In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they’re the only organ in humans that regenerates automatically and regularly, even if they haven’t been injured – and it’s from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles – including stem cells – divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
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But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: “In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
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Scientists have discovered a potential cure for baldness thanks to new research / Credit: Tengyart (via Unsplash)
“In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing.”
“TGF-beta has two opposite roles,” Wang added.
“It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death.”
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While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it’s a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it’s the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: “Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle.”
Of course, there’s still some way to go until baldness is cured – however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
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“Potentially, our work could offer something to help people suffering from a variety of problems,” Wang concluded.
Mancs wanted to take part in a new series of the ‘hardest quiz show on TV’
Emily Sergeant
Call yourself a clever clogs? The BBC is currently looking for contestants to take part in what is widely considered the hardest quiz show on TV.
That’s right – Only Connect is back for another series on BBC Two.
Presented by Victoria Coren Mitchell and first broadcast all the way back in 2008, Only Connect takes TV quizzing to the next level, as it sees two teams compete against each other by finding connections between seemingly unrelated clues.
In this quiz show – which viewers have dubbed one of the most challenging there is – knowledge only takes you so far, as the ability to think laterally is also deemed ‘vitally important’.
A casting call for the upcoming 2027 series has been shared on the BBC website, with people from Greater Manchester encouraged to apply.
Mancs wanted to take part in a new series of the ‘hardest quiz show on TV’ / Credit: BBC
The casting call reads: “The popular BBC Two quiz show presented by Victoria Coren Mitchell returns for a new series in 2027.
“Only Connect is seeking teams of three players OR single applicants or teams of two looking for like-minded teammates to pool their combined wits to solve fiendish conundrums and vexing puzzles.
“This is the quiz series where, as in life itself, knowledge will only take you so far: patience and lateral thinking are also vital. It’s all about making connections between things which may appear, at first glance, not to be connected at all.”
Reckon you’ve got what it takes then? Applications are now open, and all applicants must be aged 18 or over and a resident in the UK or Channel Islands.
Massive student night returns to Trafford Centre next month with up to 50% off on big brands
Emily Sergeant
Students can get themselves up to 50% off on food, activities, and loads of big-name brands at the Trafford Centre next month.
With thousands of new and returning students starting to arrive for the new academic year at Greater Manchester‘s universities, one of the region’s biggest student nights will be making a long-awaited comeback for one night only next month – and there’ll be loads of exclusive offers and free entertainment to make the most of across the evening.
Taking over the Trafford Centre in early October, the popular one-off student night is happening in partnership with Student Beans, and gives cash-strapped students the chance to shop a variety of incredible discounts all under one roof.
Just some of the big brands offering big discounts include 25% off at Levi’s and Boux Avenue, 20% off at Gymshark, Hollister and Abercrombie & Fitch, and 15% off at KIKO, Rituals, and Sephora.
It’s not just retail brands you’ll be able to save some pennies on either, as many of the Trafford Centre’s restaurants and cafes will also be offering discounts and freebies on the night too.
Alongside the offers, students can expect plenty of live entertainment and in-store experiences throughout the evening, including a DJ set and drinks at Calvin Klein, in-store fitness challenges and at Gymshark, an exclusive piercing event at Lovisa, and a Beauty Hub takeover at Sephora.
There’ll also be ‘spin-to-win’ opportunities at places like schuh, River Island, and YO! Sushi.
Massive student night returns to Trafford Centre next month with up to 50% off on big brands / Credit: Supplied
“Student Night is one of the highlights of our autumn calendar, and we’re excited to welcome students for an evening of brilliant offers and feel-good experiences,” explained Simon Layton, who is the Centre Director at the Trafford Centre.
“Whether they are updating their wardrobe, stocking up on beauty favourites, grabbing a bite to eat or enjoying the atmosphere with friends, there is plenty to discover across the centre.
“With simple transport links from Manchester city centre and across the region, Trafford Centre is the perfect place for a student night out.”
The Trafford Centre’s Student Night is happening on Thursday 1 October from 6-10pm, and students can now reserve themselves a spot by registering online HERE.
Emily Sergeant -
26th July 2022 
