The NHS is launching the world’s biggest trial of a potentially life-saving blood test that can detect more than 50 types of cancer.
The Galleri test – which is already available in the US – can detect cancers that are not routinely screened for, and it can find where the disease is coming from in the body with a high degree of accuracy.
It looks for chemical changes in fragments of genetic code that leak from tumours into the blood – something done by some cancers long before symptoms even appear.
Around 140,000 volunteers in eight areas of England will be recruited to try the Galleri test.
The eight areas involved in the trial will be right here in Greater Manchester, as well as Cheshire and Merseyside, the North East, West Midlands, East Midlands, East of England, Kent and Medway, and southeast London.
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The NHS trial – which is being led by the Cancer Research UK and King’s College London Cancer Prevention Trials Unit, together with Grail that developed the Galleri test – will invite people from different backgrounds and ethnicities who are aged between 50 and 77 to take part, providing they have had a cancer diagnosis in the last three years.
Blood samples will be taken at mobile testing clinics across the eight areas over the coming weeks, in 12 months’ time, and again in two years.
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The first results are expected by 2023 and, if successful, the test could be in use from 2024.
Today the NHS launches the world’s largest trial of a revolutionary blood test which detects over 50 types of cancer before symptoms appear.
The test is said to have been especially effective at finding cancers that are more difficult to identify early, such as head and neck, bowel, lung, pancreatic, and throat cancers – but it cannot detect all cancers.
For this reason, it would not replace NHS screening programmes such as those for breast, cervical, and bowel cancer.
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The NHS said the test could play a major part in the health service’s ambition to catch 75% of cancers at an early stage, which is when they are easier to treat.
Speaking as the test trial launches, Amanda Pritchard – Chief Executive at the NHS – said: “This quick and simple blood test could mark the beginning of a revolution in cancer detection and treatment here and around the world.
“By finding cancer before signs and symptoms even appear, we have the best chance of treating it and we can give people the best possible chance of survival.”
Around 140,000 volunteers in eight areas of England will be recruited to try the Galleri test / Credit: WallpaperFlare
Professor Peter Sasieni – director of the unit and one of the trial’s lead investigators – added: “The test could be a game-changer for early cancer detection and we are excited to be leading this important research.
“Cancer screening can find cancers earlier when they are more likely to be treated successfully, but not all types of screening work.”
Featured Image – Pxfuel
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Full list of road closures set to be in place for Manchester Day 2024
Emily Sergeant
Manchester Day is back for 2024 this weekend, and the full list of road closures set to be in place has been confirmed.
Now that schools are officially out across Greater Manchester, and the summer holidays are well and truly here, the hugely-popular Manchester Day is making a return once again this Saturday 27 July, and as always, it’s set to be “the day summer officially starts” in the city centre – with a massive celebration of “all things Mancunian” on the cards.
The theme of this year’s annual event is ‘Let The Games Begin’, and it’s inspired by the international summer of sport, just 2024 Olympics kicks off over in Paris.
The day will be packed full of free events and activities to get involved with.
Some city centre roads will be closed on Friday 26 and Saturday 27 July for Manchester Day.
These will include:
🛣️Deansgate 🛣️St Ann Street 🛣️St Mary’s Gate 🛣️Market Street 🛣️King Street
— Manchester City Council (@ManCityCouncil) July 21, 2024
But of course, in order for the all the fun to go ahead as safely as possible, and as tends to be the case for events like these, Manchester City Council says it will need to make some temporary road closures to facilitate it.
The full list of road closures has now been confirmed by the Council, and there’s some major city centre thoroughfares set to be out of action.
Here’s everything you need to know.
Manchester Day is back for 2024 to celebrate the international summer of sport / Credit: Manchester City Council
Manchester Day 2024 – Road Closures
Saturday 27 July
From 6am to 11:59pm, Manchester City Council has confirmed that the following roads will be closed:
Deansgate (Manchester Cathedral to John Dalton Street) – access will be maintained to Marks and Spencer’s car park and Number One Deansgate.
St Ann Street (Deansgate to Cross Street)
St Mary’s Gate (Exchange Street to Deansgate)
St Mary’s Street (Southbridge Street to Deansgate)
Market Street (Exchange Street to Cross Street)
Fennel Street (Corporation Street to Cathedral Street) – access will be maintained for morning deliveries only.
Cathedral Street (Fennel Street to Exchange Square) – access will be maintained for morning deliveries only.
Cateaton Street (Exchange Square to Deansgate)
Barton Square (St Ann’s Square to St Ann Street)
King Street (Cross Street to Deansgate) – no access for deliveries.
All accessible bays, bus lanes, and taxi ranks within the closed areas will also be suspended during from 6pm on Friday 26 July to 11:59pm on Saturday 27 July.
The parking suspensions set to be in place are:
Deansgate (Manchester Cathedral to John Dalton Street)
St Ann Street – including the bays outside St Ann’s Church (Deansgate to Cross Street)
St Mary’s Gate (Exchange Street to Deansgate)
St Mary’s Street (Southbridge Street to Deansgate)
Southgate (St Mary’s Street to King Street West)
Market Street (Exchange Street to Cross Street)
Fennel Street (Corporation Street to Cathedral Street) – access will be maintained for morning deliveries only.
Cathedral Street (Fennel Street to Exchange Square) – access will be maintained for morning deliveries only.
Cateaton Street (Exchange Square to Deansgate)
Victoria Street (Cathedral Approach to Deansgate)
Todd Street (Corporation Street to Station Approach)
King Street (Spring Gardens to Southgate)
South King Street (Ridgefield to Deansgate)
Barton Square (St Ann’s Square to St Ann Street)
King Street West (Deansgate to St Mary’s Parsonage)
St James’s Square (John Dalton Street to South King Street)
Cross Street (King Street to Corporation Street)
Museum Street (Peter Street to Windmill Street)
Marsden Street (Cheapside to Brown Street)
Manchester Day 2024: Let The Games Begin! will take over the city centre on Saturday 27 July from 12pm-6pm.
Check out everything you need to know ahead of the event here.
‘Complex’ Metrolink repairs to the Rochdale via Oldham line could take weeks to complete
Emily Sergeant
Work currently underway on the Rochdale via Oldham line is expected to take several weeks to complete.
Transport for Greater Manchester (TfGM) has confirmed that land movement affecting the Metrolink network near Derker has now “slowed”, and this means that detailed ground investigations and temporary repair works have been able to get underway.
In order for trams to run again on the crucial line from the city centre to the two major Greater Manchester towns, TfGM says that a small section of track has to be moved back – also known as ‘slewed’ – into its original position.
The overhead line poles also need to be repaired too, the transport operator revealed.
Rochdale line update
Land movement affecting the Metrolink network near Derker has slowed, enabling detailed ground investigations and temporary repair works to get underway.
To get trams running again, a small section of track has to be moved back into its original position… pic.twitter.com/byERjitdi1
Unfortunately though, due to the “complex” nature of these works, and despite the fact that TfGM says it’s actively looking to “accelerate” the repairs, the project is expected to take up to five weeks to complete in full.
On top of this, the detailed ground investigations will also establish whether any further work to strengthen foundations beneath the track will be needed at a later date.
TfGM has apologised for the inconvenience caused to passengers.
‘Complex’ Metrolink repairs to the Rochdale via Oldham line could take weeks to complete / Credit: TfGM
Speaking on the scale of works currently underway, and how long he expects them to continue for, Pete Sommers, who is TfGM’s Network Director for Metrolink, said: “I’m sorry for the impact this is having, and will continue to have, on people’s journeys.
“We are working to get trams running through the area again, but this remains a complex and challenging issue and it could still be a few weeks before this happens.
“We will of course keep passengers updated, and I’d encourage people to check our social media channels and website for the latest information and advice.”