The NHS is launching the world’s biggest trial of a potentially life-saving blood test that can detect more than 50 types of cancer.
The Galleri test – which is already available in the US – can detect cancers that are not routinely screened for, and it can find where the disease is coming from in the body with a high degree of accuracy.
It looks for chemical changes in fragments of genetic code that leak from tumours into the blood – something done by some cancers long before symptoms even appear.
Around 140,000 volunteers in eight areas of England will be recruited to try the Galleri test.
The eight areas involved in the trial will be right here in Greater Manchester, as well as Cheshire and Merseyside, the North East, West Midlands, East Midlands, East of England, Kent and Medway, and southeast London.
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The NHS trial – which is being led by the Cancer Research UK and King’s College London Cancer Prevention Trials Unit, together with Grail that developed the Galleri test – will invite people from different backgrounds and ethnicities who are aged between 50 and 77 to take part, providing they have had a cancer diagnosis in the last three years.
Blood samples will be taken at mobile testing clinics across the eight areas over the coming weeks, in 12 months’ time, and again in two years.
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The first results are expected by 2023 and, if successful, the test could be in use from 2024.
Today the NHS launches the world’s largest trial of a revolutionary blood test which detects over 50 types of cancer before symptoms appear.
The test is said to have been especially effective at finding cancers that are more difficult to identify early, such as head and neck, bowel, lung, pancreatic, and throat cancers – but it cannot detect all cancers.
For this reason, it would not replace NHS screening programmes such as those for breast, cervical, and bowel cancer.
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The NHS said the test could play a major part in the health service’s ambition to catch 75% of cancers at an early stage, which is when they are easier to treat.
Speaking as the test trial launches, Amanda Pritchard – Chief Executive at the NHS – said: “This quick and simple blood test could mark the beginning of a revolution in cancer detection and treatment here and around the world.
“By finding cancer before signs and symptoms even appear, we have the best chance of treating it and we can give people the best possible chance of survival.”
Around 140,000 volunteers in eight areas of England will be recruited to try the Galleri test / Credit: WallpaperFlare
Professor Peter Sasieni – director of the unit and one of the trial’s lead investigators – added: “The test could be a game-changer for early cancer detection and we are excited to be leading this important research.
“Cancer screening can find cancers earlier when they are more likely to be treated successfully, but not all types of screening work.”
Featured Image – Pxfuel
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Almost Famous announce they are closing their Withington restaurant in candid statement
Danny Jones
The unfortunate hospitality news just keeps coming, it seems, as Almost Famous have announced they will soon be closing their Withington restaurant.
A staple of the Manchester foodie scene for over a decade now and with a growing empire across the North, the ‘dirty burger’ pioneers aren’t just one of the most recognisable restaurant names in Greater Manchester, they’re tastemakers and have been for years.
However, unlike the OG site in the Northern Quarter which first began blowing burger fans away back in 2012, their Great Northern Warehouse venue or their locations in Leeds, Almost Famous‘ Withington site simply isn’t working.
In truth, their most recent restaurant and fifth all-told had been struggling for a while and it was only back in May that they were thanking customers for helping them ‘pull through’ a rough patch, but it seems they’ve sadly slumped back into being quiet and can no longer continue in this fashion.
Explaining in the lengthy and clearly emotional statement, beloved owner Beau Myers wrote: “Announcement (sad sh***y one, sorry).
Sorry to say we will be closing the Withington branch of Almost Famous. It’s not working, we’re not busy enough and it’s dragging us down.
“Really sorry to disappoint you guys, we’ve tried and we’ve pushed and you’ve been amazing for supporting us, this just isn’t the one. Sometimes you have to hold your hands up, admit you f****d up, learn from your mistakes limit the damage and move on.
“We got sucked in with perhaps the most beautiful site ever in the wrong location (for us). It really is/was my fav[ourite] famous and I’m gutted it’s closing, it looks the coolest, we had the staff party there this year. I wish some of the art wasn’t straight on the wall so we could take it with us.”
Almost Famous Withington will be closing after their final dinner service next weekend. (Credit: The Manc Group)
They go on to add: “We will be closing after service on Sunday 22nd (next weekend). Please come down and say goodbye and enjoy this beautiful place one last time before it goes forever. There will be drinks and tears and laughs.
Having visited the particular branch a few times ourselves not only in a work capacity but in our own personal time, we can confirm the Withington restaurant had a special charm to it and we’re also very sad to see it go.
It goes without saying that the comments were filled with support, with one person writing, “This is so sad I’m so sorry: you’ve tried really hard. Sad loss for Withington”, and another adding, “Always sad when a place with friendly staff, serving good food, good drinks and at a reasonable price doesn’t make it… onwards and upwards.”
RIP Almost Famous Withy — we hope you come back one day soon and we’re sure the whole team will bounce back stronger than ever no matter what comes next for the much-loved brand.
The hearing over Manchester City’s 115 FFP charges will officially start next week
Danny Jones
After more than a year of speculation as to when proceedings will finally start, it has been confirmed that the hearing regarding Manchester City and their 115 FFP charges is set to begin next week.
Man City were first slapped with the laundry list of alleged breaches of FFP (financial fair play) and failure to comply with Premier League rules on profit and sustainability (PSR) back in February 2023, but little movement on the case has been reported since then.
In that time, they also won the coveted Treble and their record-breaking fourth league title in a row; meanwhile, the club have continued to deny all claims of rule-breaking.
However, it has now been revealed that City‘s hearing will now kick off on Monday, 16 September.
BREAKING: The hearing over Manchester City's 115 charges will start on Monday 🚨 pic.twitter.com/9ujOCryVMF
As explained in various reports, given the extended nature of the claims made against the Manchester side, it is estimated that the case could run on for up to two months if not longer.
Furthermore, it is thought a decision isn’t expected to arrive until spring 2025 – again, this is simply due to the number of charges brought up over the best part of a decade.
In case you need a refresher, the allegations levelled at Man City date back to 2009 and concern a supposed nine years of financial irregularities, as well as subverting UEFA FFP rules.
Some of the accusations made against them also include failing to cooperate with the European football body and the Premier League, as well as offering ‘secret contracts’ so as to pay one particular manager a larger sum than what they recorded in their financial statements.
The final verdict, whenever it is reached, will be handed down by an independent commission and City will still be able to make an official appeal.
It goes without saying that were they to be found guilty, it would be the biggest financial scandal in English football history and could be seismic for the future of money in the sport and regulations surrounding ownership, which have already grown tighter following the charges being issued.
And in case you needed a more detailed refresher on what exactly they are being tried for and what the possibilities are regarding punishment if found guilty, here’s a quick rundown:
The Manc -
13th September 2021 
