thoughts, compulsive behaviour or other OCD symptoms.
“Previous clinical trials suggest that the study medication works to dampen down these overactive pathways which may help people with OCD when used in combination with their usual antidepressant medication.”
The study is expected to run for approximately five months. The trial itself will involve taking the oral medication or a placebo daily for ten weeks alongside seven visits to the clinic for check-ups to examine if your OCD symptoms improve and how well you are coping with taking the medication.
As part of International OCD Awareness Week, MAC also looked intohow the condition affects people in the workplace and answered some of the public’s pressing questions surrounding the disorder with one of the organisation’s leading psychiatrists, Dr David Gregory.
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One of MAC’s leading psychiatrists sheds light on OCD treatment.
To ensure optimal safety, each study participant must meet a pre-determined set of eligibility criteria. To be eligible for the trial, you need to:
Be aged between 18-65
Have had OCD symptoms or an OCD diagnosis for at least 1 year that affects daily life.
Be taking an antidepressant for your OCD that isn’t fully helping.
To ensure optimal patient safety, participants must not have any of the following:
Bipolar, schizophrenia, autism, Tourette’s, or other psychiatric conditions
Diagnosed with an eating disorder.
Have diabetes that requires insulin.
Other criteria will apply.
If you want to learn more about MAC Clinical Research or if you’re considering being part of the clinical trial, you can learn more and register your interest by visiting their OCD research webpage.
For #OCDWeek, we wanted to share what some of our clinical trial participants said made them want to take part in OCD clinical research with MAC.
Featured Image — MAC Clinical Trial/The Manc Group
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Manchester City are hosting special Christmas-themed tours of the Etihad Stadium
Danny Jones
Manchester City FC’s critically acclaimed stadium tour is about to get super festive, as the Etihad Stadium are now hosting special Christmas-themed walks around the ground.
You’ve watched the tales of the ‘Centurions’, ‘Treble winners, the ‘Fourmidables’, and plenty of other ‘Cityzen’ stories play out in front of you, but have you visited the hallowed halls while their decked doughs of holly for yourself?
Well, now’s your chance.
Hosting a series of exclusive festive tours around the Etihad this month, Man City fans, club-obsessed kids, and football fanatic tourists in general can take a walk around the impressive sporting arena for the perfect early Christmas present.
In addition to being able to walk around the famous home of the Blues, sit in the home team dressing room and see the trophy cabinet, fans of all ages can now field questions with virtual Pep and Haaland in their very own press conference, before walking down the tunnel, into the dugout and sitting pitchside.
Once you’ve finished warming up the gaffer’s very own seat (they’re actually already heated), supporters can look forward to a brand-new dancing light display, plus more heartwarming entertainment in the form of Christmas carol audio recorded by Manchester’s very own Hallé Youth Choir.
As if that wasn’t enough, ‘Beyond the Blue Moon’ VR experiences and special ‘Etihad After Dark’ tours will be available, too, giving people from all over and of all ages an extra opportunity to turn up and make the most of this truly global club.
You can even grab a warming mulled wine or hot Vimto during the evening slots to keep your hands nice and toasty as you go around – be rude not to.
Rumour has it Santa may have left a gift lying around each day, too. Safe to say that puts our Advent calendar this year to shame…
Credit: Man City (supplied)
Here’s hoping he doesn’t get a telling off for wearing red…
Evening tours at the Eithad will be held from 5:30 and 6pm on 7, 12, 14, 18, 22 and December, and the main slot will be running all the way up until Christmas Eve (24 Dec).
You can even grab a warming mulled wine or hot Vimto to keep your hands nice and toasty as you go around – be rude not to.
Tickets start from only £26 per person and family passes are priced at just £60.
Better still, you can even spring for the VIP package if you fancy: a two-hour experience that is one of the most interactive and immersive you’ll find anywhere.
The Etihad Stadium is currently in the middle of a huge redevelopment, both in terms of size and things to do around the wider Campus, with the expanded North Stand not only seeing matchday fan capacity increased to over 60k, but a new club shop, sky bar, hotel, and a rooftop walk being added.
With that in mind, it’s no wonder that the already award-winning City stadium tours are simultaneously seeing an upgrade over the holiday period.
Being given the Tripadvisor seal of approval once again last year, as the club were once again recognised in the Travellers’ Choice ‘Best of the Best’ – putting them not just in the top three stadium tours in the UK but in the top 1% of the most highly rated in the world – things are only getting bigger.
You can find out full availability, timings and where to get tickets right HERE.
Manchester’s iconic Rylands building is being reborn – and the developers want to hear from you
Daisy Jackson
Manchester’s iconic Rylands building, formerly home to the Debenhams department store, is being reborn.
And now the developers working on its new chapter want Mancunians to weigh in on which businesses we want to see in the landmark building.
The transformation of Rylands Manchester will honour the heritage character of the building, which dates back to 1932, but will introduce contemporary design and a list of residents that’s bang up to date for our modern city centre.
The plans include building a four-storey extension with panoramic city views and a bright, central atrium. When it completes, this Grade II-listed art deco building will bring together workspace, retail, and leisure, right at the beating heart of town between the Northern Quarter, Piccadilly, Manchester Arndale, and the central business district.
Standing proudly at the top of Market Street, this next era for Rylands will establish it as an exciting new destination in the heart of town when its phased completion begins from late 2026.
Already confirmed to be moving in is Market Place Food Hall with its first northern location, which has signed on for a 15 year lease to occupy the ground floor of Rylands.
Market Place Food Hall is already confirmed to be moving into RylandsRylands is entering a new era
But now Rylands are putting it back to locals to ask what shops, restaurants, or cafes we’d love to see moving in.
It could be a high street hero you’ve loved for years, an independent business you’ve fallen for, or a foodie spot you return to time and time again.
Your ideas could help to shape the future of this landmark building and make it a destination us Mancs can be proud of.
And if you submit your suggestions in the comments of THIS Instagram post, you could be in with a chance of winning a £100 Love2Shop voucher (make sure you’re following @Rylands_manchester for a chance to win).
Danny Jones -
16th November 2023 
