Parkinson’s Disease could be diagnosed with skin swab tests, Manchester scientists discover
Scientists at the University of Manchester have made a “game-changing” breakthrough by discovering that Parkinson’s Disease could be diagnosed using a simple skin swab test.
Scientists at the University of Manchester have made a “game-changing” breakthrough by discovering that Parkinson’s Disease could be diagnosed using a simple skin swab test.
Results published this week showed that Parkinson’s sufferers may produce higher amounts of a substance called sebum – which coats and protects the skin.
A swab test can detect these compounds; and may help researchers determine whether new treatments are able to slow, stop or reverse the progression of the disease.
The study was funded following the case of Joy Milne – a woman who stunned scientists by revealing she could detect Parkinson’s disease through smell.
Joy told researchers that she could smell a “musky” odour on her husband Les – who was diagnosed with Parkinson’s years later.
Professor Perdita Barran, Professor of Mass Spectrometry at UoM, said the results were “an extremely encouraging step” towards tests that could be used to help diagnose and monitor Parkinson’s.
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“Not only is the test quick, simple and painless but it should also be extremely cost-effective because it uses existing technology that is already widely available,” said the professor.
“We are now looking to take our findings forwards to refine the test to improve accuracy even further and to take steps towards making this a test that can be used in the NHS and to develop more precise diagnostics and better treatment for this debilitating condition.”
Parkinson’s can be difficult to diagnose / Image: Pixabay
Parkinson’s UK analysis suggests that 1 in 37 people will be diagnosed with Parkinson’s in their lifetime.
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The onset of the disease – which sees the sufferer develop a range of physical symptoms such as tremors and stiff, slow movements – is often gradual; worsening over a period of months and years.
The condition can be difficult to diagnose, too.
In a recent survey of more than 2,000 people with Parkinson’s, more than a quarter revealed they were initially misdiagnosed with a different condition.
It took four years for Daxa Kalayci, 56, to be given an accurate diagnosis of Parkinson’s.
“Despite my diagnosis eventually being confirmed by a DaTscan, a quick and simple diagnostic test for Parkinson’s would have given me the chance to start my treatment earlier and enjoy life a lot more,” said Daxa.
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“But instead, I lost so many years not being able to pursue a career as a paramedic or go back to nursing.
“This test could be a game-changer for people living with Parkinson’s and searching for answers like I was.”
Professor David Dexter, Associate Director of Research at Parkinson’s UK said that two more people in the UK are diagnosed with Parkinson’s every hour – and the COVID-19 pandemic has increased complications with regards to delays and misdiagnoses.
However, he called the new results “significant” in the bid to revolutionise Parkinson’s treatment.
The Professor added: “With this innovative test, we could see people being diagnosed quickly and accurately enabling them to access vital treatment and support to manage their Parkinson’s symptoms sooner.”
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Police release footage of missing Manchester man Adeo Alston-Ekpei’s last-known movements
Emily Sergeant
Video footage showing the last-known movements of a Manchester man who’s been missing for three weeks now has been released.
Detectives at Greater Manchester Police (GMP) are continuing to search for Adeo Alston-Ekpei, who has not been seen since Friday 16 May.
The 25-year-old was seen in Fletcher Moss Park in Didsbury at around 3pm, before later being seen walking down Kingsway away from Manchester and close to the River Mersey, at around 5.20pm that same day.
Multiple lines of enquiry being explored by police at present, but anyone who believes they may have seen him from around this time, is asked to get in touch.
Adeo is described as being a mixed-race male, with long curly black hair and a long singular dreadlock, and bleached eyebrows. He has a cupid’s bow piercing and a right eyebrow piercing. He also has an ‘AKA’ tattoo on his right wrist, and a ‘24’ tattoo in the right side of his chest.
He was last seen wearing long blue denim shorts, an undone green short-sleeved button-up shirt, and white Adidas trainers.
Friends have also recently set up a public fundraiser to help with the search for Adeo.
Adeo Alston-Ekpei has been missing for almost three weeks / Credit: GMP
“We are dedicated to finding Adeo and getting much-needed answers for his family,” commented Detective Inspector Kelly, from GMP’s Manchester district, as the footage was released to the public this week.
“I would ask any residents around the Kingsway area, and surrounding housing estates off Kingsway into Gately, and who may have dashcam or CCTV footage from around this time, to please check and get in touch if you have any information.
“Likewise, if anyone believes they have seen Adeo, please get in touch with one of our officers. Any information is appreciated and investigated as we continue our work.”
#MISSING | We are continuing to ask for information relating to missing Adeo, who was last seen on May 16.
We have additionally released CCTV footage showing Adeo’s last known movements on Kingsway, Manchester.
— Greater Manchester Police (@gmpolice) June 5, 2025
A spokesperson for Adeo’s family described the missing man as ‘kind, funny, and intelligent’ with a ‘huge heart’, but they say he ‘wasn’t himself when he disappeared’.
“He may have come across as agitated, lost, or confused,” the spokesperson admitted. “In his last call to his mum, he was in a very vulnerable state.”
Anyone with any information regarding Adeo’s whereabouts is urged to contact South Manchester CID directly on 0161 856 6051 or 0161 856 6063, or you can use the LiveChat function on GMP’s website and quote log number 838 of 18/05/25.
Alternatively, you can report information to Crimestoppers anonymously on 0800 555 111.
Featured Image – GMP
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Tributes pour in after Heaton Park’s beloved resident donkey Ralph dies at age 40
Emily Sergeant
The time has come… one of Heaton Park’s beloved resident donkeys, Ralph, has sadly died at the impressive age of 40.
As regular visitors to Manchester‘s largest park may be aware, Ralph the donkey recently celebrated his 40th birthday – which, even more impressively, actually made him 120 in donkey years – and it was a truly incredible achievement for him to reach, especially as The Donkey Sanctuary says that the average life expectancy for a donkey is just over 30 years of age.
But earlier this week, things sadly took a turn for the worse.
Heaton Park‘s Estates Team made the decision to contact a vet for a site visit after identifying some changes with Ralph’s behaviour, and unfortunately, this was found to be caused by a ruptured intestine.
So it’s with ‘deep sadness’ that the park had to announce to the public that Ralph passed away later that afternoon.
“Ralph meant a lot to many, both staff and all our visitors, and he will be deeply missed within the park,” Heaton Park & Hall said in tribute to their beloved friend on social media this week.
They also shared an adorable image of him when he was just a young foal.
Those who had the pleasure of seeing Ralph roam the park over the past four decades soon began flooding the comments, sharing their own emotional tributes to the friendly face who’s sadly no longer with us.
Heaton Park’s beloved resident donkey Ralph celebrating his 40th birthday / Credit: Heaton Park & Hall (via Facebook)
“Sleep easy buddy, you had a wonderful charmed life and you deserved it,” one touching comment read on Facebook, while another added: “Aww Godspeed Ralph, you had a happy life, now its time to rest,” and a third commented: “So sorry to hear this sad news about Ralph, but glad to know he has enjoyed a long and happy life.”
Another tribute reads: “RIP Ralph, you brought a lot of joy to a lot of people,” as does this similar one: “Aww bless him. He’d had a long and happy life, and gave much happiness too.”