The NHS is launching the world’s biggest trial of a potentially life-saving blood test that can detect more than 50 types of cancer.
The Galleri test – which is already available in the US – can detect cancers that are not routinely screened for, and it can find where the disease is coming from in the body with a high degree of accuracy.
It looks for chemical changes in fragments of genetic code that leak from tumours into the blood – something done by some cancers long before symptoms even appear.
Around 140,000 volunteers in eight areas of England will be recruited to try the Galleri test.
The eight areas involved in the trial will be right here in Greater Manchester, as well as Cheshire and Merseyside, the North East, West Midlands, East Midlands, East of England, Kent and Medway, and southeast London.
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The NHS trial – which is being led by the Cancer Research UK and King’s College London Cancer Prevention Trials Unit, together with Grail that developed the Galleri test – will invite people from different backgrounds and ethnicities who are aged between 50 and 77 to take part, providing they have had a cancer diagnosis in the last three years.
Blood samples will be taken at mobile testing clinics across the eight areas over the coming weeks, in 12 months’ time, and again in two years.
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The first results are expected by 2023 and, if successful, the test could be in use from 2024.
The test is said to have been especially effective at finding cancers that are more difficult to identify early, such as head and neck, bowel, lung, pancreatic, and throat cancers – but it cannot detect all cancers.
For this reason, it would not replace NHS screening programmes such as those for breast, cervical, and bowel cancer.
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The NHS said the test could play a major part in the health service’s ambition to catch 75% of cancers at an early stage, which is when they are easier to treat.
Speaking as the test trial launches, Amanda Pritchard – Chief Executive at the NHS – said: “This quick and simple blood test could mark the beginning of a revolution in cancer detection and treatment here and around the world.
“By finding cancer before signs and symptoms even appear, we have the best chance of treating it and we can give people the best possible chance of survival.”
Professor Peter Sasieni – director of the unit and one of the trial’s lead investigators – added: “The test could be a game-changer for early cancer detection and we are excited to be leading this important research.
“Cancer screening can find cancers earlier when they are more likely to be treated successfully, but not all types of screening work.”
Featured Image – Pxfuel
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‘Danger to life’ amber wind warning issued for Greater Manchester as Storm Éowyn arrives
Emily Sergeant
Storm Éowyn is expected to bring very strong winds and widespread disruption to Greater Manchester later this week.
In case you hadn’t heard, the Met Office named Storm Éowyn yesterday, and confirmed that it will begin to influence the UK’s weather from early on Friday – with strengthening winds initially expected in the south west first, accompanying heavy rainfall, before it quickly spreads to the north and the rest of the UK as the morning progresses.
An amber warning for wind has been issued for large parts of the UK, including the majority of Greater Manchester, for most of the day on Friday.
#StormÉowyn has been named and is forecast to bring strong winds to much of the UK on Friday and into Saturday.
Coming into effect from 6am this Friday (24 January), the weather warning his means that power cuts are likely to occur, transport services will be affected with delays and cancellations, and there is a chance that buildings could be damaged.
Worse than that though, there’s even a ‘danger to life’ too, with potential injuries occurring from flying debris.
Speaking ahead of Storm Éowyn’s arrival in a couple of days time, Mike Silverstone, who is the Deputy Chief Meteorologist at the Met Office, said: “Storm Éowyn will bring a period of very unsettled, potentially disruptive, weather to the UK through Friday and into Saturday.
Warnings for strong winds, heavy rain and snow are in place across many parts of the UK during Thursday, Friday and into the weekend ⚠️
“The strongest gusts are likely to be felt across parts of Northern Ireland, northern England, northwestern Wales and western Scotland, where exposed sites could get gusts in excess of 80mph, which has the potential to cause impacts for those in these areas.
“There will also be some heavy rain, bringing some unpleasant conditions to end the week.”
The initial warning for Storm Éowyn has been issued several days in advance, so it’s important to stay up to date with the forecast on the Met Office website here in the coming days.
Featured Image – Wikimedia Commons
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The 2025/26 Premiership Women’s Rugby season has been delayed
Danny Jones
The next Premiership Women’s Rugby (PWR) season has been officially delayed by nearly three weeks.
Announced on Tuesday, 21 January, the decision has been taken in an effort to help promote the Women’s Rugby World Cup (WRWC), the proximity of which is rather close to the national union championship competition.
With sporting bodies also trying to nurture a growing interest in female rugby, the start of the next PWR season will be pushed back not only to give players more time to rest but in an effort to drive a larger audience to the WRWC as well, the final of which is being played here in England.
The hope is that it will also better the Red Roses’ chances of winning the international tournament in turn – fingers firmly crossed.
Get excited 🤩
The PWR 2025-26 Season will officially kick off on Saturday 25th October PLUS the PWR Cup will return 🙌
The conclusion of the international tournament is taking place at Twickenham Stadium in London on 27 September, just days before the 2025/26 Premiership season was due to start.
Local side Sale Sharks are sadly at the bottom of the table this current campaign, which kicked off on 5 October 2024 and ends this March, but with eyes already on the WRWC the focus for lots of players in the division will no doubt already be shifting.
Not only is the domestic women’s rugby season being delayed by nearly three whole weeks – meaning the first games won’t happen until 25 October – but this comes after the current schedule of fixtures was also reduced with player recovery in mind ahead of the World Cup.
Speaking to BBC Sport, the PWR’s operations manager, Amy Walmsley, said: “The Rugby World Cup is a generational moment for women’s rugby and will create a huge opportunity for both PWR and our clubs to grow and celebrate with their fans.
“The optimum time between the Rugby World Cup Final and our first league match will ensure we capitalise on what we already know will be the biggest and best World Cup ever, while also ensuring player welfare with adequate rest across the season.”
The stats back it up too as 2024 saw numerous milestones for the women’s game; in addition to record crowds at the Olympics, last year’s Guinness Women’s Six Nations was the most viewed on record with 8.1 million fans tuning in, not to mention an increased interest among 18-24-year-olds.
You can find the run-down of the Sale Sharks Women fixtures below:
𝗧𝗵𝗲 𝗥𝘂𝗻 𝗜𝗻
All of our fixtures for the 24/25 season are locked in. Let's bring that Northern roar to every game #SharksFamily 🦈
As for the final of the Premiership Women’s Rugby, the date has been reverted to its usual window in June, which should also fit within what congestion remains.
Nevertheless, with the Women’s Six Nations in late April and England – who have won all but one of their last 51 games – set to begin their World Cup on 22 August, the margins are still going to be somewhat fine if they are to head into the tournament in the best shape possible.
With the tickets selling extremely well, the expectation is that the Rugby World Cup final break is set to break the world record for the best-attended women’s rugby fixture in history.
In the meantime, Greater Manchester is gearing up for the men’s action as the Six Nations gets underway at the end of this month and the city is boasting the perfect place to watch it.