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Manchester woman now cancer free after groundbreaking UK-first transplant

Such an incredible story.

Emily Sergeant Emily Sergeant - 7th January 2025

A young woman from Manchester who was told she only had a short time to live is now cancer free after a UK-first transplant.

Bianca Perea, a 32-year-old trainee lawyer who lives in Wigan, was diagnosed with stage 4 bowel cancer – which is the most advanced kind – back in November 2021 when she was just 29, after only feeling a bit constipated and bloated, but otherwise having no other major symptoms.

After she was referred to her local hospital to have emergency bloods and a stool sample taken, followed by a colonoscopy and a biopsy, these investigations sadly revealed that she had bowel cancer, which had spread to all eight segments of her liver.

According to Cancer Research, only one in 10 people with advanced bowel cancer will survive for five years or more after their diagnosis.

But after becoming a patient at The Christie NHS Foundation Trust, a specialist cancer centre in Manchester, Bianca is now miraculously cancer free thanks to becoming the first person in the UK to have a liver transplant for advanced bowel cancer, along with other previous treatments included targeted therapy, chemotherapy, and surgery.

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Bianca was referred to The Christie’s local treatment centre in Wigan in early December 2021 where she had 37 rounds of a targeted drug called panitumumab, and chemotherapy over two and a half years.

According to The Christie, she had an “excellent response” to the treatment, with the tumour shrinking enough so that she could have an operation to remove the part of the bowel where it was.

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A Manchester woman is now cancer free after a groundbreaking UK-first transplant / Credit: The Christie NHS

However scans showed she still had tumours in her liver which couldn’t be operated on, and so she was then referred to Leeds Teaching Hospitals NHS Trust as she was found to be a suitable candidate for a transplant.

Before being added to the transplant list, Bianca had to be doing well on treatment for two years, and she hit this milestone in December 2023.

She was subsequently added to the list in February 2024, and had her operation this past summer.

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Despite all the odds, the surgery was successful, meaning she is now cancer free and the teams at Leeds and The Christie are “hopeful” that the cancer won’t return too.

“Within four weeks of going under the knife, I was able to drive and walk the family dogs, it was really quite incredible,” Bianca said.

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“To go from being told I’d only have a short time to live to now being cancer free is the greatest gift. I’ve been given a second chance at life and I’m going to grab it with both hands. I am so grateful to the family who agreed to donate their loved one’s liver.”

Featured Image – The Christie NHS