A clinical trials patient in Manchester is celebrating a new lease of life after having had “a remarkable response” to a new specific gene-targeting treatment that controls how cancer grows.
49-year-old Terri Hurdman, from Bromsgrove in Worcestershire, found out she had advanced bowel cancer on Valentine’s Day two years ago, and didn’t even think she’d make it past Christmas 2021 after finding herself left completely exhausted and out of breath from simple tasks such as climbing the stairs, walking a short distance, or even talking on the phone due to her cancer.
But within hours of trialling a new drug at The Christie NHS Foundation Trust, she was climbing stairs with no effort.
After three months, scans showed her tumours had halved in size.
Terri – who has three children and six grandchildren – was a previously fit and healthy factory worker used to doing manual work for a firm producing medical supplies, and had no symptoms until she got stomach ache and thought it might be IBS – but after having been referred by her GP to Kidderminster hospital, she was diagnosed with stage 4 colorectal cancer, which had spread to her lungs, and started chemotherapy a month later.
After three types of chemotherapy didn’t work, she was told she had no other options and was taken off the drugs.
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By August 2021, Terri had become very ill, had lost a stone and a half in weight, and was becoming weaker, so she was forced to use a wheelchair to get out and about, but luckily, her consultant at Kidderminster hospital knew The Christie in Manchester was running early phase clinical trials which used targeted therapies – a type of cancer treatment that targets the genes and proteins that control how cancer cells grow and spread – and referred her to see if the trial would be suitable.
Terri is taking part in a new experimental drug trial at The Christie in Manchester / Credit: The Christie NHS Foundation Trust
Terri’s DNA had already been analysed as part of standard NHS testing, and it was found she had a mutation in the KRAS gene of her cancer.
Fortunately, the new international clinical trial was designed specifically for people with the gene mutation that Terri has, so she passed the screening and was recruited onto the trial, and immediately after taking the first dose of the tablets last October, her condition “improved significantly”, specialists at The Christie said.
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So much so, Terri was able to walk up some stairs without getting out of breath for the first time in months.
“It’s like a miracle. It really is a wonder drug as within days, I didn’t need to use the wheelchair at all, and I didn’t get out of breath climbing stairs, which would have previously led to a coughing fit,” Terri explained.
“That day, I spoke to my sister on the phone for an hour, something that would have wiped me out before, and my appetite came back, which made me look so much healthier, and the colour returned to my cheeks.
“I didn’t think I’d make it to Christmas, but now I’m looking forward to celebrating my 50th birthday in July.
Work begins on new £500m ‘culture hub’ with a cinema and performance spaces in Manchester
Emily Sergeant
Work is finally beginning on a new £500 million culture hub in Manchester.
The first phase of plans to transform Wythenshawe Civic has entered an exciting new chapter, with Manchester City Council and placemaker Muse officially commencing construction of the new Culture Hub – which is tipped to provide a ‘major boost’ for budding artists, and creative groups and organisations in the area.
The hub is set to include space for food and drink on the ground floor, while the first floor is home to a mix of artist studio spaces and flexible areas for workshops, exhibitions, classes, and community events.
Locals can also expect a brand-new 40-seater cinema, which has been included following feedback given during a public consultation, and 200-seater performance space for a diverse range of performances.
Everything from dance and drama, to music and modern art will fill the performance spaces once the hub opens.
Expected to be completed in 2027, the Culture Hub sits within the first phase of a wider plan to ‘refresh’ Wythenshawe Civic, and will come to life thanks to £20 million of funding from the UK Government and a further £11.9 million from the Council.
What Wythenshawe Civic Centre looks like currently, before being transformed / Credit: Wikipedia Commons
“Listening to local people over the last year and more, we know that Wythenshawe residents want more from their town centre – more things to do, opportunities to spend time in Civic and night time attractions that give the area a lift and attract visitors,” explained Cllr Bev Craig, who is the leader of Manchester City Council.
“This is the drive behind the Culture Hub – a place for local people with an interest in the arts to take part in creative activities, see a show, or enjoy the cinema space, right in the heart of their community.
“This is another exciting chapter in the transformation of Wythenshawe town centre.”
Joe Stockton, Development Director at Muse, called the construction of the new Culture Hub an ‘exciting moment’ for Wythenshawe.
He added: “Our aim is to create a space for the town’s talented artists and creatives to come together and give them the facilities and the space they’ve asked for, to put on amazing shows, live performances, and workshops.
“It’s all part of the wider plan to create opportunities for residents, new homes and jobs, as well as a thriving high street for people to spend time in.”
Featured Image – Manchester City Council
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Police launch investigation after man found ‘injured and unresponsive’ in Manchester road
Emily Sergeant
A police investigation has been launched after a man was found ‘injured and unresponsive’ in the middle of a road in Manchester.
Greater Manchester Police (GMP) was called out Plymouth Grove, in the Longsight area of Manchester, at around 9pm this past Friday (30 January), and when they arrived at the scene, found a 61-year-old man lying in the road.
After being found ‘unresponsive’, the man was immediately taken to hospital, where he is currently being treated for head injuries.
At this time, it is currently unknown how than man came to be in the road.
With so many questions left to answer, and a police investigation now underway being led by GMP’s Serious Collision Investigation Unit, officers are now urgently appealing to the public for witnesses and information.
“We have an open mind as we investigate how this man became to be injured,” explained PC Megan Stockton in the appeal. “However, there is the possibility he was struck by a vehicle.
“We are appealing for anyone who may have been in the area at the time, particularly anybody who may have dashcam footage taken in the area on Friday night.”
Can you help? If you have any information that could assist GMP’s investigation, then please contact police on 0161 856 4741, quoting incident number 3421 of 30/01/26, or by calling 101 or using the LiveChat at www.gmp.police.uk.
Alternatively, you can contact Crimestoppers, anonymously, on 0800 555 111.
Emily Sergeant -
30th March 2022 
