Sandwich Technician
AJ Handley-Rowe -
10th November 2021
AJ Handley-Rowe -
10th November 2021 NHS rolls out new ‘life-extending’ ovarian cancer drug for first time in 20 years
Emily Sergeant
The NHS has approved a new ovarian cancer treatment for the first time in two decades.
From today, hundreds of women with ‘hard-to-treat’ ovarian cancer could benefit from a new life-extending drug on the NHS called mirvetuximab soravtansine, and it will be offered to patients living with whose disease has unfortunately stopped responding to standard chemotherapy treatments, providing them with new hope of extra time to live.
The rollout of the drug on the NHS follows a major global clinical trial involving eight NHS hospitals, which showed that the treatment delayed cancer progression and prolonged survival – with patients living 16.5 months on average compared to 12.8 months with chemotherapy.
One patient said the treatment enabled her to get on with life ‘rather than spending it in bed recovering from the side effects of chemotherapy’.
So, how does it work then?
ADVERTISEMENT
Well, the drug combines a ‘homing’ antibody with a cancer-killing medicine – often described by scientists as a ‘biological missile’ or ‘trojan horse’ therapy – and it works by attaching to ovarian cancer cells that have a protein called folate receptor alpha (FRα) on their surface, before releasing a cancer-killing molecule which destroys the cell from within.
The treatment is given intravenously, via a drip, over two to four hours, once every three weeks.
ADVERTISEMENT
The drug may also have ‘more tolerable’ side effects than traditional chemotherapy, with the treatment aimed more precisely at cancer cells than chemotherapy.
The NHS estimates up to 400 patients in England each year could benefit.
“This represents the most significant breakthrough in NHS treatment for these hard-to-treat ovarian cancers in over two decades, commented Professor Ruth Plummer, who is the NHS’s national clinical lead for cancer drugs.
Read more:
- Groundbreaking new ‘rapid’ jab to treat 14 different cancer types now available on NHS
- NHS to offer thousands of people access to ‘life-extending’ cancer drug
- Five-minute ‘super jab’ to treat 15 different types of cancer rolled-out on NHS
“We’re delighted it will now offer hundreds of women much-needed hope of precious extra time with their loved ones.
“It is part of a growing wave of more targeted cancer therapies which, by homing in on specific features of cancer cells, are helping us improve patients’ lives.”
Featured Image – Stephen Andrews (via Unsplash)
40-year-old Chinatown restaurant warns ‘we won’t last another decade’ in defiant statement
Daisy Jackson
There are some businesses that feel so much a part of the fabric of Manchester, it’s hard to imagine the city without them.
But a defiant statement from Happy Seasons, a decades-old family-run restaurant in Chinatown, has said that it’s ‘not sure how businesses like ours will survive in this new world’.
They wrote that is ‘feels like everything is stacked against small businesses’ and said ‘we won’t last another 5-10 years’.
Happy Seasons has been a cornerstone of Chinatown for more than 40 years, famed for its roast meats (proudly hung in the windows) and traditional Cantonese dishes.
Everyone who works in the restaurant has been in the trade for more than 20 years, they wrote, adding ‘it’s all they’ve ever known’.
Happy Seasons has said that their type of business – where everything is made fresh, from scratch, daily – is ‘slowly fading’.
They wrote: “Younger generations are slowly stepping away from hospitality. The government continues to increase costs on our industry, while bills, rent, and even basic stock keep rising. Sometimes it feels like everything is stacked against small businesses.”
The restaurant added: “We don’t think places like ours will last another decade if things continue the way they are.”
But in their defiant video shared to customers, the Chinese restaurant said: “We’re not going to let that stop us.
“We’re still going to put the hours in. We’re still going to make everything fresh. We’re still not going to cut corners.
“From our sauces and roasted meats to our soy sauce and sweet and sour sauce, so much of what we serve is made from scratch. The time, effort, and cost that go into these everyday dishes are much higher than they used to be.
“Even though it’s costing us more and more to operate, we’re going to do our best to stick around for as long as we can. Because there may come a day when traditional Chinese food, made the old fashioned way, becomes much harder to find here in the UK.
“So let’s make this one hell of a decade. Thank you for all the support over the years. It truly means the world to us.”
Read more
- A pizzeria where every pizza is served with scissors is opening at the Trafford Centre
- ‘Theatrical’ rotisserie chicken restaurant to open just off King Street
- The very best Chinatown restaurants in Manchester
Featured image: The Manc Group
More
Audio
Clint Boon takes us around Manchester's iconic Deaf Institute
Eats