A new report by experts from the British Medical Journal (BMJ) has revealed that there has been “a visible mark of the increasing incidence of nitrous oxide (N2O) misuse” since lockdown began.
Nitrous oxide – also known as laughing gas, “hippie crack”, balloons and nos – is the second most popular drug amongst young people in the UK.
Its popularity is believed to be due to the fact that it is cheap and easy to get hold of.
As defined by FRANK, nitrous oxide is “a colourless gas most commonly found in pressurised metal canisters [which] you may have seen lying around in streets outside bars and nightclubs”.
It is often consumed by “transferring the gas into a container (usually a balloon), then inhaling from the balloon” and this is because “inhaling nitrous oxide directly from the canister is very dangerous [as] the gas is under such high pressure, which can cause a spasm of the throat muscle and stop a person breathing.”
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Nitrous oxide slows down brain and body responses and the effects of the drug is known to vary depending on how much has been inhaled.
Negative side effects of the inhalation of nitrous oxide include severe headaches, dizziness, inability to think straight and short-lived, but intense feelings of paranoia. Regular use can stop you forming white blood cells properly and heavy regular use can result in deficiency of vitamin B12. Severe B12 deficiency can lead to serious nerve damage, causing tingling and numbness in the fingers and toes – this can be very painful and make walking difficult.
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More serious side effects range from the risk of falling unconscious and/or suffocating from the lack of oxygen, which can/has lead to death.
The supply of nitrous oxide as a recreational drug is illegal under the UK’s Psychoactive Substances Act 2016, however, this does not appear to have acted as a deterrent in illicit drug use.
A tweet by Twitter user @sixkenza, calling for ‘cancelling’ balloons, has recently brought nitrous oxide inhalation into mainstream conversation once again. The tweet contained a screenshot of a personal account by a sufferer of severe side effects from nitrous oxide inhalation, which left her hospitalised.
The chilling statement featured in the tweet read: “Balloons.”
“We all do them, use them and abuse them, but never think about the long term effects. I have lost all feeling in both [legs], I have collapsed in public multiple times and that’s why I came to hospital.”
“My legs had been feeling numb for a couple weeks now, but I expected it to go away. I have no balance, no brain and leg coordination and no reflexes in my legs whatsoever. I have a long road to recovery and the recovery isn’t even 100%. I have to have injections daily and for the rest of my life. MRI scans and physio to learn how to walk again.”
“This isn’t a joke”.
“I will never touch a balloon again and I hope this is a wake up all to all of you. Your effects won’t be immediate, they will creep up on you slowly, so please stop doing them because they can leave you paralysed for life.”
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The tweet subsequently went viral since posting, going on to amass well over 8,000 retweets, 17,000 likes and hundreds of responses from people expressing shock and their own messages of warning, as well as sharing accounts of similar experiences and stories.
people forget that nitrous oxide is literally used when women give BIRTH and even that is mixed with 50% oxygen, whyyy would you inhale that voluntarily pls,
Balloons are literally the reason I have fits and lose my memory a lot, literally all year last year I was having MRI scans and currently waiting for an appointment to go Sheffield hospital for radiotherapy, from jan 2019 I was havin seizures between 6-12 times a week, stupidity https://t.co/d7jMfusozC
Honestly this should be a wake up call for a lot of you! No one thinks about the seriousness of it until something bad happens to them. I have and always will be against them however pathetic it may sound ??♀️ https://t.co/7c2zmNVKeK
we need to stop thinking we’re bulletproof ? i thought i was until i experienced the scariest 20 seconds of my life which felt like 20 minutes. couldn’t speak, hear or see anything followed my severe panic attacks and difficulty breathing for hours. they are SO dangerous !! https://t.co/verxTJHOVx
Rather worryingly, a few of the tweet responses also seemed to indicate a confusion on the correlation between balloons and nitrous oxide.
Some tweets revealed that people were unaware it was nitrous oxide contained within balloons and others even appeared to be under the assumption the substance filling the balloons that are referred to in the statement in question was actually helium.
This just highlights how much uncertainty there is and potentially offers explanation as to why such tragic situations may occur.
Whilst it’s wrong to claim that the negative side effects of nitrous oxide inhalation are not widely known, regularly discussed or previously warned against, we can only hope that the attention this tweet has and continues to receive, will go some way to serving as a wake up call for a newer generation of individuals who are seemingly appearing to abuse this drug more than ever before.
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More information on the effects of nitrous oxide can be found via FRANK here.
To read the full report by the British Medical Journal (BMJ) into the rise of N2O consumption during lockdown, you can do so here.
News
Greater Manchester restaurants are adding an extra £1 to bills to help fight homelessness this Christmas
Emily Sergeant
Dozens of local restaurants will be adding an extra £1 onto every bill over the festive season to help fight street homelessness.
People in Greater Manchester are once again able to give back while they dine at some of the best restaurants the region has to offer in the run up to Christmas, as the successful StreetSmart fundraising initiative is back for another year.
This year, 26 fantastic restaurants have come together to support local homeless charities as the campaign launched this past Saturday (1 November).
Manchester independents such as Mana, Erst, Climat, 10 Tib Lane, Ezra & Gill, Tartuffe, and Blue Eyed Panda are among those taking part in the campaign this year, alongside several city centre chain restaurants such as Lina Stores, Tampopo, Banyan, Manahatta, and San Carlo.
StreetSmart works by each participating restaurant adding an extra £1 to every bill they deliver throughout November and December, with all of the money raised going directly to local homeless organisations, thanks to StreetSmart’s official sponsorship from LandAid.
The funds raised by StreetSmart in Greater Manchester this year will support the crucial work of organisations such as CentrePoint, which funds Independent Living Advisors for young people, and Real Change Manchester, which plugs into the existing homelessness charities to provide that extra boost of funding that makes all the difference.
The StreetSmart team says it’s determined to deliver another record-breaking year in 2025, and provide much-needed support to the services that help some of the most vulnerable people in the city.
Manchester restaurants are adding an extra £1 to bills to help fight homelessness this Christmas / Credit: Supplied | Rifqi Ali Ridho (via Unsplash)
“The festive period can be an incredibly tough time for the vulnerable people in our community,” explained Glenn Pougnet, who is the Director of StreetSmart.
“StreetSmart provides a simple way for people to help some of our city’s most in need. Giving back whilst dining out at Christmas is what StreetSmart is all about, and we’re thrilled to have so many restaurants already taking part.
“Every £1 added to a bill adds up and makes a huge difference.”
Featured Image – John Carey (Supplied)
News
Police appeal for information after pedestrian killed on Mancunian Way followed earlier welfare concern reports
Emily Sergeant
Police are continuing to appeal for information after a pedestrian was killed on Mancunian Way during the early hours.
Greater Manchester Police (GMP) explained that the shocking incident occurred at approximately 12:50am on Friday 31 October when it was reported that a Volkswagen Passat had collided with a man in his 20s.
Sadly, the collision was fatal and the pedestrian died at the scene.
The driver of the Volkswagen, a man in his 40s, was subsequently arrested on suspicion of causing death by dangerous driving.
Following the incident, subsequent police enquiries have established that a call was made to the force shortly after midnight which reported concern for a man walking on the carriageway, and GMP says it believes the man in that report was the man who was involved in the fatal collision.
Officers were sent out as ‘high priority’ to carry out an extensive search of the surrounding area after the report was made, but it was said that they couldn’t locate him.
#UPDATE | Officers are continuing to appeal for information following the fatal collision on Mancunian Way this morning.
We have referred ourselves to the IPOC after reports that the victim was possibly spotted on the carriageway earlier that morning.
— Manchester City Centre Police (GMP) (@GMPCityCentre) October 31, 2025
Due to this earlier report, GMP has confirmed that it has referred itself to the Independent Office for Police Conduct (IOPC) to look into its response to the search.
The victim’s family is aware, have been updated, and they are being supported by specialist officers at this time.
GMP’s Serious Collision Investigation Unit is still appealing for anyone who may have witnessed the incident to come forward, and are particularly keen to speak to anyone who may have CCTV footage, dashcam, or mobile phone footage from the area in the moments leading up to the incident.
“This is a tragic incident for all involved and we express our deepest condolences to the family of the man who has lost his life, and whom we are doing our utmost to support at this time,” commented Sergeant Andrew Page.
Anyone with any information is asked to contact police on 0161 856 4741, quoting log number 111 of the 31/10/25, or by using the ‘report tool’ or LiveChat function on the GMP website – www.gmp.police.uk
Alternatively, you can contact Crimestoppers anonymously on 0800 555 111.