A clinical trials patient in Manchester is celebrating a new lease of life after having had “a remarkable response” to a new specific gene-targeting treatment that controls how cancer grows.
49-year-old Terri Hurdman, from Bromsgrove in Worcestershire, found out she had advanced bowel cancer on Valentine’s Day two years ago, and didn’t even think she’d make it past Christmas 2021 after finding herself left completely exhausted and out of breath from simple tasks such as climbing the stairs, walking a short distance, or even talking on the phone due to her cancer.
But within hours of trialling a new drug at The Christie NHS Foundation Trust, she was climbing stairs with no effort.
After three months, scans showed her tumours had halved in size.
Terri – who has three children and six grandchildren – was a previously fit and healthy factory worker used to doing manual work for a firm producing medical supplies, and had no symptoms until she got stomach ache and thought it might be IBS – but after having been referred by her GP to Kidderminster hospital, she was diagnosed with stage 4 colorectal cancer, which had spread to her lungs, and started chemotherapy a month later.
After three types of chemotherapy didn’t work, she was told she had no other options and was taken off the drugs.
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By August 2021, Terri had become very ill, had lost a stone and a half in weight, and was becoming weaker, so she was forced to use a wheelchair to get out and about, but luckily, her consultant at Kidderminster hospital knew The Christie in Manchester was running early phase clinical trials which used targeted therapies – a type of cancer treatment that targets the genes and proteins that control how cancer cells grow and spread – and referred her to see if the trial would be suitable.
Terri is taking part in a new experimental drug trial at The Christie in Manchester / Credit: The Christie NHS Foundation Trust
Terri’s DNA had already been analysed as part of standard NHS testing, and it was found she had a mutation in the KRAS gene of her cancer.
Fortunately, the new international clinical trial was designed specifically for people with the gene mutation that Terri has, so she passed the screening and was recruited onto the trial, and immediately after taking the first dose of the tablets last October, her condition “improved significantly”, specialists at The Christie said.
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So much so, Terri was able to walk up some stairs without getting out of breath for the first time in months.
“It’s like a miracle. It really is a wonder drug as within days, I didn’t need to use the wheelchair at all, and I didn’t get out of breath climbing stairs, which would have previously led to a coughing fit,” Terri explained.
“That day, I spoke to my sister on the phone for an hour, something that would have wiped me out before, and my appetite came back, which made me look so much healthier, and the colour returned to my cheeks.
“I didn’t think I’d make it to Christmas, but now I’m looking forward to celebrating my 50th birthday in July.
Microdot exhibit for BRITs 2026: the artwork of Oasis, Verve and more up in Manchester Piccadilly
Danny Jones
If you’ve passed through Manchester Piccadilly of late, you might have noticed two things: one, it’s really quiet, and two, there’s loads of cool Britpop merch and memorabilia on display, including original Oasis, The Verve, Inspiral Carpets art and more – all courtesy of Microdot.
Set up as part of the city’s own BRITs celebrations, along with a raft of other nationwide festivities, as the annual music award ceremony prepares to make its Manc debut at the Co-op Live this month, the showcase features special edition frames and more, all pride of place in the middle of the train station.
This collection, simply entitled ‘A Microdot Design’, is all done by the legendary Brian Cannon, the graphic designer and art director behind so much recognisable visual material within the genre.
We recently had the honour of speaking to the man himself in person ahead of Piccadilly’s temporary closure; you can see our interview with him right here:
The Wigan-born artist and visionary didn’t just make promotional materials for some of the biggest bands in the 1990s; he’s responsible for what has gone on to become some of the most familiar iconography in British music history.
With this pop-up exhibit available for a limited time only, we strongly urge you to go along and, for once, take your time rather than rushing around the station as you peruse the boards placed right near the main entrance.
Charting his work from circa 1990 up until now, it’s crazy to see just how many of Brian and Microdot’s fingerprints are all over so many different bands and artists.
From native names like Oasis, The Verve and the Inspirals, as mentioned, as well as the likes of Cast, Super Furry Animals, Suede and Ash, plus so many more, this guy has been nothing short of prolific over the past few decades.
Audio North took a little tour of the King Street South unit last year in the lead-up to Oasis Live ’25 reunion world tour, and we felt like kids in a Britpop sweetshop.
While this site has sadly since closed, shutting up shop back in July, Brian’s mini, modest, but nevertheless magic Microdot Boutique up in the Lake District is still standing.
Located in the popular North West town and tourist attraction, Kendal, it’s worth a trip there to see more of his portfolio alone.
Currently on display at Manchester Piccadilly ahead of the full 2026 BRITs Week and shindig at Co-op Live, it’s one of the best completely free things you can do in town at the moment – but the exhibition finishes on Sunday, 1 March, so make sure you don’t miss it.
Speaking of the BRIT Awards, if you’re wondering what else is on as 0161 gets ready welcome them for their two-year stint (at least), look no further…
Two brothers from Oldham are beating out the likes of Taylor Swift in the iTunes charts
Danny Jones
A pair of brothers from Oldham who simply go by Two Connors are now holding on to the top spot in one of the biggest iTunes charts, and they’re beating the likes of Taylor Swift, Bruno Mars, Bad Bunny and many more.
Stuff your global music stars, we’ll back a duo from Greater Manchester all day long.
Danny and Callum Connor, a couple of blokes from Oldham in their mid-30s, are currently number one in the iTunes singles charts with their latest song, ‘Familiar Faces’, but this isn’t the first time they’ve gone big with a release online.
Carving out their own little corner not only in the old Lancashire borough but a small pocket in the UK’s wider grime, drill, rap and hip-hop scene, they’ve only gotten bigger over the last 18 months or so.
After releasing their first two tracks back in 2024, Callum and Danny have been on a very gradual rise, but they quickly gained a cult local following in and around Oldham.
Writing about life and around the area, with high personal and anecdotal lyrics that feel like niche references and in-jokes specifically for‘Roughyed’ residents – it’s not just music by them but FOR them.
In addition to recording their own unique cover of ‘Bad Habits’ by Ed Sheeran, they also went fairly viral for releasing a music video featuring crowds of local children.
Putting their own chant-based chorus slant on ‘Hi Ho, Hi Ho, “It’s off to Work We Go”‘, written by Mitch Miller and The Sandpipers (yes, as in the main theme from Snow White and the Seven Dwarfs), it was a fairly radio-friendly tune that was easy for kids and more to sing along with.
With various other natives getting involved in the music video, joining them on the town centre streets and lip-syncing the lyrics, it was circulated online all over Britain and beyond.
You can watch it in full down below.
Fast forward to February 2026, and not only have they grown their following across the region, but even further afield now, as it turns out; currently sitting ahead of ‘Opalite’ from worldwide smash-hit album, The Life of a Showgirl, who needs big label backing, eh?
Bringing smiles to even more Greater Mancs by quite literally shining the spotlight on ‘Familiar Faces’ and punters from nearby pubs such as The Up Stepps Inn and former nightclub Sruples, it is a real tribute to their homeland.
Only time will tell how long they’ll cling to that iTunes top spot, but with nearly 73,000 monthly listeners on Spotify and counting, they might be one of the biggest music names to come out of OL in some time.
In other big news over in Oldham, on the sporting side of things, RLFC are staring down yet more uncertainty, with local hero Bill Quinn also wrapping up his time at the club.
Emily Sergeant -
30th March 2022 
