A clinical trials patient in Manchester is celebrating a new lease of life after having had “a remarkable response” to a new specific gene-targeting treatment that controls how cancer grows.
49-year-old Terri Hurdman, from Bromsgrove in Worcestershire, found out she had advanced bowel cancer on Valentine’s Day two years ago, and didn’t even think she’d make it past Christmas 2021 after finding herself left completely exhausted and out of breath from simple tasks such as climbing the stairs, walking a short distance, or even talking on the phone due to her cancer.
But within hours of trialling a new drug at The Christie NHS Foundation Trust, she was climbing stairs with no effort.
After three months, scans showed her tumours had halved in size.
Terri – who has three children and six grandchildren – was a previously fit and healthy factory worker used to doing manual work for a firm producing medical supplies, and had no symptoms until she got stomach ache and thought it might be IBS – but after having been referred by her GP to Kidderminster hospital, she was diagnosed with stage 4 colorectal cancer, which had spread to her lungs, and started chemotherapy a month later.
After three types of chemotherapy didn’t work, she was told she had no other options and was taken off the drugs.
By August 2021, Terri had become very ill, had lost a stone and a half in weight, and was becoming weaker, so she was forced to use a wheelchair to get out and about, but luckily, her consultant at Kidderminster hospital knew The Christie in Manchester was running early phase clinical trials which used targeted therapies – a type of cancer treatment that targets the genes and proteins that control how cancer cells grow and spread – and referred her to see if the trial would be suitable.
Terri is taking part in a new experimental drug trial at The Christie in Manchester / Credit: The Christie NHS Foundation Trust
Terri’s DNA had already been analysed as part of standard NHS testing, and it was found she had a mutation in the KRAS gene of her cancer.
Fortunately, the new international clinical trial was designed specifically for people with the gene mutation that Terri has, so she passed the screening and was recruited onto the trial, and immediately after taking the first dose of the tablets last October, her condition “improved significantly”, specialists at The Christie said.
So much so, Terri was able to walk up some stairs without getting out of breath for the first time in months.
“It’s like a miracle. It really is a wonder drug as within days, I didn’t need to use the wheelchair at all, and I didn’t get out of breath climbing stairs, which would have previously led to a coughing fit,” Terri explained.
“That day, I spoke to my sister on the phone for an hour, something that would have wiped me out before, and my appetite came back, which made me look so much healthier, and the colour returned to my cheeks.
“I didn’t think I’d make it to Christmas, but now I’m looking forward to celebrating my 50th birthday in July.
Kalvin Phillips is reportedly set to be reintegrated into the Manchester City squad
Danny Jones
Long-exiled Manchester City player Kalvin Phillips is reportedly on the verge of being reintegrated into Pep Guardiola’s squad this season.
The ex-Leeds United star, who signed for the Blues back in 2022, has still only made just 16 appearances for the club, but could now be eyeing up a potential renaissance.
Man City have made plenty of signings this year, but with a number of outgoings and several injuries in key positions, it looks like there could be an avenue for the one-time England international to fight his way back into the team.
As per Telegraph Sport‘s Mike McGrath, Kalvin Phillips is set to be reintroduced to City’s 25-man Premier League selection; the question is, can he make it into a first-team XI?
🚨 EXCLUSIVE: Kalvin Phillips has chance to resurrect career at the Etihad Stadium after failed loan spells with Ipswich and West Ham
According to McGrath, Phillips will be “given a chance to resurrect his career at the Etihad Stadium” with the meat and potatoes of the 2025/26 campaign still yet to get properly underway.
Now 29, the Yorkshireman is well and truly within the crucial ‘prime’ years as an athlete, and after such an extended period on the sidelines, he’ll be more motivated than anyone to get his career back on track.
The central defensive midfielder – who was formerly considered a key cog in the middle of the park for Leeds – has spent two loan spells away from the Etihad, but neither really worked out for the undeniably talented footballer.
Having joined West Ham for the latter portion of the 23/24 term and spending the last 12 months on loan at struggling Ipswich Town, his time at both clubs was pretty forgettable, punctuated by little more than a couple of unfortunate red cards and more time on the bench.
Speaking to Sky Sports fairly recently, he confessed that the last couple of years have been very difficult and was visibly emotional discussing his struggles since moving to Man City.
It’s also worth noting that Guardiola himself has admitted to feeling “so bad” for Kalvin Phillips’ situation – perhaps why he now looks like he could be given a second chance.
CDM-wise, Rodri and Nico González are considered the go-to options, but Stockport-born Rico Lewis and Mateo Kovačić have also been used in the role.
Once again, although Man City face somewhat of an injury crisis ahead of the Manchester derby this weekend, any prolonged absences could at least see an opportunity arise for the forgotten man.
What do you make of Kalvin Phillips’ chances of being restored to the Manchester City squad and maybe even putting himself back into national team contention ahead of the World Cup?
Featured Images — Sky Sports (screenshot via YouTube)/pantkiewicz (via Flickr)
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Brand new venue confirmed as the host of The Manchester 24 Hour Run Against Homelessness
Danny Jones
The magnificent Manchester 24 Hour Run Against Homelessness is back this year, and with the 2025 event fast approaching, they have announced arguably their biggest host venue yet, setting up in camp in a brand new food and drink hall.
Having housed the incredible charity gathering from Freight Island last year, it was always going to take some beating this time around, but somehow they’ve managed to.
The annual relay run in aid of Greater Manchester’s homeless community will be taking place at none other than the city centre’s recently unveiled House of Social, with the building’s wider student living quarters serving as the perfect fit for the initiative first thought up by university friends back in 2018.
Announced this week, House of Social will be teaming up with the wider First Street neighbourhood to look after the hordes of incredible runners this year.
Jamie Hills, Development Director at Ask Real Estate – who operate the ever-growing First St complex – said of volunteering as this year’s hosts: “First Street is thrilled to welcome and fuel the incredible runners of The Manchester 24 Hour Run Against Homelessness.
“As the city’s hotspot for community events and culture, we’re proud to be a place where community thrives, so we’re incredibly excited to support this important initiative. With our fantastic on-site amenities like House of Social, we’re ready to keep those participating powered up and going strong!”
As for co-founder Tom Lewis, speaking to The Manc, he said: “We’re excited to return for our 7th edition, with Manchester being our flagship event.
“Through being hosted at House of Social in First Street, we’re hoping to make this year’s edition the best and biggest yet, aiming to raise £50,000 for the Greater Manchester Mayor’s Charity Scheme, ‘A Bed Every Night’.
“We’d love to see you all at the event, plus bring your friends and workplace to. There are paces for everyone, including walking laps.”
In November 2024, not only did the fundraising phenomenon mark its first-ever expansion with an inaugural event in Birmingham, but it also surpassed £50,000 here in Manchester alone, and is now set to make debuts in a trio of new cities.
Tom went on to add: “I couldn’t be more proud of what we’ve managed to accomplish as a team with starting up three more events across the country this year and expanding Manchester to a scale we couldn’t have dreamed of when we started out seven years ago.”
We here at The Manc Group have been helping The MCR 24 Run Against Homelessness for several years now, and have put in plenty of those 5k laps between ourselves, so you can bank on us being there to put in some more hard yards this November.
Even better still, we’ve already roped in our friends over at The Hoot to help out with the maiden 24 Hour Run Against Homelessness in Leeds, and we hope to see lots more of you chipping in across the North and beyond.
Here’s to helping rough sleepers find beds and get back on their feet all over the country.
The @mcr24hourrun is expanding in 2025 and is heading to Leeds for the first time. 🏃♂️
And they're not the only city making their debut this year either… 👊
Emily Sergeant -
30th March 2022 
