A new study has found that a “game-changing” antibiotic could save millions of lives worldwide from drug-resistant superbugs.
After a team of dedicated UK scientists and researchers were able to use the drug to successfully eradicate methicillin-resistant staphylococcus aureus – a so-called superbug known as MRSA, which is resistant to several widely used antibiotics – in a study on mice, it’s now been hailed as a medical breakthrough.
The breakthrough involved the development of new versions of the molecule teixobactin.
Teixobactin is said to be capable of killing bacteria without damaging the tissue of the mammals it was tested on.
It was first hailed as a “game-changing” antibiotic in 2015, but according to scientists, this new project developed “synthetic” classes of the drug, and because the synthetic versions can be kept at room temperature, global distribution is now much easier.
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A new study has found that a “game-changing” antibiotic could save millions of lives worldwide from drug-resistant superbugs / Credit: Mark Fletcher-Brown (via Unsplash)
Although global health officials have repeatedly warned about the rise of drug-resistant bacteria and other microbes due to the misuse and overuse of antibiotics – which encourages microorganisms to evolve into “superbugs” – however, future patients could soon be treated with just a single daily dose of teixobactin for systemic life-threatening resistant bacterial infections.
This antibiotic breakthrough comes after the latest figures, according to a January 2021 study in The Lancet, found that in 2019, more than 1.2 million people died from antibiotic-resistant bacterial infections.
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Additionally, an AMR review commissioned by the UK government has predicted that by 2050, an extra 10 million people will die as a result of drug-resistant infections each year.
Dr Phil Packer, from Innovate UK – the agency which delivered the latest project – said the results had been “excellent”, adding that new classes of antibiotics were especially needed to tackle AMR because existing molecules were already familiar to bacteria, which makes resistance development more likely.
The breakthrough involved the development of new versions of the molecule teixobactin / Credit: Global Panorama (via Flickr)
“We are delighted with results, which have validated synthetic teixobactin’s promise to tackle resistant bacterial infections when currently used antibiotics fail,” he added.
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“We look forward to following this journey closely in future.”
Speaking on the breakthrough, Health Secretary Sajid Javid added: “It is fantastic to see such innovative work like this happening in the UK – another clear example of this country being at the forefront of scientific advancements which can benefit people across the world.”
No trams to run on three major Greater Manchester lines this Easter bank holiday weekend
Emily Sergeant
People are being urged to ‘plan ahead’ as no trams are set to run on three major Greater Manchester Metrolink lines this weekend.
As part of a continuing £150 million investment in the Metrolink network across the region, Transport for Greater Manchester (TfGM) has announced that more than 1km of track will be replaced on the Altrincham line, and work will also take place between Trafford Bar and Deansgate-Castlefield to prepare for full track replacement later in the year.
As a result, there will be no trams on the Altrincham, Eccles, and Trafford Park lines this Easter bank holiday weekend all day from Friday 3 to Monday 6 April.
On top of these line closures, there is also set to be disruption across other parts of the network too, as on the East Didsbury and Manchester Airport lines, trams will run to Firswood only, and services on the Rochdale line will terminate at Exchange Square.
To keep people moving over the four-day weekend, replacement buses will run between all the affected stops, TfGM has confirmed.
Anyone using a replacement bus, however, will still need a valid Metrolink ticket or a one-day Bee bus ticket to travel, and customers will be able to use all existing options to buy these, as they will not be able to buy a ticket or pay for the fare on the replacement buses themselves.
No trams will be running on three major Greater Manchester lines this Easter bank holiday weekend / Credit: TfGM
Replacement buses are said to be calling at ‘all affected stops’ along the lines, so customers are being told not to worry about that.
Speaking ahead of the improvement works being carried out this weekend, Ian Davies, who is the Network Director for Metrolink at TfGM, said: “The first main upgrades of the year get under way over the Easter weekend, as our £150m programme to improve our network continues.
“We’ll be doing everything we can to minimise disruption to passengers while we carry out this essential work to ensure our tram network remains reliable, resilient and safe for years to come.”
TfGM has assured that staff will be out and on-hand across the network this weekend, but is urging anyone travelling to plan for their journeys ahead of time to make sure they go as smoothly as possible.
Looking ahead to the rest of the month, no trams will run between Piccadilly Gardens and Ashton-under-Lyne on Saturday 11 and Sunday 12 April while the track is repaired, and a further weekend closure for track repairs on the Ashton line will take place on Saturday 25 April and Sunday 26 April.
Find out more and plan ahead on the Bee Network’s dedicated webpage here.
Featured Image – Janus Boye
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Three men arrested after ‘shocking’ Salford pub fight leaves victim in life-threatening condition
Emily Sergeant
Three men have been arrested as police continue to appeal following a ‘shocking’ incident in Salford over the weekend.
Greater Manchester Police (GMP) explained that, at around 2:51am yesterday (Sunday 29 March), officers were called to reports of an assault at a pub on Liverpool Road in Irlam, where it’s understood that an incident involving several males took place.
Police quickly attended the scene, and one male was rushed to hospital.
The man sustained serious injuries and was taken to hospital for treatment, where he’s said to remain in a life-threatening condition.
While officers are working ‘at speed’ on their investigation to establish the full circumstances of this incident, a scene is currently in place, and road closures are affecting the immediate area.
At this time, it has been confirmed that three men – all in their 20s – have been arrested on suspicion of Section 18 assault, and they remain in custody for further questioning while GMP renews its public appeal for information.
“This is a shocking incident and our thoughts are firmly with the victim and his family during this extremely difficult time,” commented Detective Chief Inspector Helen Bagnall, from GMP’s Salford district. “We are working at pace and remain absolutely committed to identifying everyone involved and bringing those responsible to justice.
“Three arrests have been made in connection with this incident, and we are continuing to appeal for further information.
“Officers remain committed to understand the full circumstances and are urging anyone with information to come forward to support our investigation.”
Can you help? A dedicated online Major Incident Public Portal has been set up, and information, CCTV, dashcam, doorbell, and phone images and footage can be submitted here, or you can also contact police on 101, quoting log 256 of 29/03/26.
Alternatively, you can contact Crimestoppers, anonymously, on 0800 555 111.
Emily Sergeant -
29th March 2022 
