A clinical trials patient in Manchester is celebrating a new lease of life after having had “a remarkable response” to a new specific gene-targeting treatment that controls how cancer grows.
49-year-old Terri Hurdman, from Bromsgrove in Worcestershire, found out she had advanced bowel cancer on Valentine’s Day two years ago, and didn’t even think she’d make it past Christmas 2021 after finding herself left completely exhausted and out of breath from simple tasks such as climbing the stairs, walking a short distance, or even talking on the phone due to her cancer.
But within hours of trialling a new drug at The Christie NHS Foundation Trust, she was climbing stairs with no effort.
After three months, scans showed her tumours had halved in size.
Terri – who has three children and six grandchildren – was a previously fit and healthy factory worker used to doing manual work for a firm producing medical supplies, and had no symptoms until she got stomach ache and thought it might be IBS – but after having been referred by her GP to Kidderminster hospital, she was diagnosed with stage 4 colorectal cancer, which had spread to her lungs, and started chemotherapy a month later.
After three types of chemotherapy didn’t work, she was told she had no other options and was taken off the drugs.
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By August 2021, Terri had become very ill, had lost a stone and a half in weight, and was becoming weaker, so she was forced to use a wheelchair to get out and about, but luckily, her consultant at Kidderminster hospital knew The Christie in Manchester was running early phase clinical trials which used targeted therapies – a type of cancer treatment that targets the genes and proteins that control how cancer cells grow and spread – and referred her to see if the trial would be suitable.
Terri is taking part in a new experimental drug trial at The Christie in Manchester / Credit: The Christie NHS Foundation Trust
Terri’s DNA had already been analysed as part of standard NHS testing, and it was found she had a mutation in the KRAS gene of her cancer.
Fortunately, the new international clinical trial was designed specifically for people with the gene mutation that Terri has, so she passed the screening and was recruited onto the trial, and immediately after taking the first dose of the tablets last October, her condition “improved significantly”, specialists at The Christie said.
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So much so, Terri was able to walk up some stairs without getting out of breath for the first time in months.
“It’s like a miracle. It really is a wonder drug as within days, I didn’t need to use the wheelchair at all, and I didn’t get out of breath climbing stairs, which would have previously led to a coughing fit,” Terri explained.
“That day, I spoke to my sister on the phone for an hour, something that would have wiped me out before, and my appetite came back, which made me look so much healthier, and the colour returned to my cheeks.
“I didn’t think I’d make it to Christmas, but now I’m looking forward to celebrating my 50th birthday in July.
You can get FREE food and more at Tesco Christmas Markets across Greater Manchester
Thomas Melia
Tesco Christmas Markets are back and heading to even more Greater Manchester locations where you can try lots of festive items all for FREE.
If you missed it last year, then don’t worry, as Tesco has brought back its much-loved Christmas Markets and the stalls are visiting more locations across the UK than ever before.
We’ve got you covered with all the dates and locations these freebie-filled Christmas Markets are visiting to make sure you don’t catch a case of festive FOMO.
Tesco Christmas Markets will be filled with all your favourite brands you usually fill up your trolley with from the likes of Costa, McCain, Celebrations and more.
And of course, it wouldn’t be a Tesco-led celebration without its own Finest range making an appearance across select Greater Manchester locations.
Expect to sample Tesco Finest Scallop and King Prawn Toast, Tesco Finest Stratford Blue with Fig Conserve and sweet treat staple, Tesco Finest Brandy Butter Mince Pies.
The best-loved brands mentioned before will be offering samples like smooth and creamy cups of Chocomel, or caramel-infused Nutcracker Spectacular drinks thanks to coffee shop chain Costa too.
In terms of food, McCain are letting you crunch down on its latest crisp range Vibes, Celebrations is treating you to its chocolate collection and biscuit varities from Bahlsen.
Tesco Christmas Markets are visiting major Greater Manchester locations giving out lots of FREE food / Credit: Press Shots (via Supplied)
Feeling merry and bright? Alcoholic drink brands 1664 is bringing out its blue bottles, Three Barrels for its XO and VSOP brandies as well as the coffee-infused liquer Drambuie.
If you’re after something to warm up your winter’s day, Costa is also letting you try some of its Home-made Barista style coffees and coffee pod masterminds Tassimo are offering samples of its Cadbury, L’Or, Kenco ranges and more.
Finally, if that wasn’t enough for you, why not clear your palette with a Christmas creation courtesy of teapigs and its caffeine-free peppermint leaves, yum.
Here’s all the important dates and locations for Tesco Christmas Markets 2025 schedule for Greater Manchester and wider regions:
Fri 14 November – Glossop Superstore, SK13 8HB
Sat 15 November – Hattersley Extra in Hyde, SK14 3AU
Sun 16 November – Failsworth Extra in Manchester, M35 0EJ
Mon 17 November – Manchester Gorton Extra, M18 8LD
Tue 18 November – Stockport Extra, SK1 2BT
Wed 19 November – Burnage Superstore in Manchester, M19 1TF
Thu 20 November – Prestwich Superstore in Manchester, M25 3TG
Fri 21 November – Bolton Horwich Extra, BL6 6JS
Sun 23 November – Chorley Extra, PR7 1NW
Mon 24 November – Leyland Extra, PR25 2FN
Sun 30 November – Prescot Extra, L34 5NQ
Mon 1 December – St Helens Extra, WA9 3AL
Tue 2 December – Widnes Extra, WA8 7YT
Wed 3 December – Warrington Extra, WA2 7NE
Mon 8 December – Accrington Extra, BB5 1LN
Fri 12 December – Macclesfield Hibel Road Superstore, SK10 2AB
To view a full list of all the Tesco Christmas Markets locations across the UK and browse all the brands that are taking part you can find everything HERE.
£50k reward for information about Baby Ava, whose remains were found in a Salford field
Daisy Jackson
Police are offering a £50,000 reward in a bid for information about Baby Ava, the newborn whose remains were found in a field in Salford one year ago.
One year on from the discovery of the baby girl’s remains in Little Hulton, police are still desperately trying to find out the baby girl’s identity and how she came to be in Ashtons Field.
A reward of £50,000 has now been secured from the Greater Manchester Combined Authority, with an appeal for her parents to come forward, or anyone with information that helps identify Ava or her parents.
New developments since the discovery of the baby’s remains on 20 November 2024 have included recovering a piece of fabric that was a distinctive pair of ladies’ underwear.
The size large underwear are patterned with what police believe are cartoon donkeys – but this has given no viable lead.
GMP’s lead investigator, Detective Inspector Louise Kelly from GMP’s Major Incident Team, said: “Since Ava was discovered a year ago today, we have worked tirelessly to understand how she came to be in Ashtons Field deceased and get justice for her.
“Last month, we were able to share that a piece of fabric recovered with Ava was a distinctive pair of ladies’ size large underwear with what believe are cartoon donkeys on. Unfortunately, despite the unique nature of this piece of clothing, we have had no new viable leads.
A ‘distinctive’ pair of ladies’ underwear discovered with Baby Ava. Credit: GMP
“We have had around 20 experts across various fields supporting our enquiries, followed up on over 200 pieces of information and distributed 1000 leaflets to local communities.
“Those residing in the surrounding area of where Ava was located should expect to see a greater police presence in the area around this anniversary, and may receive a knock on the door, as we continue to relentlessly pursue all possible avenues which could lead us to finding out what happened to her.”
DI Kelly continued yesterday, the one-year anniversary of the discovery of Baby Ava: “Today’s date will be a significant one for Ava’s parents and those who may have known her, and we have not lost hope in understanding the full circumstances of Ava’s death.
“To Ava’s parents, if they see this, we are here ready to speak to you and support you.”
Kate Green, Deputy Mayor of Greater Manchester for Safer and Stronger Communities, said: “Our thoughts remain with Baby Ava and those affected by this tragic case.
“We are committed to supporting GMP in their efforts to find answers and bring closure.
“This reward reflects our determination to encourage anyone with information to come forward and assist with the police with their investigation.”
Anyone with information is asked to contact police on 101 quoting log 1319 of 20/11/24. Information can also be shared via the Major Incident Public Portal here.