A Manchester man who was told he had just a year left to live has now been given the all-clear from cancer after a groundbreaking drug trial.
51-year-old Robert Glynn from Worsley in Salford is a massive Manchester United fan, enjoys playing snooker, golf, and fishing, and previously worked as a welder before his health turn a took and he went to his doctor with a severe pain in his shoulder that was preventing him from sleeping properly, and eventually developing an infection in his gall bladder.
After several scans and blood tests, Robert got the got the devastating news that he had intrahepatic bile duct cancer back in August 2020 – in the middle of the COVID-19 pandemic and the day before his 49th birthday.
Intrahepatic bile duct cancer – which is also known as biliary tract cancer – is a rare cancer that forms in the bile ducts inside the liver, with only around 1,000 people in the UK diagnosed with this type of disease each year, and only around 5% of people living for five years or more after diagnosis.
Sadly, not only is there a poor prognosis and few treatment options for this type of cancer, Robert’s cancer was at such an advanced stage that it was now in his liver and had spread to his adrenal gland too.
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So, he was referred to The Christie and offered the opportunity to participate in a clinical trial.
Robert Glynn from Manchester was given a year to live after being diagnosed with an aggressive form of cancer, but he is now disease-free thanks to a clinical trial at The Christie.
After showing an interest in taking part in the trial, Robert’s tumour sample was sent off for molecular analysis to check for any alterations, and it was found that his tumour had a high mutation burden – which means there was large numbers of genetic mutations in the cells – and this indicated that he may potentially have a good response to immunotherapy, which is a type of cancer treatment that helps the body’s immune system fight cancer.
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Based on these results, Robert was recommended to start a clinical trial with an immunotherapy drug already-approved for use in the UK, combined with the standard chemotherapy.
The treatment was administered intravenously.
The immunotherapy treatment together with chemotherapy proved so successful that it helped shrink the tumour in Robert’s liver and adrenal gland, and meant he was able to have surgery in April this year, which miraculously found only ‘dead tissue’ and showed that treatment combination killed-off all the cancer cells.
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Since the operation, Robert hasn’t needed any more treatment and his three-monthly scans show that he’s now clear of cancer.
Manchester man given a year to live now cancer-free after groundbreaking drug trial / Credit: The Christie NHS Foundation Trust
“I wouldn’t be here today without the trial,” Robert reflects.
“When I was given the option to take part in research, I jumped at the chance. You do anything you can to extend your life… and it’s important to remain positive and not give up. It’s never over until it’s over.”
Robert said getting the all-clear was “overwhelming”.
He continued: “In an odd kind of way having the diagnosis has turned my life around.
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“With my partner, Simone, we get out in nature and walk loads. When something like this happens you realise life is for living.”
Oncologists worldwide are now eagerly awaiting the results of the research into Robert’s case, as this, along with a further study with more patients, could lead to a change in the treatment of biliary tract cancer.
Featured Image – The Christie NHS Foundation Trust
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New £60m fund launched to fill potholes across Greater Manchester
Emily Sergeant
A new £60 million Pothole Fund has been created to repair more of the city region’s roads and pavements.
The fund – which has been set up by new Mayor Bev Craig, and is to be spent across every borough in Greater Manchester – is set to be a ‘major boost’ to efforts to tackle the pothole problem, as it will be enough to repair and maintain over a million square metres, or around 125 kilometres, of road across the wider region.
Around 2.5 billion trips are made on Greater Manchester‘s roads every year – not only by motorists, but also by buses, trams, cyclists, and pedestrians. So the fund will be used to help keep the highways network ‘safe and reliable’.
The fund will enable transport teams to repair hotspots where surfaces are in poor condition, as well as resurface roads and pavements to prevent them from deteriorating in the first place.
A new £60m fund has been launched to fill potholes across Greater Manchester / Credit: TfGM
Cold and wet winters, more traffic, and heavier vehicles using the roads are just some of the contributing factors to the pothole problem, which is why the fund is being introduced before autumn and winter properly arrives.
The amount each of the 10 boroughs will receive is based on an agreed funding formula, with the allocations being:
Bolton: £6,552,000
Bury: £4,374,000
Manchester: £8,155,000
Oldham: £5,258,000
Rochdale: £5,243,000
Salford: £5,388,000
Stockport: £6,820,000
Tameside: £4,980,000
Trafford: £4,992,000
Wigan: £8,241,000
The extra cash comes from the region’s transport budget, with leaders agreeing to reallocate funding towards highways maintenance, and it fulfils a commitment Bev made in her Mayoral Manifesto to repair more roads and make sure pavements are safe.
“Keeping our roads and pavements safe and well maintained is essential for a growing city region like Greater Manchester,” explained Mayor Bev Craig.
“That’s why I promised to create this new Pothole Fund that will benefit drivers and everyone who uses our roads to get around. Properly maintaining our roads will save motorists money on costly repairs, and by preventing potholes forming in the first place, councils won’t have to spend as much money on emergency road repairs.
“This issue came up repeatedly on the doorstep during my election campaign so I’m pleased that I can do something about it so quickly, building on the significant work already planned by councils across Greater Manchester.”
Featured Image – TfGM
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Six GMP officers dismissed following racial discrimination allegations
Emily Sergeant
A number of police officers have been dismissed following an internal investigation, Greater Manchester Police (GMP) has confirmed.
Following the internal investigation into alleged racial discrimination against an officer on the Bury district – which was launched by GMP‘s Professional Standards Directorate in July 2024 – six officers and two former officers were found to have committed gross misconduct, and a ninth officer was found to have committed misconduct.
The investigation came after a report was made that an officer had been subjected to ‘racist behaviour’ by colleagues in December 2023.
The panel heard how PC Y – who has African heritage and has been granted anonymity – made a complaint after her accent was mimicked by a group of officers. She was also compared to a suspect with similar skin colour, and one of the dismissed PCs made a derogatory comment about her hair.
PC Y was supported and kept updated throughout the investigation, GMP assured, as well as providing evidence at the hearing.
The misconduct hearing lasted just over two weeks, with the panel concluding that the officers breached the Standards of Professional Behaviour relating to Equality and Diversity, Authority, Respect, and Courtesy.
The six officers who have been dismissed are PC Demi Green, PC Heena Rani, PC Lucy Granby, PC Matthew Barlow, PC Matthew Hill, and PC Mohammed Abid, while the former officers who were found to have committed gross misconduct are PC Jake Holt, and former Officer A – who has been granted anonymity.
The panel also found that Sergeant Adrian Bick’s actions amounted to misconduct, as there was no breach of the standard of equality and diversity.
As a result, the six serving officers have been sacked without notice, while the two former officers would have been dismissed had they not already left the force, and Sergeant Bick was issued a written warning.
“No officer or member of staff should have to come to work and experience discriminatory behaviour from the people they serve alongside,” declared Deputy Chief Constable, Terry Woods.
“Everyone has the right to feel respected, valued and part of the same team with a shared commitment to serving our communities and keeping people safe.”
Emily Sergeant -
30th December 2022 
