A clinical trials patient in Manchester is celebrating a new lease of life after having had “a remarkable response” to a new specific gene-targeting treatment that controls how cancer grows.
49-year-old Terri Hurdman, from Bromsgrove in Worcestershire, found out she had advanced bowel cancer on Valentine’s Day two years ago, and didn’t even think she’d make it past Christmas 2021 after finding herself left completely exhausted and out of breath from simple tasks such as climbing the stairs, walking a short distance, or even talking on the phone due to her cancer.
But within hours of trialling a new drug at The Christie NHS Foundation Trust, she was climbing stairs with no effort.
After three months, scans showed her tumours had halved in size.
Terri – who has three children and six grandchildren – was a previously fit and healthy factory worker used to doing manual work for a firm producing medical supplies, and had no symptoms until she got stomach ache and thought it might be IBS – but after having been referred by her GP to Kidderminster hospital, she was diagnosed with stage 4 colorectal cancer, which had spread to her lungs, and started chemotherapy a month later.
After three types of chemotherapy didn’t work, she was told she had no other options and was taken off the drugs.
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By August 2021, Terri had become very ill, had lost a stone and a half in weight, and was becoming weaker, so she was forced to use a wheelchair to get out and about, but luckily, her consultant at Kidderminster hospital knew The Christie in Manchester was running early phase clinical trials which used targeted therapies – a type of cancer treatment that targets the genes and proteins that control how cancer cells grow and spread – and referred her to see if the trial would be suitable.
Terri’s DNA had already been analysed as part of standard NHS testing, and it was found she had a mutation in the KRAS gene of her cancer.
Fortunately, the new international clinical trial was designed specifically for people with the gene mutation that Terri has, so she passed the screening and was recruited onto the trial, and immediately after taking the first dose of the tablets last October, her condition “improved significantly”, specialists at The Christie said.
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So much so, Terri was able to walk up some stairs without getting out of breath for the first time in months.
“It’s like a miracle. It really is a wonder drug as within days, I didn’t need to use the wheelchair at all, and I didn’t get out of breath climbing stairs, which would have previously led to a coughing fit,” Terri explained.
“That day, I spoke to my sister on the phone for an hour, something that would have wiped me out before, and my appetite came back, which made me look so much healthier, and the colour returned to my cheeks.
“I didn’t think I’d make it to Christmas, but now I’m looking forward to celebrating my 50th birthday in July.
Manchester firefighter surprises partner with proposal during new recruits parade
Danny Jones
We’re a sucker for a wholesome little video as we know you are, which is exactly why we thought of you lot when we came across this video of a newly graduated Manchester firefighter surprising his partner with a heartwarming proposal.
Just the kind of heartwarming that usually sets us off after a long week at work.
The clip shared by Greater Manchester Fire and Rescue Service (GMFRS) on Thursday, 25 April, shows Manc fireman James popping the question to his girlfriend sat unassumingly in the audience at a recent passing out ceremony.
Pass out ceremonies are when trainees go from recruits to fully qualified firefighters after completing their intensive operational training. It’s a long-standing tradition in the emergency services where friends and family gather to celebrate their achievements – it’s almost like it’s the perfect opportunity…
As you can see, since the graduates are usually the centre of attention, James couldn’t help but size his moment and instead of walking and lining up normally like everyone else, he decided to head straight over to his wife-to-be and get down on one knee.
You already know the rest.
Welling up immediately and barely able to remove her hands from her face, Melissa nods and says yes as the crowd cheers and the pair share a smooch.
Writing on social media, the GMFRS said: “We managed to capture a VERY special moment at our new recruits pass out parade today… Congratulations to James and Melissa!”, adding, “Certainly one way to start your new career”.
If we don’t see all the groomsmen dressed as firefighters on a random viral video sometime soon we’re going to be gutted.
All the best to the happy couple and if you’ve got any more lovely clips like this to send in so we can make ourselves cry (in a good way), you know what to do.
Featured Images — Greater Manchester Fire and Rescue Service
News
Peter Kay’s statement in full as his Co-op Live gigs are postponed for SECOND time
Daisy Jackson
Peter Kay has issued a statement after his two gigs at Co-op Live were rescheduled – again.
The Bolton-born comedian was supposed to officially open the huge new Manchester venue last week, but ‘power supply issues’ forced it to be rescheduled.
He was then supposed to perform on Monday and Tuesday of next week instead, but these two shows have been pushed back even further.
Peter Kay has now issued a statement addressing the postponement, saying it’s ‘very disappointing’.
He also said: “I know, I can’t believe it either.”
He’s even amended his own tour poster to add the disclaimer: “(If they actually open the place).”
The star joked that he was now the ‘ninth artist in the world’ to play there.
The legendary comic wrote: “To everybody with tickets, my apologies once again but unfortunately the Co-op Live still isn’t ready and so, as yet, remains untested for a large-scale audience.
“Consequently, they are having to reschedule my two shows yet again (I know I can’t believe it either).
“The first available dates the shows can reschedule to are as follows: Mon 29th April to Thurs 23rd May, Tues 30th April to Frid 24th May.
“Tickets will be transferred, or refunds given if the new dates aren’t suitable.
“It’s very disappointing but your safety is important, and I won’t compromise that.”
Co-op Live said in a statement: “Since making the difficult decision to postpone the live shows at Co-op Live due to take place this week, we have been undertaking an extensive protocol of testing critical procedures to ensure all areas are ready for fans.”
They’ve also made the rather bold decision to once again assure fans that the next raft of shows now set to be their opening gigs – big dates from Boogie Wit Da Hoodie and Olivia Rodrigo – are still set to go ahead as scheduled.
Touch wood.
“To ensure that we can run all shows safely, regretfully we have now had to take the decision to reschedule the planned The Black Keys and Peter Kay shows.
“Both The Black Keys and Peter Kay have graciously agreed to reschedule their shows. The Black Keys will now perform on 15 May 2024, and Peter Kay will now perform on 23 and 24 May 2024.
“All tickets remain valid and ticket holders will be contacted by their point of purchase. Refunds will be available for those who can no longer attend.
“We deeply appreciate the impact this will have on excited fans, and sincerely apologise for the inconvenience that this change will undoubtedly cause. Rescheduling Peter Kay and The Black Keys will give us the extra time we need to continue testing enhanced emergency communications thoroughly.
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“This is vital to satisfy the rigorous set of guidelines and protocols that are necessary for a venue of this size to ensure that our fans, artists and staff have the safest experience possible.”