In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they’re the only organ in humans that regenerates automatically and regularly, even if they haven’t been injured – and it’s from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles – including stem cells – divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
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But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: “In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
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Scientists have discovered a potential cure for baldness thanks to new research / Credit: Tengyart (via Unsplash)
“In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing.”
“TGF-beta has two opposite roles,” Wang added.
“It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death.”
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While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it’s a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it’s the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: “Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle.”
Of course, there’s still some way to go until baldness is cured – however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
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“Potentially, our work could offer something to help people suffering from a variety of problems,” Wang concluded.
Erling Haaland dresses up as Santa and hands out Christmas presents in Greater Manchester
Danny Jones
Manchester City star Erling Haaland has doubled as Father Christmas in his latest YouTube stunt, dressing up as Santa and handing out presents to local kids in the new episode.
We’re starting to think he might be one of the most likeable footballers on the planet right now.
The Norwegian footballer recently surpassed Alan Shearer’s ‘fastest to 100 goals record’ in the Premier League and has been well and truly back to his best as Man City continue to rediscover their form, but the big blonde number nine has been delighting both on and off the pitch of late.
For starters, even before any of the season’s givings began, we got the giggle just from our first glimpse of the thumbnail.
Yes, Haaland definitely has a habit of leaning into the humorous side of his celebrity status, having already dressed up as the Joker for Halloween in one of the first episodes published on his still relatively new YouTube channel.
However, the 25-year-old got up to some more heartwarming activities this time around, swapping the face paint, green wig and stripey suit for a red coat, hat, some little glasses and a big white beard.
With the video itself showing him getting into character and loading his car with a sack full of presents, he then goes on to visit multiple houses to dish out the surprise gifts.
While the title and description state that he drove around the streets of 0161, it’s hard to tell where exactly he went, but we’d guess it was more around Alderley Edge and/or the Cheshire side of the Greater Manchester borders.
One particular interaction between the disguised Blue and a young Red certainly produced a harmless little bit of comedy…
Either way, on the whole, this particular instalment was more wholesome than it was funny, and it’s always nice to see sports personalities and famous people spreading kindness.
Obviously, not everyone can afford to be as generous as a Premier League and world-famous international athlete, but it’s nevertheless a nice touch.
Featured Images — Erling Haaland (screenshots via YouTube)
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Kobbie Mainoo’s brother sends three-word message to Man United after Old Trafford stunt
Danny Jones
Kobbie Mainoo’s brother, Jordan Kwadwo Osei Mainoo-Hames, has caused quite a stir online after sending a simple but definitive three-word message to Manchester United and head coach Ruben Amorim, in the form of a publicity stunt.
In case you missed the blockbuster eight-goal thriller at Old Trafford on Monday night, the scoreline wasn’t the only headline on the night.
Man United managed to give up their one-nil lead right on two separate occasions, and despite clawing their way back to 4-3 with just over 10 minutes of regulation time left on the clock, ultimately went on to concede an equaliser in the 84th minute.
Despite Kobbie Mainoo’s receiving a rapturous round of cheers and applause when he was subbed on in the second half, not to mention adding some real dynamism in the middle of the park, any notion of his contribution has now been overshadowed by his sibling.
As you can see, Jordan Mainoo-Hames – who found fame after appearing on series five of reality TV show Love Island (2019) – took the opportunity to capitalise on the ongoing narrative regarding Kobbie and his relationship with the current United boss.
For months now, there has been much speculation around whether the Stockport-born youth product will stay at his boyhood club or leave in the next couple of transfer windows, given that he’s only been afforded limited minutes under the Portuguese manager.
Amorim, who has collected just 24 Premier League points since arriving last November, maintains that he recognises Mainoo’s but, crucially, sees him as competing for the same position as Bruno Fernandes.
Now a model for a number of big brands, he’s no stranger to posing in clothes, but in this case, it all centred around a simple black t-shirt simply reading ‘Free Kobbie Mainoo’ in plain white text, seemingly imitating Nike’s ‘Just Do It’ font.
Safe to say that despite catching the eye of plenty in and around the stadium, as well as countless more online, it hasn’t gone down particularly well with a good chunk of the supporters.
Even neutrals have hopped on social media to label the stunt everything from “embarrassing” and causing an “unnecessary” distraction to urging the 20-year-old to distance himself from the stunt and/or his half-brother.
Utter nonsense. His brother turning up at Old Trafford in a ‘Free Kobbie Mainoo’ tee is pure embarrassment. Clout-chasing disguised as support, when the player’s interests should be the priority. We’ve seen this playbook from families before… https://t.co/9p5uognVsX
For many fans, the incident was reminiscent of the Alejandro Garnacho situation: another promising youngster whose family’s outspoken nature on social media, along with his own, ultimately soured his relationship with Amorim to the point of leaving the club this past summer.
Rather notably, Garnacho ruffled even more feathers earlier this month after responding to a question about any potential regrets over how his time at the club ended…
As for his former fellow academy graduate, it is looking increasingly likely that he may at least leave on loan this January in search of more regular football, especially with the 2026 World Cup looming.
Whether you’re a Red or not, we’re interested to hear what you make of the whole mess. Let us know down in the comments.
You can see the highlights from the frankly bonkers game against Bournemouth down below.
Emily Sergeant -
26th July 2022 
