In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they’re the only organ in humans that regenerates automatically and regularly, even if they haven’t been injured – and it’s from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles – including stem cells – divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
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But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: “In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
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Scientists have discovered a potential cure for baldness thanks to new research / Credit: Tengyart (via Unsplash)
“In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing.”
“TGF-beta has two opposite roles,” Wang added.
“It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death.”
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While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it’s a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it’s the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: “Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle.”
Of course, there’s still some way to go until baldness is cured – however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
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“Potentially, our work could offer something to help people suffering from a variety of problems,” Wang concluded.
UK’s most popular commuter towns named and four are in Greater Manchester
Emily Sergeant
The UK’s most popular commuter towns have been named, and four of them are here in Greater Manchester.
Where are the most popular commuter towns in the UK right now?
Well, new data collated based on the number of people enquiring about available properties on Rightmove has revealed the locations where buyer demand is highest, and with Manchester being one of the largest cities in the country, of course there’s some Greater Manchester towns on the list.
Rightmove says that choosing the best commuter town requires buyers to balance a number of factors – including property prices, travel times, and local lifestyle
To narrow it down, the property platform has chosen to focus on commuter towns within a 45-minute rail journey to the target city, and with at least 20,000 people living there.
For Manchester, it’s Stockport that’s taken the title as the city’s most popular commuter town, as amazinly, it generated 70% more enquiries per listing than Manchester itself.
The UK’s most popular commuter towns have been named / Credit: James Feaver (via Unsplash) | Manchester City Council
Being just an eight-minute journey from Manchester Piccadilly, Stockport has an average property price of £308,299.
Elsewhere in Greater Manchester, the picturesque Stockport town of Marple takes second spot on the list, while the Tameside town of Stalybridge comes in third place, and Rochdale also features in the top five, alongside Warrington – which is just outside of our region’s borders, but is only a short 22-minute train journey into the city centre.
Transport options is obviously one of the most important factors in what makes a town a so-called ‘commuter town’.
Stockport benefits from around six fast trains per hour, while Stalybridge and Rochdale offer four per hour. Marple is less frequent at two per hour but still attracts strong interest, likely due to its lifestyle appeal and stunning setting on the edge of the Peak District.
Price growth has been strong across most of the Manchester commuter towns, with Stalybridge (+6.1%) and Rochdale (+5.8%) seeing notable increases year-on-year.
However, average prices for four out of the five commuter locations on the list were higher than the average Manchester property price (£261,891), suggesting that lifestyle factors were a stronger draw for Manchester’s surrounding towns.
Featured Image – Benjamin Elliott (via Unsplash)
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Noah Kahan begs fans to ‘just go to the bathroom’ ahead of Manchester shows
Daisy Jackson
Noah Kahan has had to issue a bizarre warning on concert etiquette ahead of his UK tour, after a fan apparently defecated on the floor at his show.
The Stick Season singer-songwriter, who will headline two massive gigs in Manchester this year, has begged his fans to ‘just go to the bathroom lmao’.
He’s had to speak out after videos circulated online that appeared to show human faeces beneath a chair and in the walkway at one of his US gigs.
According to witnesses at his Philadelphia show, one concert-goer relieved themselves onto the floor, then tried to kick the faeces under the seat in front.
Noah Kahan has now released a statement online that says: “If you have to poop at a show please dear god just go to the bathroom lmao.
“I’ve pooped my pants as much as the next 29 year old but you guys gotta understand there’s a venue worker out there with a 1000 yard stare after dealing with that.”
The star has since gone one step further, and addressed the poop incident on stage in Toronto.
He told fans inside the venue: “This is awkward. When you enter this building, you enter a social contract, right?
“And rule number two besides ‘don’t literally f**king kill each other’, is ‘don’t s**t on the floor’.
“So we’re gonna do some therapy type thing where we all repeat after me, okay?”
He then led the crowd to repeat the following chant: “I solemnly swear, I will not s**t my pants, and if I do, I won’t take it from my pants and put it on the floor.”
Emily Sergeant -
26th July 2022 
