Parkinson’s Disease could be diagnosed with skin swab tests, Manchester scientists discover
Scientists at the University of Manchester have made a “game-changing” breakthrough by discovering that Parkinson’s Disease could be diagnosed using a simple skin swab test.
Scientists at the University of Manchester have made a “game-changing” breakthrough by discovering that Parkinson’s Disease could be diagnosed using a simple skin swab test.
Results published this week showed that Parkinson’s sufferers may produce higher amounts of a substance called sebum – which coats and protects the skin.
A swab test can detect these compounds; and may help researchers determine whether new treatments are able to slow, stop or reverse the progression of the disease.
The study was funded following the case of Joy Milne – a woman who stunned scientists by revealing she could detect Parkinson’s disease through smell.
Joy told researchers that she could smell a “musky” odour on her husband Les – who was diagnosed with Parkinson’s years later.
Professor Perdita Barran, Professor of Mass Spectrometry at UoM, said the results were “an extremely encouraging step” towards tests that could be used to help diagnose and monitor Parkinson’s.
“Not only is the test quick, simple and painless but it should also be extremely cost-effective because it uses existing technology that is already widely available,” said the professor.
“We are now looking to take our findings forwards to refine the test to improve accuracy even further and to take steps towards making this a test that can be used in the NHS and to develop more precise diagnostics and better treatment for this debilitating condition.”
Parkinson’s can be difficult to diagnose / Image: Pixabay
Parkinson’s UK analysis suggests that 1 in 37 people will be diagnosed with Parkinson’s in their lifetime.
The onset of the disease – which sees the sufferer develop a range of physical symptoms such as tremors and stiff, slow movements – is often gradual; worsening over a period of months and years.
The condition can be difficult to diagnose, too.
In a recent survey of more than 2,000 people with Parkinson’s, more than a quarter revealed they were initially misdiagnosed with a different condition.
It took four years for Daxa Kalayci, 56, to be given an accurate diagnosis of Parkinson’s.
“Despite my diagnosis eventually being confirmed by a DaTscan, a quick and simple diagnostic test for Parkinson’s would have given me the chance to start my treatment earlier and enjoy life a lot more,” said Daxa.
“But instead, I lost so many years not being able to pursue a career as a paramedic or go back to nursing.
“This test could be a game-changer for people living with Parkinson’s and searching for answers like I was.”
Professor David Dexter, Associate Director of Research at Parkinson’s UK said that two more people in the UK are diagnosed with Parkinson’s every hour – and the COVID-19 pandemic has increased complications with regards to delays and misdiagnoses.
However, he called the new results “significant” in the bid to revolutionise Parkinson’s treatment.
The Professor added: “With this innovative test, we could see people being diagnosed quickly and accurately enabling them to access vital treatment and support to manage their Parkinson’s symptoms sooner.”
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Kalvin Phillips is reportedly set to be reintegrated into the Manchester City squad
Danny Jones
Long-exiled Manchester City player Kalvin Phillips is reportedly on the verge of being reintegrated into Pep Guardiola’s squad this season.
The ex-Leeds United star, who signed for the Blues back in 2022, has still only made just 16 appearances for the club, but could now be eyeing up a potential renaissance.
Man City have made plenty of signings this year, but with a number of outgoings and several injuries in key positions, it looks like there could be an avenue for the one-time England international to fight his way back into the team.
As per Telegraph Sport‘s Mike McGrath, Kalvin Phillips is set to be reintroduced to City’s 25-man Premier League selection; the question is, can he make it into a first-team XI?
🚨 EXCLUSIVE: Kalvin Phillips has chance to resurrect career at the Etihad Stadium after failed loan spells with Ipswich and West Ham
According to McGrath, Phillips will be “given a chance to resurrect his career at the Etihad Stadium” with the meat and potatoes of the 2025/26 campaign still yet to get properly underway.
Now 29, the Yorkshireman is well and truly within the crucial ‘prime’ years as an athlete, and after such an extended period on the sidelines, he’ll be more motivated than anyone to get his career back on track.
The central defensive midfielder – who was formerly considered a key cog in the middle of the park for Leeds – has spent two loan spells away from the Etihad, but neither really worked out for the undeniably talented footballer.
Having joined West Ham for the latter portion of the 23/24 term and spending the last 12 months on loan at struggling Ipswich Town, his time at both clubs was pretty forgettable, punctuated by little more than a couple of unfortunate red cards and more time on the bench.
Speaking to Sky Sports fairly recently, he confessed that the last couple of years have been very difficult and was visibly emotional discussing his struggles since moving to Man City.
It’s also worth noting that Guardiola himself has admitted to feeling “so bad” for Kalvin Phillips’ situation – perhaps why he now looks like he could be given a second chance.
CDM-wise, Rodri and Nico González are considered the go-to options, but Stockport-born Rico Lewis and Mateo Kovačić have also been used in the role.
Once again, although Man City face somewhat of an injury crisis ahead of the Manchester derby this weekend, any prolonged absences could at least see an opportunity arise for the forgotten man.
What do you make of Kalvin Phillips’ chances of being restored to the Manchester City squad and maybe even putting himself back into national team contention ahead of the World Cup?
Featured Images — Sky Sports (screenshot via YouTube)/pantkiewicz (via Flickr)
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Brand new venue confirmed as the host of The Manchester 24 Hour Run Against Homelessness
Danny Jones
The magnificent Manchester 24 Hour Run Against Homelessness is back this year, and with the 2025 event fast approaching, they have announced arguably their biggest host venue yet, setting up in camp in a brand new food and drink hall.
Having housed the incredible charity gathering from Freight Island last year, it was always going to take some beating this time around, but somehow they’ve managed to.
The annual relay run in aid of Greater Manchester’s homeless community will be taking place at none other than the city centre’s recently unveiled House of Social, with the building’s wider student living quarters serving as the perfect fit for the initiative first thought up by university friends back in 2018.
Announced this week, House of Social will be teaming up with the wider First Street neighbourhood to look after the hordes of incredible runners this year.
Jamie Hills, Development Director at Ask Real Estate – who operate the ever-growing First St complex – said of volunteering as this year’s hosts: “First Street is thrilled to welcome and fuel the incredible runners of The Manchester 24 Hour Run Against Homelessness.
“As the city’s hotspot for community events and culture, we’re proud to be a place where community thrives, so we’re incredibly excited to support this important initiative. With our fantastic on-site amenities like House of Social, we’re ready to keep those participating powered up and going strong!”
As for co-founder Tom Lewis, speaking to The Manc, he said: “We’re excited to return for our 7th edition, with Manchester being our flagship event.
“Through being hosted at House of Social in First Street, we’re hoping to make this year’s edition the best and biggest yet, aiming to raise £50,000 for the Greater Manchester Mayor’s Charity Scheme, ‘A Bed Every Night’.
“We’d love to see you all at the event, plus bring your friends and workplace to. There are paces for everyone, including walking laps.”
In November 2024, not only did the fundraising phenomenon mark its first-ever expansion with an inaugural event in Birmingham, but it also surpassed £50,000 here in Manchester alone, and is now set to make debuts in a trio of new cities.
Tom went on to add: “I couldn’t be more proud of what we’ve managed to accomplish as a team with starting up three more events across the country this year and expanding Manchester to a scale we couldn’t have dreamed of when we started out seven years ago.”
We here at The Manc Group have been helping The MCR 24 Run Against Homelessness for several years now, and have put in plenty of those 5k laps between ourselves, so you can bank on us being there to put in some more hard yards this November.
Even better still, we’ve already roped in our friends over at The Hoot to help out with the maiden 24 Hour Run Against Homelessness in Leeds, and we hope to see lots more of you chipping in across the North and beyond.
Here’s to helping rough sleepers find beds and get back on their feet all over the country.
The @mcr24hourrun is expanding in 2025 and is heading to Leeds for the first time. 🏃♂️
And they're not the only city making their debut this year either… 👊