The NHS is launching the world’s biggest trial of a potentially life-saving blood test that can detect more than 50 types of cancer.
The Galleri test – which is already available in the US – can detect cancers that are not routinely screened for, and it can find where the disease is coming from in the body with a high degree of accuracy.
It looks for chemical changes in fragments of genetic code that leak from tumours into the blood – something done by some cancers long before symptoms even appear.
Around 140,000 volunteers in eight areas of England will be recruited to try the Galleri test.
The eight areas involved in the trial will be right here in Greater Manchester, as well as Cheshire and Merseyside, the North East, West Midlands, East Midlands, East of England, Kent and Medway, and southeast London.
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The NHS trial – which is being led by the Cancer Research UK and King’s College London Cancer Prevention Trials Unit, together with Grail that developed the Galleri test – will invite people from different backgrounds and ethnicities who are aged between 50 and 77 to take part, providing they have had a cancer diagnosis in the last three years.
Blood samples will be taken at mobile testing clinics across the eight areas over the coming weeks, in 12 months’ time, and again in two years.
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The first results are expected by 2023 and, if successful, the test could be in use from 2024.
Today the NHS launches the world’s largest trial of a revolutionary blood test which detects over 50 types of cancer before symptoms appear.
The test is said to have been especially effective at finding cancers that are more difficult to identify early, such as head and neck, bowel, lung, pancreatic, and throat cancers – but it cannot detect all cancers.
For this reason, it would not replace NHS screening programmes such as those for breast, cervical, and bowel cancer.
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The NHS said the test could play a major part in the health service’s ambition to catch 75% of cancers at an early stage, which is when they are easier to treat.
Speaking as the test trial launches, Amanda Pritchard – Chief Executive at the NHS – said: “This quick and simple blood test could mark the beginning of a revolution in cancer detection and treatment here and around the world.
“By finding cancer before signs and symptoms even appear, we have the best chance of treating it and we can give people the best possible chance of survival.”
Around 140,000 volunteers in eight areas of England will be recruited to try the Galleri test / Credit: WallpaperFlare
Professor Peter Sasieni – director of the unit and one of the trial’s lead investigators – added: “The test could be a game-changer for early cancer detection and we are excited to be leading this important research.
“Cancer screening can find cancers earlier when they are more likely to be treated successfully, but not all types of screening work.”
Featured Image – Pxfuel
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Salford City FC reveal new club crest ahead of return to orange kit
Danny Jones
Salford City FC have finally revealed their new club crest, paying homage to both their historic and present badge, as they prepare to wear predominantly orange kits once again.
The Greater Manchester club are enjoying a healthy injection not only of investment but ideas and, indeed, a decent bit of form in turn.
Currently sitting sixth in the League Two standings and looking more than capable of scrapping with other third division hopefuls around them in the table, the end of this season could be the start of a fresh chapter for the Salford sporting institution.
Regardless of whether they go up following the conclusion of this campaign or not, the newly restructured ownership group is certainly looking to make this the start of a new era.
Officially debuting the new Salford City badge in the teaser video shared above on Tuesday, 23 December, you could call it an early Christmas gift for Ammies supporters.
Writing on social media, the club said: “Our heritage. Our culture. Inspiring our future. From next season, Salford City FC will adopt a bold new identity, playing in orange with a new Club crest.
“Following recent consultations, 72% of fans voted to adopt this new Club crest from the start of the 2026-27 season.”
A lengthier statement continues: “The new Crest comes after extensive consultation with fans over the past several months.
“It was designed in conjunction with renowned NYC-based agency MILK, and in recent weeks, fans have heard from co-owners Gary Neville and Sir David Beckham about the potential opportunities the new crest can offer the Club – from building our fan base globally to exciting new merchandise products.
This latest unveiling comes after confirmation of the club reverting to an orange-led colour scheme and home shirt.
In addition to hinting at plans to once again upgrade the Peninsula Stadium, the official club statement also digs into the inspiration behind the various features included in the latest redesign.
They are as follows:
A rampant Lion that has featured on crests of the past, breaking out of the badge, refusing to be contained. It captures the fierce, on-field attitude expected from a Salford team. Relentless in the pursuit of success, never held back.
A new Salford rose, inspired by the iconic Salford Lads Club, symbolises enthusiasm, desire, passion and admiration.
Concentric circles represent a bird’s eye view of the Salford Gasworks.
A typeface crafted from the custom lettering found in Salford’s streets.
You see a more detailed breakdown of the thought process behind the various features down below; it does make for an interesting little read.
Credit: Salford City (via club website)
Salford famously switched to red when Manchester United’s ‘Class of 92’ legends bought the club in partnership with businessman Peter Lim well over a decade ago.
Despite the initial takeover seeing the struggling side find their way back into the EFL following multiple promotions, The Ammies have lost momentum in recent years, and many die-hard matchgoers still take issue with the colour change (the notion being that they were reborn in the shadow of Man United).
Fast forward to now, and they reiterated that the plans – which follow the aforementioned official consultation held earlier this year – will see new insignia installed in time for next season, not only on the latest batch of kits but around their soon-to-be further renovated home ground.
With Salford‘s rugby league community also set for its next iteration as of the 2026 season, it’s all change in Greater Manchester’s second city.
The 10 restaurant and bar closures that shocked Greater Manchester in 2025
Daisy Jackson
Greater Manchester has one of the most exciting and fastest-growing restaurant scenes on the planet – but that doesn’t make our city immune from hospitality closures, as 2025 has shown.
Given the economic climate and the increasing pressures on hospitality, it’s actually shocking (and a relief) that we haven’t lost even more beloved local spots.
In 2025, there have been some high-profile closures in Manchester that no one saw coming, as we bid a sad farewell to some local legends.
The good news is that the number of openings still outstrips the number of closures – you can see some of the biggest spots we welcomed last year HERE.
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Almost Famous
Greater Manchester
Almost Famous / Credit: The Manc Group
It’s no surprise that this was one of the biggest stories in Manchester in 2025, because we simply could not believe our eyes when Almost Famous announced its closure.
The burger craze of the mid-2010s may have died down, but this spot had always felt like a Northern Quarter OG with a loyal enough following to stand the test of time.
Alas, it closed its doors very suddenly back in January, shortly followed by its sister smash burger brand Super Awesome Deluxe, with a staggering outcry and a lot of fall-out locally.
Thankfully, a short while later it was rescued by the team behind PINS Social Club.
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Hip Hop Chip Shop
Ancoats
Hip Hop Chip Shop / Credit: The Manc Group
Another sad day for the Manchester food scene arrived in February, when Ancoats favourite The Hip Hop Chip Shop announced its closure.
Having first opened in 2014 as a street food stall, to opening their own site in Ancoats, the present financial pressures took their toll, and Hip Hop Chip Shop shut its shutters just a few weeks later.
We still fantasise about their battered halloumi.
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Another Heart To Feed
Northern Quarter
Another Heart to Feed / Credit: The Manc Group
It felt like one of the Northern Quarter’s top brunch spots, and with queues around the block nearly all the time, seemed like a safe spot.
But the award-winning Another Heart to Feed’s popularity was not enough to overcome the challenges facing the industry.
In their statement, this lovely brunch spot and wine bar thanked customers and staff, past and present – you can read more here.
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Mother Mary’s
Oxford Road
Mother Mary’s / Credit: The Manc Group
One of Manchester’s newest Irish bars announced its sudden and immediate closure in November, citing financial pressures.
Mother Mary’s took over the old student haunt that was Font bar, just off Oxford Road, filling the venue with a state-of-the-art sound system for hosting live music and club nights.
It was much more than just an Irish bar and had become a safe space for so many locals – accessible, queer-inclusive, independent, and dedicated to championing local talent.
One of Manchester’s most legendary bars closed its doors after 13 beautiful years in the city earlier this year, shocking us and everyone who loved it.
Sandinista quietly shut down in October, throwing one final knees-up for loyal (and very sad) punters.
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The bar, just off St Ann’s Square, was famed for its menu of beers, tequila, and cocktails, including a pint of Zombie served on fire.
There’ll never be another one like it.
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Bohemian Arts Club
Stockport
Bohemian Arts Club / Credit: The Manc Group
Stockport lost a good one back in September – Bohemian Arts Club, the stunning cocktail bar launched by Blossoms frontman Tom Ogden and his wife Katie, closed for good.
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It had been a much-loved addition to town, a real vintage-style speakeasy serving top quality drinks, and you could feel all the love the couple had poured into it (even down to the heart-shaped chairs handmade by Katie’s mum and dad).
Thankfully, it stayed in the family – Katie’s incredibly successful Bohemian Salon has expanded from downstairs to take over the entire three-storey building.
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Feel Good Club
Northern Quarter
Feel Good Club / Credit: Supplied
After five incredible years in the city, brewing up some of the finest coffee, serving an all-day brunch menu full of all your favourite comfort food dishes, hosting countless events, and just generally being a wholesome community space for anyone and everyone who needs it, it’s the end of the road for Feel Good Club.
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Founders Kiera and Aimie sadly announced they would be closing the doors to their Northern Quarter cafe in the summer, after struggling to stay afloat this past year like so many other local indies.
They said: “We’ve had the time of our lives, and met the most incredible people along the way.”
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Kala
Manchester City Centre
It was part of Gary Usher’s acclaimed group of restaurants, but Elite Bistros shut down one of its top spots earlier this year.
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City centre bistro Kala closed for good back in June, with a heartfelt and very honest statement.
Usher wrote: “Thank you to all the team past & present & I’m so sorry to all of you and all the guests that I couldn’t create something with longevity.”
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Medlock Canteen
New Jackson
Medlock Canteen / Credit: The Manc Group
Just months after celebrating its first birthday, Medlock Canteen announced it was moving out of the Deansgate Square neighbourhood.
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The brilliant local restaurant served a really gorgeous menu that included rotisserie chicken, full English breakfasts, and quite possibly Manchester’s best Caesar salad.
It was all proper hearty food that you actually want to eat, with a stunning mid-century restaurant space and great drinks too.
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Osma
Prestwich
Osma / Credit: The Manc Group | Osma
Prestwich’s burgeoning restaurant scene was dealt a major blow at the start of 2025, when Osma announced its closure.
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The Scandi-esque restaurant was a front-runner of Prestwich’s ever-growing food and drink scene since it opened in 2020, fronted by Manchester born Danielle Heron, who you might recognise from the Great British Menu and MasterChef: The Professionals 2024, alongside Sofie Stoermann-Naess.
You can still find their brilliant cooking at Exhibition in the city centre, but as for the restaurant itself, Osma said they ‘struggled to find experience staff, leaving us with little to no personal life’.
The Manc -
13th September 2021 
