In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they’re the only organ in humans that regenerates automatically and regularly, even if they haven’t been injured – and it’s from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles – including stem cells – divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
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But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: “In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
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“In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing.”
“TGF-beta has two opposite roles,” Wang added.
“It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death.”
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While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it’s a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it’s the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: “Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle.”
Of course, there’s still some way to go until baldness is cured – however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
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“Potentially, our work could offer something to help people suffering from a variety of problems,” Wang concluded.
Everton manager Sean Dyche randomly pops up in the music video for Blossoms’ new single – and he’s great
Danny Jones
Did anyone else think they’d ever see Sean Dyche make his acting debut in the role of a Northern crime boss in a silly little music video for the Blossoms?
No, us neither but that’s the bizarre alternate reality we’re living in, apparently.
Blossoms are currently working on the fifth studio album and have already released their lead single entitled, ‘To Do List (After The Break-Up)’, but now they have a new song out as well, with a rather amusing music video to go along with it and somehow Sean Dyche has found himself the star.
The Stockport band teased the curious collaboration in April, giving us just short glimpses of the Everton manager and former Burnley boss with very little explanation – all we know is that it looked funny and it was.
Dyche is still busy trying to finish the Premier League campaign as strong as possible after successfully navigating the Toffees to safety even in spite of their points deductions this season, but it sounds like keeping them up has given him enough time to moonlight as an actor.
Sending the indie five-piece on a mission to collect something of value (yes, that’s all the info we have at this point as the story is still to be continued), it looks like the Kettering-born coach has a larger role to play in whatever this narrative turns out to be.
Playing what can only be described as some kind of semi-Manc mafia figure on the hunt for a very valuable piece of art, i.e. a big giant gorilla statue – one that many Stopfordians spotted being lugged around various parts of the borough –
They also shared a little bit of BTS footage from the shoot for the music video last week. Some lovely head-bobbing and unassuming surroundings here:
As for the track itself, it’s a bit of stylistic change for the lads who’ve mastered their 80s-tinged indie formula over the past decade but it’s an absolute pop and is already stuck in our heads.
Revealing that they’ve collaborated with contemporary funk, disco and electronic icons Jungle on the track, it doesn’t take too long to hear the influences. Look forward to hearing it at Wythenshawe Park this summer.
You can watch the music video for ‘What Can I Say?’ and the ginger-goatee’d football manager extraordinaire in full character HERE.
He’s not the only footballing figure who’s made an entertainment crossover recently either.
Featured Images — Blossoms (via YouTube)/Virgin EMI
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KFC have launched their own perfume – oh, and a new burger
Danny Jones
Fast food giants KFC have launched their very own perfume in one of the weirdest marketing stunts we’ve seen in a long while.
That being said, we definitely want a bottle.
KFC‘s fried chicken-themed fragrance launches next month and is fashionably named ‘No 11 Eau de BBQ’, a nod to their newest menu item, the Ultimate BBQ Burger, which we also want in our possession as soon as humanly possible.
The franchise’s new signature scent launches in just a week’s time and, yes, you can genuinely buy it along with the new burger for a limited time only.
The UK-only release actually sold out when it came to pre-orders but Brits will be able to get their hands on another batch when the second lot drops on 7 May.
Promising a charcoal and smoky wood-scented aroma that immediately transports you to your mate’s back garden as he turns cheap burger patties into overly blackened dry pucks of meat that you definitely would’ve cooked better if you were in charge, the stunt is also helping raise money for non-profits.
Available in 100ml bottles and for just £11, 100% of the proceeds of every sale will go towards the KFC Foundation, which supports grassroots organisations empowering young people to unleash their potential and build a positive future in local communities across the country.
As for the burger that inspired it, the special edition menu item is a nod to BBQ season gradually approaching and they’ve even made a nod to our famously reliable British weather and its attempts to derail the art of outdoor grilling in a new advert.
KFC perfume and a new burger? Christmas has come well early this year.
The Ultimate BBQ Burger has already launched and will be on the menu until 9 June, priced at £6.49 or £9.99 for a box meal which comes with the burger, a regular mini fillet, regular fries, BBQ sauce and a drink.
And don’t worry, it’ll be available on delivery too — we know we’ve had problems with that when it comes to specials in the past.
As KFC’s No 11 Eau de BBQ perfume, you can wait in the online queue like everyone else HERE and let’s just say you’ll be fighting us and plenty of other Mancs for every last drop.