In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they’re the only organ in humans that regenerates automatically and regularly, even if they haven’t been injured – and it’s from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles – including stem cells – divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: “In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
“In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing.”
“TGF-beta has two opposite roles,” Wang added.
“It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death.”
While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it’s a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it’s the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: “Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle.”
Of course, there’s still some way to go until baldness is cured – however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
“Potentially, our work could offer something to help people suffering from a variety of problems,” Wang concluded.
Trailer released for new Netflix drama series starring Michelle Keegan airing in the new year
The first trailer for a new Netflix show starring Michelle Keegan and Joanna Lumley has now been released.
In case you hadn’t heard, the highly-anticipated new crime drama show, which is titled Fool Me Once, is an adaptation of Harlan Coben’s popular novel, and is set to air on the streaming service as soon as 2024 arrives.
But now, the release of the first trailer has proved it looks brilliantly binge-worthy.
The eight-part series follows Manchester-born actress Michelle Keegan’s character, Maya Starn, who is a former special ops pilot struggling with the tragic murder of her husband, Joe, who is played by Richard Armitage.
Detective Sergeant Sami Kierce, who is portrayed by Adeel Akhtar, conducts the investigation into Joe’s death while wrestling with his own hidden truths.
Things start to get interesting though, when she observes via the nanny cam her supposedly deceased husband playing with their baby daughter in her own home.
Meanwhile, Maya’s niece and nephew embark on the journey to seek answers about their own mother’s murder which took place months ago.
But one question remains – could the two mysteries be related?
The first trailer for the show was released by Netflix at the end of last week, and it showcases a star-studded cast with the likes of Dame Joanna Lumley from Absolutely Fabulous, Adeel Akhtar from Sherwood, Emmett J Scanlan from Peaky Blinders, and Dino Fetscher from Paranoid.
The streaming service has unveiled a selection of first look images, showcasing a star-studded cast with the likes of Dame Joanna Lumley from Absolutely Fabulous, Adeel Akhtar from Sherwood, Emmett J Scanlan from Peaky Blinders, and Dino Fetscher from Paranoid.
Filming took place in Yorkshire, where production crews were spotted in the Burdock Way area near the centre of Halifax, but Michelle Keegan was also spotted filming in Manchester city centre back in May.
Fool Me Once will air on Netflix in the UK on Monday 1 January.
Featured Image – GMP
Timothée Chalamet thinks the sexiest British accent is… Hull?
Hollywood A-lister Timothée Chalamet has revealed the British accents he finds sexiest, and the results are unexpected.
The 27-year-old star of Wonka said that a Hull accent is up there as one of his favourites, along with Italian and French.
How does Timothée Chalamet even know about Hull’s existence, never mind know what the accent sounds like?
The star, who rose to astronomical fame back in 2017 with his portrayal of Elio in Call Me By Your Name, and has since starred in blockbusters such as Dune and Little Woman, revealed his favourite access on the current Wonka press tour, The Hoot reports.
Chalamet appeared on LadBible TV talking to Keegan-Michael Key, where they discuss the internet’s biggest debates.
In a segment where they debate the British accent, Chalamet goes on to reveal his top three British accents… and the answers are not what you would expect.
Firstly he admits his favourite is the Hull accent, he says: “I like the Hull accent. Hull is sexy”.
We’ve never thought of the Hull accent as particularly sexy before, but we will absolutely take it.
He then goes onto say: “I like Hull, Essex is my top three, and I like a middle-aged Yorkshire accent.”
We’re not sure the difference between a Yorkshire and a middle-aged Yorkshire accent, but what Timothée wants then Timothée will get.
In the comments, one person said: “I’m from Hull and nobody in Hull likes the Hull accent lol.”
Another joked: “suddenly i have the hull accent.”
And someone else wrote: “good day to have a hull accent.”
So thank you Timmy, we’d have to say that we wholeheartedly agree and that our accent is in fact, the sexiest of them all.
Next time we’d like to see you attempt a Yorkshire accent on the big screen, because we’re sure you’d absolutely smash it.