A clinical trials patient in Manchester is celebrating a new lease of life after having had “a remarkable response” to a new specific gene-targeting treatment that controls how cancer grows.
49-year-old Terri Hurdman, from Bromsgrove in Worcestershire, found out she had advanced bowel cancer on Valentine’s Day two years ago, and didn’t even think she’d make it past Christmas 2021 after finding herself left completely exhausted and out of breath from simple tasks such as climbing the stairs, walking a short distance, or even talking on the phone due to her cancer.
But within hours of trialling a new drug at The Christie NHS Foundation Trust, she was climbing stairs with no effort.
After three months, scans showed her tumours had halved in size.
Terri – who has three children and six grandchildren – was a previously fit and healthy factory worker used to doing manual work for a firm producing medical supplies, and had no symptoms until she got stomach ache and thought it might be IBS – but after having been referred by her GP to Kidderminster hospital, she was diagnosed with stage 4 colorectal cancer, which had spread to her lungs, and started chemotherapy a month later.
After three types of chemotherapy didn’t work, she was told she had no other options and was taken off the drugs.
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By August 2021, Terri had become very ill, had lost a stone and a half in weight, and was becoming weaker, so she was forced to use a wheelchair to get out and about, but luckily, her consultant at Kidderminster hospital knew The Christie in Manchester was running early phase clinical trials which used targeted therapies – a type of cancer treatment that targets the genes and proteins that control how cancer cells grow and spread – and referred her to see if the trial would be suitable.
Terri is taking part in a new experimental drug trial at The Christie in Manchester / Credit: The Christie NHS Foundation Trust
Terri’s DNA had already been analysed as part of standard NHS testing, and it was found she had a mutation in the KRAS gene of her cancer.
Fortunately, the new international clinical trial was designed specifically for people with the gene mutation that Terri has, so she passed the screening and was recruited onto the trial, and immediately after taking the first dose of the tablets last October, her condition “improved significantly”, specialists at The Christie said.
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So much so, Terri was able to walk up some stairs without getting out of breath for the first time in months.
“It’s like a miracle. It really is a wonder drug as within days, I didn’t need to use the wheelchair at all, and I didn’t get out of breath climbing stairs, which would have previously led to a coughing fit,” Terri explained.
“That day, I spoke to my sister on the phone for an hour, something that would have wiped me out before, and my appetite came back, which made me look so much healthier, and the colour returned to my cheeks.
“I didn’t think I’d make it to Christmas, but now I’m looking forward to celebrating my 50th birthday in July.
Luxury Manchester gym Blok confirms permanent closure after weeks of uncertainty
Daisy Jackson
Blok Manchester has announced its permanent closure, weeks after the doors to the premium fitness facility mysteriously closed.
Around a fortnight ago, members began to arrive to their classes to find the gym on Ducie Street locked up and a forfeiture notice on the door – but at the time, Blok said that it was fighting to reopen.
Sadly, in an email sent to members today, its founder has confirmed that the studio is now permanently closed.
Blok – which has several very successful sites down in London – said that its relationship with its landlord has ‘broken down to a point where trust has been lost’.
The gym wrote that it’s been left with ‘no workable way forward’.
They said: “BLOK Manchester was a space built by our loyal and dedicated community. Whether you joined us for one class or one hundred, we are deeply grateful. You helped create something genuinely special in an incredible city.”
In the immediate future, they said they’ll be supporting the team of fantastic trainers who worked here, as well as looking after members.
Members will be contacted within a few hours with options and refunds owed.
Blok Manchester has announced its permanent closure. Credit: The Manc Group
CEO and founder Ed Stanbury said: “While this marks the end of a chapter, we don’t see it as the end of our story in Manchester. We’re already speaking with developers about potential future sites and remain committed to returning to the city when the time is right.
“Thank you for being part of our story so far. Let’s shape the future of wellness. The mission continues.”
Commenting on Blok’s Instagram post – its first in almost a fortnight – people have been sharing their sadness at the closure of its Manchester site.
One person wrote: “beautiful space, beautiful staff and beautiful community.”
Another said: “Sending love to all the instructors !! :(((( gutted”
Someone else commented: “THE BEST CLASSES. I’m gutted.”
‘The average cost of a pint’ in the UK by region, according to the latest data
Danny Jones
Does it feel like pints keep getting more and more expensive almost every week at this point? Yes. Yes, it does, and while you can’t expect a city as big as Manchester to be one of the cheapest places to get one in the UK, we do often wonder how it compares to other parts of the country.
Well, as it happens, someone has recently crunched the numbers for us across the nation, breaking down which regions pay the most and the least for their pints.
The data has been examined by business management consultancy firm, CGA Strategy, using artificial intelligence and information from the latest Retail Price Index figures to find out what the ‘average cost of a pint’ is down south, up North and everywhere in between.
While the latest statistics provided by the group aren’t granular enough to educate us on Greater Manchester’s pint game exactly, we can show you how our particular geographic region is looking on the leaderboard at the moment.
That’s right, we Mancunians and the rest of the North West are technically joint mid-table when it comes to the lowest average cost of a pint, sharing the places from 3rd to 8th – according to CGA, anyway.
Powered by consumer intelligence company, NIQ (NielsenIQ) – who also use AI and the latest technology to deliver their insights – we can accept it might seem like it’s been a while since you’ve paid that little for a pint, especially in the city centre, but these are the stats they have published.
Don’t shoot the messenger, as they say; unless, of course, they’re trying to rob you blind for a bev. Fortunately, we’ve turned bargain hunting at Manchester bars into a sport at this point.
We might not boast the lowest ‘average’ pint cost in the UK, but we still have some bloody good places to keep drinking affordable.
London tops the charts (pretends to be shocked)
While some of you may have scratched your eyes at the supposed average pint prices here in the North West, it won’t surprise any of you to see that London leads the way when it came to the most expensive pint when it came to average cost in the UK.
To be honest, £5.44 doesn’t just sound cheap but virtually unheard of these days.
CGA has it that the average cost of a beer in the British capital is actually down 15p from its price last September, but as we all know, paying upwards of £7 for a pint down that end of the country is pretty much par for the course the closer you get to London.
Yet more reason you can be glad you live around here, eh? And in case you thought you were leaving this article with very little, think again…
Emily Sergeant -
30th March 2022 
