The former Knott Bar is set to become a new Italian restaurant. The old owners have closed their doors for good and now the building has been taken under new management.
It’s always been an iconic venue in Manchester, sat on the edge of Deansgate and Castlefield, but now The Knott Bar is no more – at least, not as we’ve known it up to now.
Rather, the two-story hospitality venue is due for some big changes this autumn as news reaches us that it’s been acquired by a new operator and is set to become Manchester’s latest destination Italian restaurant.
Dom’s Paccheri al Ragu and Alle Verdure pizza / Image: Ellen Eats Out
Chef restauranteur Dominic La Cola has been a solid presence in the city for years, running his much loved Dom’s Tavola Calda from the other end of Deansgate.
For decades now, he’s been lovingly dishing up authentic pizza, pasta, and Southern Italian mains from his authentic little kitchen – but now the restaurant is on the move and it has found a new home inside the former Knott Bar.
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With Dom’s existing home landmarked for demolition, Dom’s Tavola Calda has now been pushed out by its landlord – and its owner now plans to reopen his popular Italian eatery at the other end of Deansgate, close to Castlefield Bowl.
Inside the old Dom’s Tavola Calda restaurant, which has now closed and will be moving into the former Knott Bar unit / Image: Dom’s Manchester
Speaking to The Manc, he revealed that he’s currently refurbishing the bar and plans to open his restaurant there sometime in the autumn.
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It’s good news for fans of his authentic kitchen, which has long been an Italian staple on Deansgate for those in the know.
When The Knott Bar reopens as Doms Italia later this year, it will serve up all his kitchen’s popular favourites with weekly specials appearing on the board alongside beloved antipasti dishes like the house fritto misto, homemade meatballs and signature oven-baked ribs.
Dom’s Tavola Calda has been a fixture on Deansgate for decades. The speciality pizza ‘Dom’s’ uses spicy sausage made in house, red onion, porcini and mozzarella / Image: Feast Street
In the meantime, whilst renovations take place all of the staff at Dom’s have moved over to the restaurant’s sister site Vincenzo Trattoria which is located just of St Ann’s Square.
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Sharing the news with their followers on social media, an update from the restaurant said:
“Good evening to all our customers friends and family of Doms,It comes with great regret that we have to close our doors for last time on Monday the 9th August.
Chef restauranteur Dominic La Colla pictured with his general manager and chef / Image: Dom’s Tavola Calda
“It has been an eventful and memorable 8 years, and we would like to thank all of you that have been to see us here at Doms, whether it was just for a coffee or an evening out.
“For the foreseeable future, all our staff will be moving over to our sister restaurant Vincenzo Trattoria, st Anne’s street manchester.
“Fortunately, it’s not the end of Doms as we will be opening a new restaurant at 374 deansgate Manchester in the up and coming months called Doms Italia , as soon as we have finished the renovation we will inform you all, again
“Thank you and hope to see you all soon in the near future.”
At a time when so many hospitality operators are struggling, it’s great to hear that such an iconic Manchester restaurant has found itself a new home and a new lease of life.
For more updates on the return of Dom’s, head over to the restaurant’s Instagram page here.
News
Government sets out multi-million-pound plan to move UK away from animal testing in science
Emily Sergeant
A £22m push to ramp up the UK’s move away from animal testing in science is set to bring together cutting-edge tech and research.
The latest figures show there were 2.54 million animal testing procedures in Great Britain in 2025, which is down 3.8% on 2024, but with a further update due to be released later this year, the Government is now moving to ‘capitalise’ on that momentum with funding to shift the nation onto alternative testing options.
A dedicated national research hub and nine new high-tech projects are planned to develop ‘better ways’ to test medicines on human biology rather than animals.
According to the Government, this means treatments for conditions like cancer and inflammatory bowel disease (IBD) could be developed ‘faster’ and ‘more precisely’ to not only help patients but crucially also move science away from traditional animal testing.
At the heart of the plans is a new Pre-clinical Translational Models Hub – based in Cambridge and backed by £20 million in Government funding, which will work to build and share models of human tissue, grown from NHS patients, to test new treatments.
The new hub will accelerate the development of testing on ‘organoids’ – tiny, simplified versions of a human gut, tumour or brain, using cells donated by patients.
From beating heart cells in a dish to AI that can predict how drugs move through the body, exciting alternatives to animal testing are transforming medical research.
We're investing £22m to help scientists develop the next generation of life-saving treatments. pic.twitter.com/1EWRQvwySa
— Dept. for Business, Innovation, Science and Trade (@biztradegovuk) August 12, 2026
Because these ‘organoids’ retain crucial features of a patient’s own biology, they will help researchers learn how a real person may respond to a drug and provide additional insights that can complement information that is currently obtained from animals.
Scientists will then be able to use these cutting-edge techniques in their own labs to work out which medicines are worth pursuing.
Overall, it’s hoped that the move will slash the time it takes to get ‘potentially life-changing’ treatments to market.
Alongside the funding for the new Hub, nine cutting-edge projects aimed at identifying new methods of animal-free scientific testing – from beating heart cells in a dish, to lab-grown human ear models, and AI that predicts how medicines move through the body – are being funded.
Sadly, many of these still rely on testing on dogs and monkeys, as it stands.
“This marks another significant step forward in the UK’s move away from animal testing in science and research,” commented Science Minister Chris McDonald.
“This is all about backing our world-leading researchers and innovators to improve lives, giving them the tools they need to deliver more effective treatments for horrendous diseases like cancer, while also preventing the need for animal testing wherever possible.
“It’s also a boost for our life sciences sector, fuelling opportunities for new investment and new jobs, and ensuring Britain is better off.”
Elbow get behind campaign to save Jodrell Bank from closure
Danny Jones
Manc band Elbow are among the latest to get behind the campaign to save Jodrell Bank Observatory from closing permanently.
The Greater Manchester natives famously played a sold-out gig at the important scientific and cultural landmark for a very special live album recording well over a decade ago, and know all too well the site’s national and, indeed, global heritage.
Choosing the Observatory and the rare chance to perform a show in the shadow of the world-renowned James Lovell Telescope, it probably remains one of their most significant standalone UK date ever.
With that in mind, the local lads have been left just as worried by the news of its impending closure as everyone else, and have therefore issued a fresh appeal to help keep it open.
Posting a timely statement on social media, the group wrote: “Jodrell Bank has long been close to elbow’s heart. In 2012, the band played beneath the Lovell Telescope for one of the most memorable shows in our history.
“The recent news that funding for the e-MERLIN radio telescope network is set to end in 2028 puts the future of the scientific work at Jodrell Bank under serious threat. It is a remarkable place, with an extraordinary history, and one that continues to play an important role in science, culture and education.”
In addition to reliving clips and images from the historic live set all the years later, they also pointed people towards their ‘elbow – Live at Jodrell Bank‘ album documentary, which has now been made available online for the very first time as part of wider efforts to raise awareness around the cause.
Directing people to key online resources shared by the institution and astrophysics centre itself following their unfortunate update late last month, the push to not only find the funding but sustain support for the facility continues to ramp up throughout the world of science, arts and industry.
For anyone who somehow missed the news – 2028 being the current deadline handed down as per budget cuts across the sector – concerned parties here in the North West and all over the country have since started petitioning to save Jodrell Bank Observatory from shutting down for good.
In addition to being described as a “huge blow” to the field by the Royal Astronomical Society (RAS), some have even gone so far as to describe the decision as a form of “vandalism” when it comes to research and British culture as a whole.
Having also served as the host venue for the annual bluedot Festival since 2016, the multi-genre science and arts celebration could soon be forced to find a new home.
The battle is far from over yet, and the community has time to rescue Jodrell Bank Observatory from its fate, but it will take lots of money and more notable public figures to make it happen.
Once again, you can do your bit by signing the petition mentioned above right HERE.
Georgina Pellant -
26th August 2021 
