In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they’re the only organ in humans that regenerates automatically and regularly, even if they haven’t been injured – and it’s from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles – including stem cells – divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
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But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: “In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
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“In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing.”
“TGF-beta has two opposite roles,” Wang added.
“It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death.”
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While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it’s a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it’s the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: “Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle.”
Of course, there’s still some way to go until baldness is cured – however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
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“Potentially, our work could offer something to help people suffering from a variety of problems,” Wang concluded.
Manchester’s Club de Padel claps back at ’embarrassing’ copycat ASOS product
Daisy Jackson
A local Manchester business has sarcastically pointed out the glaring similarities between a new t-shirt on ASOS and one of its own designs.
Club de Padel has a range of retro-inspired merch with UN:IK, a small independent streetwear brand also based here in Manchester.
Its collection of t-shirts, hoodies, tracksuits, hats and bags often feature a design of an illustrated padel ball (which to the untrained eye is basically a tennis ball) in motion.
But this week a t-shirt appeared on ASOS that also featured an illustrated padel ball in motion, just in a slightly different colour palette.
The ASOS version, which has now been removed from sale, also undercut Club de Padel’s price by £6.
Since Club de Padel took the ’embarrassing’ copycat product public on their Instagram page, ASOS has launched an investigation and taken it off their website.
The sports venture, based at Deansgate Square and the only padel club in Manchester, wrote: “Love the new designs ASOS, kinda reminds us of something though…
“Ah. Well that’s embarrassing… We’ve got a new line coming soon with UN:IK Clothing you’re just gonna love ASOS.
“In the meantime we made this for you @asos, save your design team a job.”
An ASOS spokesperson said: “We take intellectual property issues very seriously and have removed this product from sale while we investigate further.”
Of the Club de Padel and UN:IK collaboration, aka the real deal, UN:IK says it has ‘served up a staple for us, retro inspired leisure pieces with Manchester’s first ever padel club’.
Club de Padel in Manchester has gone public to poke fun at ASOS
They wrote: “Inspired by owners after a trip to Spain, Club de Padel has hit the city with a wave and the lifestyle brand we have created with them reinforces the fastest growing sport across Europe.
“Our classic vintage washes and oversized fits, working with independent designs as always on this local independent partnership. Don’t be afraid to the sport, we’ll guarantee you love it as much as these clothes.”
Yorkshire Tea is Manchester’s ‘favourite’ brand of teabags, according to new data
Danny Jones
The Great British debate of which teabag is best is one that will rage on for millennia, that’s just the way it is, but according to new data, it sounds like we might at least have an answer to which brand makes for Manchester’s favourite brew.
It won’t be a surprise to many of you and we can certainly confirm it on our end but the one and only Yorkshire Tea looks to have taken the cuppa crown when it comes not only to Manchester’s preferred teabag but seemingly the best-loved in Britain as a whole.
This is according to numbers pulled by local firm, TonerGiant. The Atherton-based ink and toner suppliers decided a poll around the office wasn’t enough and instead chose to turn their knowledge of the market and consumer trends into a bit of online research.
At the end of the day, tea has got to be the most important of all office supplies, surely?
According to the stats, Yorkshire Tea is Manchester’s favourite brand of tea bags. (Credit: Yorkshire Tea)
Using data from trusted online source Statista, which nailed down the top 25 teabag brands in the UK, each make was then ranked in relation to its average monthly searches via Google Keyword Planner to reveal that Yorkshire Tea was clearly the top dog.
With roughly 390 searches per month in Manchester alone, compared to PG Tips as the next best (260), it seems us Mancs have to concede at least one thing to our fellow Northern county: Yorkshire makes a bloody good brew.
The Roses rivalry raged for centuries but if there’s one thing that brings us together, it’s a good cuppa.
In terms of other tea brands that came in high on the leaderboard, Pukka Tea (170), Twinings (140)and Teapigs (90) made up the rest of the top five most-searched tea brands in Greater Manchester. It’s also interesting to see how those figures looked when extrapolated nationwide. Here’s the full ranking:
Rank
Tea
Average UK monthly searches
1
Yorkshire Tea
27,100
2
PG Tips
18,100
3
Pukka Tea
14,800
4
Twinings
12,100
5
Teapigs
8,100
6
Whittards Tea
6,600
7
Tetley
4,400
8
Clipper Tea
4,400
9
Lipton Tea
3,600
10
Barrys Tea
3,600
11
Thompsons Tea
1,300
12
Typhoo
1,300
13
Taylors Tea
1,300
14
M&S Tea
1,300
15
Tesco Tea
1,000
16
Tick Tock Tea
880
17
Sainsbury’s Tea
720
18
Lyons Tea
720
19
Asda Tea
590
20
Aldi Tea
590
21
Waitrose Tea
590
22
Lidl Tea
480
23
Morrisons Tea
320
24
Bewleys Tea
90
25
Cafedirect Tea
40
Few of these on here we’ve never heard of. Taste test, anyone?
While Yorkshire Tea was found to be Manchester’s and the nation’s favourite, Belfast was the only UK city where Yorkshire Tea didn’t take the top spot. Instead, it was Irish-owned Barry’s Tea that came out as their favourite – we definitely need to hold a ‘brew-off’ between the two. The Hoot, you up for it?
As for supermarket’s own-brand offerings, out of the eight options on the list, Marks and Spencer’s teabags were found to be the most popular, closely followed by Tesco and then Sainsbury’s.
Commenting on the findings, TonerGiant’s Stuart Deavall said: “With so many office workers opting for tea to get through the day, it’s no surprise that the UK has a day dedicated to the drink.
“In light of National Tea Day on Sunday, 21 April, our new data shows that Yorkshire Tea is the nation’s favourite, with over 27,000 Brits searching every month… We can expect many Brits to be celebrating in style this Sunday, no doubt with a mug of Yorkshire tea in hand”. Speaking of, anyone fancy a brew?…