In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they’re the only organ in humans that regenerates automatically and regularly, even if they haven’t been injured – and it’s from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles – including stem cells – divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
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But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: “In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
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Scientists have discovered a potential cure for baldness thanks to new research / Credit: Tengyart (via Unsplash)
“In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing.”
“TGF-beta has two opposite roles,” Wang added.
“It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death.”
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While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it’s a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it’s the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: “Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle.”
Of course, there’s still some way to go until baldness is cured – however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
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“Potentially, our work could offer something to help people suffering from a variety of problems,” Wang concluded.
Tommy Fury vs Darren Till press conference descends into foul-mouthed chaos
Danny Jones
The first press conference ahead of Tommy Fury vs Darren Till was held on Tuesday evening and it didn’t take long for the whole thing to descend into absolute bedlam.
Having only been confirmed on Sunday, Fury vs Till will be a homecoming bout for the Wythenshawe-born fighter who is set to headline the first-ever boxing match at Manchester’s Co-op Live arena.
With the date set for 18 January, the pre-fight build-up and media frenzy are growing fast and things have already come to ahead in just the first meeting between the two fighters in London this week.
Clearly sharing plenty of bad blood already, while Tommy and Till were engaging in the usual fighting talk, the family patriarch, John Fury, decided to interject and it was at this point that things boiled over.
‼️ Tommy Fury vs Darren Till press conference descends into chaos as Till tells John Fury: "Shut up, you haven't been seen since Oleksandr Usyk battered Tyson."
As you can see, amidst the various insults being thrown around regarding intelligence, boxing ability, Tommy’s older brother Tyson being “battered by [Oleksandr] Usyk”, ‘Big John’ then launches a bottle of water across the table at Till, sparking a hot-tempered on-stage skirmish.
The lengthy exchange features as many expletives as you could imagine, with 31-year-old Darren Till also threatening that he will “bladder” both Tommy and his more established heavyweight sibling Tyson, labelling the entire Fury family “shithouses” as they walk out of the London press conference.
A mixed martial artist by trade who has competed at both welterweight and middleweight in the UFC, Till assured that even if the boxing match isn’t going his way on the night, he will kick [him] square in [the] face”, adding that he’s a “proper fighter” and that Tommy, on the other hand, has no power.
YouTube turned musician and occasional boxer, KSI – the founder of the Misfits promotion who is putting on the event and who Fury beat back in October last year – can also be heard whooping from centre stage and shouting, “Get your tickets!”
Even after the mini-brawl is separated, the foul-mouthed back and forth continues for some time. You can see another angle here:
Press conference aftermath 🤯@darrentill2 was going IN on the Fury’s 😳
This isn’t the first time things have boiled over at a Fury press conference; in fact, it’s not even the first time John Fury, 59, has found himself in the very eye of the storm.
Meanwhile, the youngest Fury son is preparing first his first fight in over a year, having nearly joined this year’s I’m a Celeb lineup instead.
Tickets for the now highly-anticipated boxing match at Co-op Live, just the second combat sports event to have been held at the arena, are on sale now – you can grab yours HERE. It’s going to be a feisty one.
Festive Grinch-themed cafes to pop up inside Greater Manchester Primark stores
Emily Sergeant
Festive Grinch-themed cafes are popping up inside two of Primark’s biggest Greater Manchester stores in the run-up to Christmas.
As the temperatures turn colder by the day, the nights draw in, and the most wonderful time of the year nears closer and closer, it won’t be long before it’s time to snuggle up in our comfies and pop on the first Christmas film of the year – and for some of us, there’s a good chance that first film of choice will be The Grinch.
Whether you prefer the 2000 fantasy comedy starring Jim Carey, or the 2018 animated reboot with Benedict Cumberbatch, it’s undoubtedly a real family favourite.
To celebrate everyone’s favourite grumpy green grouch, Primark has teamed up with Dr. Seuss once again on a Grinch-tastic collaboration.
Festive Grinch-themed cafes have popped up inside Greater Manchester Primark stores / Credit: Supplied
Shoppers can now head to their nearest Primark store to find the largest-ever Grinch collection, with something for the whole family, as well as great gifting options said to be “ideal for getting into the anti-Christmas spirit”.
There’s Grinch pyjamas and slippers for both adults and kids, a Grinch ‘Onesie’ that’s sure to make people green with envy, Grinch drinks cups and mugs, a selection of loungewear and Christmas jumpers for festive dressing, and so much more, as well as whole host of Grinch-inspired outfits and toys for your four-legged friends too.
As part of Primark’s aim to offer affordable choices for everyone, prices for the Grinch collection start at just £1 for accessories, and go up to £24 for adult clothing.
If the return of the Grinch collection wasn’t exciting enough as it is, the all-new Grinch cafes – which are popping up in Primark on Market Street in Manchester city centre, as well as Primark in Trafford Palazzo – are bound to be hit with fans of the furry character.
There’s everything from green waffles and themed milkshakes, to festive toasties, hot drinks, and more on the menu.
With Greater Manchester Grinch cafes set to be open until the end of December, Sarah Jackson – who is the Director of Licensing at Primark, said: “We’re so excited to roll out our amazing cafe experience across a number of our UK locations, bringing a sprinkle of mischief to our customers this festive season.
“Whether you’re stopping in for a sweet treat or stocking up on pyjamas and gifts for the whole family, we have everything you need to make it a truly unforgettable Grinch-mas.”
Emily Sergeant -
26th July 2022 
