In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they’re the only organ in humans that regenerates automatically and regularly, even if they haven’t been injured – and it’s from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles – including stem cells – divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
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But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: “In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
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Scientists have discovered a potential cure for baldness thanks to new research / Credit: Tengyart (via Unsplash)
“In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing.”
“TGF-beta has two opposite roles,” Wang added.
“It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death.”
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While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it’s a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it’s the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: “Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle.”
Of course, there’s still some way to go until baldness is cured – however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
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“Potentially, our work could offer something to help people suffering from a variety of problems,” Wang concluded.
Academy graduate Oscar Bobb is leaving Manchester City on a permanent transfer
Danny Jones
Manchester City youth academy graduate Oscar Bobb is leaving the club after sealing a move to Fulham FC.
Despite plenty of loan interest throughout the January transfer window, the Man City attacker has secured a switch to the in-form West London team on a permanent basis.
Bobb looked increasingly likely to leave in some capacity following the arrival of another winger in the form of instant hit, Antoine Semenyo, but it now looks as though his departure is all but confirmed, bar an imminent official announcement.
As reported by Italian journalist Fabrizio Romano, the agreement has now been reached between the two clubs pending a full medical today (Thursday, 29 January).
According to Romano, Fulham will pay Man City approximately £27 million for Bobb’s services, who becomes the latest addition in what has already been a fairly busy period of recruitment.
He goes on to add that “City also mantain [a] 20% sell-on clause, matching rights and future control on the player based on his decision.”
There is no suggestion of a buy-back clause at this time, but given his age and having already made a fair few appearances for Pep Guardiola‘s first team, it wouldn’t be beyond the realms of possibility to see him return to the club one day.
Bobb also arrives at Craven Cottage following the exit of multiple wingers and offensive options, including Adama Traore, ex-Man United product Andreas Pereira and Arsenal youngster, Reiss Nelson, whose loan deal has expired and has signed another temporary deal at local rivals, Brentford.
Had it not been for that injury I know he would’ve been class for City for a long time, and let’s not forget that goal v Newcastle pic.twitter.com/inGxi5UjPM
The young Norwegian winger joined the Etihad Campus back in 2023 and went on to contribute a handful of goals and assists, despite limited appearances and some very unfortunate injury issues.
Only seven months ago, his soon-to-be former parent club released a short video charting his return from the sidelines after fracturing his leg – a setback which kept him out for roughly five months.
Plenty of fans have quickly placed him in the so-called ‘what if?’ category of players, and given that he’s still just 22 years old and has already impressed on a number of ocassions for such a big club, we wouldn’t be surprised if he goes on to have a very exciting career.
Can you see the Blues bringing in or letting anyone else go before deadline day?
McDonald’s is set to axe 80% of its vegan and vegetarian options in the UK
Emily Sergeant
McDonald’s is set to remove nearly all of its vegan and vegetarian options from the UK menu, according to reports.
We may be in what is known to some as Veganuary, but one of the world’s leading fast food chains has reportedly made the decision to drastically cut back on the selection of plant-based and meat-free options on its UK menu, appearing to align with the trends that show a decline in veganism overall.
McDonald’s is known for offering those who choose not to eat meat a choice of different options – from its Veggie Dippers to the popular McPlant burger.
But from the start of next month, only one options is apparently set to remain on the menu.
In a decision that seems to already be making fans on social media ‘furious’, McDonald’s has revealed that it will stop selling Veggie Dippers, Veggie Dipper Happy Meals, Spicy Veggie Wraps, and Vegetable Deluxe sandwiches.
McDonald’s is set to axe 80% of its vegan and vegetarian options in the UK / Credit: McDonald’s UK
All that remains will be the vegan McPlant Burger – which McDonald’s says still remains popular with steady sales.
According to reports in various outlets like the Daily Mail and Sky News, McDonald’s says it had reviewed feedback and sales data in order to make the decision.
A spokesperson for McDonald’s UK told the Daily Mail: “We’re always listening to our customers to help inform and evolve our menu. After reviewing feedback, alongside the sales data of our Veggie Dippers, it’s clear this product does not match the appeal of McPlant for our vegetarian customers.
“That’s why we’ve made the decision to remove them from the menu, as we focus on developing better vegetarian options that meet our high standards.
The fast food chain has released a statement as to why it is reducing options / Credit: Road Ahead (via Unsplash)
“While McPlant remains a firm fan favourite and will continue to be the go-to choice for our vegetarian and vegan customers, we recognise these changes may be disappointing for some.”
If this statement is anything to go by though, it does appear that the McPlant won’t stay the only vegan option on the menu forever, as the fast food chain has indicated that it is looking at introduction others in the future.
“We are actively learning from other markets to understand which vegetarian and vegan options are proving most popular and exploring exciting new offerings that we know customers will love,” the spokesperson’s statement concluded.
The Veggie Dippers, Veggie Dipper Happy Meals, Spicy Veggie Wraps, and Vegetable Deluxe sandwiches will be removed from the McDonald’s menu in the UK on 3 February.