On Monday, news filtered through that the vaccine being developed by Pfizer and BioNTech is 90% effective - with zero safety concerns raised during its testing phase during which it was used on 43,500 people.
The sensation of relief that swept the country on Monday was understandable.
During the afternoon, news filtered through that a vaccine being developed by Pfizer and BioNTech has been confirmed to be 90% effective – with zero safety concerns raised from its testing phase during which it was used on 43,500 people.
This is as close as we’ve been to the prospect of immunisation since the pandemic took hold.
Chief Medical Officer Chris Whitty called the news “very encouraging”, whilst Deputy CMO Jonathan Van-Tam even suggested there could be a vaccine by Christmas – with a “much better horizon by spring.”
Preliminary news that the Pfizer/BioNTech vaccine is effective demonstrates the power of science against COVID. We must see the final safety and efficacy data, but it is very encouraging.
It is essential we continue to suppress COVID, but it is a reason for optimism for 2021.
Prime Minister Boris Johnson – who himself must have been buoyed by the very real prospect of a magic jab after a torrid few months leading the nation – urged caution.
He warned it was still “very, very early days”, and that “the biggest mistake we could make now would be to slacken our resolve at a critical moment.”
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Van Tam also admitted that setbacks during the distribution of a vaccine could easily happen, and attempted to clarify the situation with a football analogy.
“[We] haven’t won the cup yet, but what it does is it tells you that the goalkeeper can be beaten,” he said.
Here’s what we know about the new vaccine so far…
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How does the vaccine work?
The Pfizer and BioNTech vaccine works by teaching the immune system to combat coronavirus.
Two doses are required – three weeks apart – for maximum effect.
The vaccine involves injecting people with a tiny bit of the virus which the immune system immediately recognises as a threat and learns how to defeat; thereby offering future protection.
According to developers, 9 out of 10 people who receive the vaccine will not get COVID symptoms.
Who will get it first?
The most vulnerable people in the UK will have first dibs on any vaccine.
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This means it’s likely to be distributed to care homes and hospitals – locations the virus has hit hardest.
Frontline workers may also be prioritised for doses.
The expectation is that the older you are, the sooner you will be eligible for the coronavirus vaccine.
Younger people are likely to be lower down the list unless they have a condition that categorises them as vulnerable.
But the answer as to whether the vaccine will work in the long-term is a case of wait and see.
There are apparently some logistical challenges to storing the vaccine, too – with doses having to be kept at -80 degrees (facilities a humble GP surgery or pharmacy would not have).
The virus may also mutate later down the line, which would mean the vaccine would have to be tweaked in order to remain effective.
When will lockdowns stop?
Once the vaccine is ready, the challenge is getting it to the people who need it most.
This will take time, and until then, social restrictions remain of crucial importance in the fight against COVID-19.
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Is the UK getting the Pfizer and BioNTech vaccine?
Yes.
Britain has ordered 30 million doses.
What about other vaccines?
There are around a dozen vaccines in the final stages of development – with news expected on these in the coming weeks and months.
However, the Pfizer vaccine appears to be the lead candidate.
The BBC’s Health and science correspondent, James Gallagher, stated: “We are still waiting for the full data, but these results are even better than people were hoping for.
“A good flu vaccine protects around half of people, so 90% at the first attempt is a triumph.”
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No trams to run on three major Greater Manchester lines this Easter bank holiday weekend
Emily Sergeant
People are being urged to ‘plan ahead’ as no trams are set to run on three major Greater Manchester Metrolink lines this weekend.
As part of a continuing £150 million investment in the Metrolink network across the region, Transport for Greater Manchester (TfGM) has announced that more than 1km of track will be replaced on the Altrincham line, and work will also take place between Trafford Bar and Deansgate-Castlefield to prepare for full track replacement later in the year.
As a result, there will be no trams on the Altrincham, Eccles, and Trafford Park lines this Easter bank holiday weekend all day from Friday 3 to Monday 6 April.
On top of these line closures, there is also set to be disruption across other parts of the network too, as on the East Didsbury and Manchester Airport lines, trams will run to Firswood only, and services on the Rochdale line will terminate at Exchange Square.
To keep people moving over the four-day weekend, replacement buses will run between all the affected stops, TfGM has confirmed.
Anyone using a replacement bus, however, will still need a valid Metrolink ticket or a one-day Bee bus ticket to travel, and customers will be able to use all existing options to buy these, as they will not be able to buy a ticket or pay for the fare on the replacement buses themselves.
No trams will be running on three major Greater Manchester lines this Easter bank holiday weekend / Credit: TfGM
Replacement buses are said to be calling at ‘all affected stops’ along the lines, so customers are being told not to worry about that.
Speaking ahead of the improvement works being carried out this weekend, Ian Davies, who is the Network Director for Metrolink at TfGM, said: “The first main upgrades of the year get under way over the Easter weekend, as our £150m programme to improve our network continues.
“We’ll be doing everything we can to minimise disruption to passengers while we carry out this essential work to ensure our tram network remains reliable, resilient and safe for years to come.”
TfGM has assured that staff will be out and on-hand across the network this weekend, but is urging anyone travelling to plan for their journeys ahead of time to make sure they go as smoothly as possible.
Looking ahead to the rest of the month, no trams will run between Piccadilly Gardens and Ashton-under-Lyne on Saturday 11 and Sunday 12 April while the track is repaired, and a further weekend closure for track repairs on the Ashton line will take place on Saturday 25 April and Sunday 26 April.
Find out more and plan ahead on the Bee Network’s dedicated webpage here.
Featured Image – Janus Boye
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Three men arrested after ‘shocking’ Salford pub fight leaves victim in life-threatening condition
Emily Sergeant
Three men have been arrested as police continue to appeal following a ‘shocking’ incident in Salford over the weekend.
Greater Manchester Police (GMP) explained that, at around 2:51am yesterday (Sunday 29 March), officers were called to reports of an assault at a pub on Liverpool Road in Irlam, where it’s understood that an incident involving several males took place.
Police quickly attended the scene, and one male was rushed to hospital.
The man sustained serious injuries and was taken to hospital for treatment, where he’s said to remain in a life-threatening condition.
While officers are working ‘at speed’ on their investigation to establish the full circumstances of this incident, a scene is currently in place, and road closures are affecting the immediate area.
At this time, it has been confirmed that three men – all in their 20s – have been arrested on suspicion of Section 18 assault, and they remain in custody for further questioning while GMP renews its public appeal for information.
“This is a shocking incident and our thoughts are firmly with the victim and his family during this extremely difficult time,” commented Detective Chief Inspector Helen Bagnall, from GMP’s Salford district. “We are working at pace and remain absolutely committed to identifying everyone involved and bringing those responsible to justice.
“Three arrests have been made in connection with this incident, and we are continuing to appeal for further information.
“Officers remain committed to understand the full circumstances and are urging anyone with information to come forward to support our investigation.”
Can you help? A dedicated online Major Incident Public Portal has been set up, and information, CCTV, dashcam, doorbell, and phone images and footage can be submitted here, or you can also contact police on 101, quoting log 256 of 29/03/26.
Alternatively, you can contact Crimestoppers, anonymously, on 0800 555 111.