Alzheimer’s Research UK has hailed the drug lecanemab as a ‘truly historic moment’ for dementia research after trials found it can slow the rate of decline in people’s memory.
Results from a three-phase clinical trial have been published today by pharmaceutical company Eisai.
The data has shown that the drug can help Alzheimer’s patients over 18 months and help them with day-to-day activities.
The trial included 1,795 people in the early stages of the disease, who received bi-weekly infusions of either lecanemab or a placebo.
Alzheimer’s Research UK has said that the findings represent a ‘major step forward’ for dementia research.
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They noted, however, that lecanemab did come with significant side effects.
Credit: Unsplash
Dr Susan Kohlhaas, Director of Research at Alzheimer’s Research UK, said: “These exciting findings represent a major step forward for dementia research and could herald a new era for people with Alzheimer’s disease. This is the first time a drug has been shown to both reduce the disease in the brain and slow memory decline in clinical trials.
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“Lecanemab works by clearing the amyloid protein that builds up in the brain in people with Alzheimer’s disease. In this trial, the drug slowed down participants’ decline in memory and thinking, and their ability to carry out day-to-day activities. Although the benefits were small and came with significant side effects, it marks the arrival of a treatment that can slow the course of Alzheimer’s disease.
“With all this excitement, there are still many questions and challenges we need to address.
“The treatment window in the trial was for 18 months, so we don’t yet know whether there will be impacts to people that last beyond this. Longer-term studies that are ongoing will tell us whether the modest improvements seen in the trial change the trajectory of the disease longer-term.
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“Lecanemab was associated with severe side effects, and it will be important for regulators to understand the safety profile of the drug before it is given a full license for use.
“The benefits of taking lecanemab in the trial were modest but the challenge and opportunity remains within dementia research to build on these findings into an era where we’re developing multiple treatments against different aspects of Alzheimer’s disease to slow and stop the disease.
“It’s safe to say that the NHS is not ready for a new era of dementia treatment.
“We estimate that unless there are drastic changes in how people access specialist diagnostic tests for Alzheimer’s disease, only 2% of people eligible for drugs like lecanemab will be able to access them. We recommend, through the new Dementia Mission, the government take urgent steps to bring together regulators, industry, clinicians and decision-makers in our health system to put a clear plan in place to ensure people in the UK are among the first in the world to access new treatments once they are licensed.
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“This is truly a historic moment for dementia research. This year is the 30th anniversary of the seminal work that revealed the central role of amyloid protein in Alzheimer’s. The road to an anti-amyloid treatment has been a long one and people with Alzheimer’s have seen many disappointing setbacks.
“We hope that this drug will make it to patients, but it won’t be suitable for everyone with Alzheimer’s, and it’s only a first step on the journey towards a cure.”
Featured image: Unsplash
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Teen sentenced after deliberately driving into a female police officer in Stockport
A teen who deliberately drove into a female police officer at a retail park Stockport earlier this year has been sentenced.
Harvey Bell was at a retail park on Wilmslow Road in Cheadle back on 25 January 2025 when he seriously injured a Greater Manchester Police (GMP) officer during a shocking incident – which left the officer requiring hospital treatment.
At the time, the 19-year-old from Knutsford was present while police were investigating reports of class C drug use in a car park.
Police parked in front of an Audi and the officer signalled for Bell to remain stationary and turn the engine off, but instead he reversed, and as the officer approached the front windscreen, Bell drove at the officer, knocking her to the ground.
He then proceeded to drive over her legs with both sets of wheels, before heading out of the car park at speed.
#JAILED | A man who deliberately drove into a police officer in Stockport has been jailed.
Harvey Bell (12/08/2005) has been sentenced to 31 months in a Young Offenders Institute and was disqualified from driving for two years.
— Stockport Police (GMP) (@GMPStockport) June 4, 2025
Bell was subsequently arrested the following day and made no comment in his police interview, but then went on to plead guilty to causing serious injury by dangerous driving, as well as possession of cannabis on 27 March 2025.
The teen appeared at Manchester Crown Court this week where he was sentenced to 31 months in a Young Offenders Institute, and was also disqualified from driving for two years – which will take effect when he is released.
“What [Bell] did to me is permanently in the back of my mind, every call I go to, I feel the apprehension, the fear that any incident, no matter how innocuous it appears, can end with being assaulted or hurt,” the officer explained in a powerful victim impact statement read in court.
“This is an unseen result of Bell’s assault on me.”
She continued: “I know that Bell’s abhorrent behaviour is an exception, and the majority of the public we serve do not wish us harm, but assaults on police need to stop. An attack on a police officer is an attack on us all.
“Bell is a danger to society and had total disregard for my life.”
Featured Image – GMP
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IKEA announces decision to close popular Greater Manchester site
It’s the end of the road for one of IKEA’s popular Greater Manchester sites.
The Swedish furniture giant has announced its decision to close its ‘Plan and Order Point’ over in Stockport in a couple of weeks time.
The store – which is located in Stockport town centre’s Merseyway Shopping Centre – launched to huge success back in March 2023, and at the time, was the second of this ‘test and trial’ format to open in the UK, becoming a smaller space dedicated to kitchen and home planning, as well as ordering items.
IKEA says the closure comes as a result of ‘valuable learnings’ which plan to take this conceptual format in a direction to ‘better suit the needs of UK customers’.
IKEA is closing its close popular Stockport site this month / Credit: Jon Super (via IKEA)
Since the opening of the Stockport Plan and Order Point, IKEA claims it has seen an increased demand for Click and Collect services, a desire by customers to shop a smaller selection of home furnishing accessories, as well as the ability to return goods to physical IKEA units, and this is all something which the current location is unable to offer.
Learning from this change in consumer habits, the company says its future Plan and Order Point openings – including in those in other northern cities like Hull and York – will offer these services.
IKEA says it also remains ‘committed’ to trialling new formats, such as its upcoming small stores, one of which will open in nearby Chester later this year.
Luckily for IKEA fans, the retailer has confirmed that its major Greater Manchester store in Ashton-under-Lyne, as well as the neighbouring store in Warrington, will remain open as normal, offering all the services available at Stockport and more.
The Swedish furniture says the closure comes as a result of ‘valuable learnings’ about customer needs / Credit: Jon Super (via IKEA)
In addition to the upcoming opening of a smaller store in Chester, IKEA has revealed that the North West continues to be an area of interest for future expansion.
“After careful evaluation, we’ve made the difficult decision to close the IKEA Plan and Order Point at Merseyway Shopping Centre,” explained Salma Azad, who is one of IKEA’s Area Managers.
“In the two years since opening, we’ve taken valuable learnings, including how our customers prefer to meet IKEA, and we’ll take these insights into future openings, to serve shoppers in a more impactful way.”
Thanks to last year’s Click and Collect expansion, Stockport residents can now pick up purchases from Tesco Extra Stockport and Tesco Extra Stretford, as well as the Manchester store and the upcoming small store in Chester.
Stockport Plan and Order Point’s final day of trading will be on 16 June.
Daisy Jackson -
30th November 2022 
