Parkinson’s Disease could be diagnosed with skin swab tests, Manchester scientists discover
Scientists at the University of Manchester have made a “game-changing” breakthrough by discovering that Parkinson’s Disease could be diagnosed using a simple skin swab test.
Scientists at the University of Manchester have made a “game-changing” breakthrough by discovering that Parkinson’s Disease could be diagnosed using a simple skin swab test.
Results published this week showed that Parkinson’s sufferers may produce higher amounts of a substance called sebum – which coats and protects the skin.
A swab test can detect these compounds; and may help researchers determine whether new treatments are able to slow, stop or reverse the progression of the disease.
The study was funded following the case of Joy Milne – a woman who stunned scientists by revealing she could detect Parkinson’s disease through smell.
Joy told researchers that she could smell a “musky” odour on her husband Les – who was diagnosed with Parkinson’s years later.
Professor Perdita Barran, Professor of Mass Spectrometry at UoM, said the results were “an extremely encouraging step” towards tests that could be used to help diagnose and monitor Parkinson’s.
“Not only is the test quick, simple and painless but it should also be extremely cost-effective because it uses existing technology that is already widely available,” said the professor.
“We are now looking to take our findings forwards to refine the test to improve accuracy even further and to take steps towards making this a test that can be used in the NHS and to develop more precise diagnostics and better treatment for this debilitating condition.”
Parkinson’s can be difficult to diagnose / Image: Pixabay
Parkinson’s UK analysis suggests that 1 in 37 people will be diagnosed with Parkinson’s in their lifetime.
The onset of the disease – which sees the sufferer develop a range of physical symptoms such as tremors and stiff, slow movements – is often gradual; worsening over a period of months and years.
The condition can be difficult to diagnose, too.
In a recent survey of more than 2,000 people with Parkinson’s, more than a quarter revealed they were initially misdiagnosed with a different condition.
It took four years for Daxa Kalayci, 56, to be given an accurate diagnosis of Parkinson’s.
“Despite my diagnosis eventually being confirmed by a DaTscan, a quick and simple diagnostic test for Parkinson’s would have given me the chance to start my treatment earlier and enjoy life a lot more,” said Daxa.
“But instead, I lost so many years not being able to pursue a career as a paramedic or go back to nursing.
“This test could be a game-changer for people living with Parkinson’s and searching for answers like I was.”
Professor David Dexter, Associate Director of Research at Parkinson’s UK said that two more people in the UK are diagnosed with Parkinson’s every hour – and the COVID-19 pandemic has increased complications with regards to delays and misdiagnoses.
However, he called the new results “significant” in the bid to revolutionise Parkinson’s treatment.
The Professor added: “With this innovative test, we could see people being diagnosed quickly and accurately enabling them to access vital treatment and support to manage their Parkinson’s symptoms sooner.”
News
Urgent appeal issued following serious road traffic collision involving motorcyclist on M60
Emily Sergeant
An urgent appeal has been issued following a serious road traffic collision on the M60.
Greater Manchester Police (GMP) are appealing for information and dash-cam footage, as well as urging witnesses to come forward, after a motorcyclist suffered life-threatening injuries during a collision on the M60 this past Saturday (12 July).
Shortly after 1:40pm, police were called a report of a collision involving a motorbike on the anti-clockwise side of the motorway, between junctions 25 and 24.
When patrols responded and arrived on the scene, they found a man in his 50s – believed to be the motorcyclist – with life-threatening injuries, and was subsequently taken to hospital for treatment in an air ambulance, with his family being informed in the process.
An urgent appeal has been issued following a serious road traffic collision involving motorcyclist on the M60 / Credit: Wikimedia Commons
The M60 was closed in one direction, between Bredbury and Denton, following the crash from around 2:30pm onwards, and all traffic was diverted while investigations were ongoing.
GMP’s Serious Collision Investigation Unit is in the process of conducting enquiries, and at this time, it isn’t believed that any other vehicle was involved in this incident.
This is why police are appealing for anyone who may have witnessed the collision, or who has dash-cam footage, to get in on contact.
Police have also thanked the members of the public who stopped by the roadside to give the man initial first aid before emergency services arrived.
Police issue update on Oasis arrests and fence-jumpers
Daisy Jackson
Greater Manchester Police have shared an update on the arrests made at the opening two nights of Oasis Live ’25.
More than 100,000 people have flocked up to Heaton Park on Friday and Saturday evening for the first two of five Oasis reunion shows.
And largely, things have gone without a hitch, with only 15 arrests made so far.
The majority of these are arrests on suspicion of fraud, with five men and a woman in three separate incidents attempting to access the Oasis gig with fake accreditation.
Another man was arrests on suspicion of assaulting a member of security staff.
Two more men were arrested on suspicion of assault – a section 18 inside the Oasis gig at Heaton Park, and another for a section 47 outside.
Police have also said that ‘a number of people’ have attempted to access the gigs without tickets, with a perimeter gate breached on Saturday night, but ‘failed to do so’.
Five drones which breached airspace restrictions were seized on Friday.
A Section 34 Dispersal Order, which gives officers the power to direct individuals to leave a specified area and not return for 48 hours, has been in place for each night of the Oasis concerts so far.
This will be re-assessed before each concert this week, with the Gallagher brothers back at Heaton Park on Wednesday, Saturday and Sunday.
GMP around Manchester ahead of the Oasis reunion shows. Credit: GMP
Assistant Chief Constable Matt Boyle said: “We have been planning for these events for several months, working with partners and the organisers to make sure everyone can enjoy the concerts safely. To that end, I’m pleased to say that the first two Oasis homecoming events have been a success.
“What has been especially pleasing is how more than 100,000 people have enjoyed these iconic events safely and without trouble.
“We will have a highly visible presence in and around Heaton Park, and across the city, to ensure the next three events continue to pass safely.
“A number of people without tickets attempted to gain entry through a perimeter gate on Saturday night but failed to do so.
Credit: The Manc GroupCredit: Tiktok benwalkerofficialPolice say ‘just 15’ arrests made at Oasis so far
“We continue to support the event organisers and the local authority with their plans preventing any unauthorised access to the arena site.
“While arrests have thankfully been minimal, we have had to take some suspects to custody, including one after an alleged assault on a steward on Saturday night. We will not tolerate any abuse of anyone doing their job.
“On Friday night we also dealt with a number of breaches of airspace restrictions involving drones where our officers seized five drones and spoke to two other pilots.
“We continue to have airspace restrictions in place on the nights of the concerts and anyone found breaching the one-and-a-half-mile restriction zone could face prosecution.”