A clinical trials patient in Manchester is celebrating a new lease of life after having had “a remarkable response” to a new specific gene-targeting treatment that controls how cancer grows.
49-year-old Terri Hurdman, from Bromsgrove in Worcestershire, found out she had advanced bowel cancer on Valentine’s Day two years ago, and didn’t even think she’d make it past Christmas 2021 after finding herself left completely exhausted and out of breath from simple tasks such as climbing the stairs, walking a short distance, or even talking on the phone due to her cancer.
But within hours of trialling a new drug at The Christie NHS Foundation Trust, she was climbing stairs with no effort.
After three months, scans showed her tumours had halved in size.
Terri – who has three children and six grandchildren – was a previously fit and healthy factory worker used to doing manual work for a firm producing medical supplies, and had no symptoms until she got stomach ache and thought it might be IBS – but after having been referred by her GP to Kidderminster hospital, she was diagnosed with stage 4 colorectal cancer, which had spread to her lungs, and started chemotherapy a month later.
After three types of chemotherapy didn’t work, she was told she had no other options and was taken off the drugs.
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By August 2021, Terri had become very ill, had lost a stone and a half in weight, and was becoming weaker, so she was forced to use a wheelchair to get out and about, but luckily, her consultant at Kidderminster hospital knew The Christie in Manchester was running early phase clinical trials which used targeted therapies – a type of cancer treatment that targets the genes and proteins that control how cancer cells grow and spread – and referred her to see if the trial would be suitable.
Terri is taking part in a new experimental drug trial at The Christie in Manchester / Credit: The Christie NHS Foundation Trust
Terri’s DNA had already been analysed as part of standard NHS testing, and it was found she had a mutation in the KRAS gene of her cancer.
Fortunately, the new international clinical trial was designed specifically for people with the gene mutation that Terri has, so she passed the screening and was recruited onto the trial, and immediately after taking the first dose of the tablets last October, her condition “improved significantly”, specialists at The Christie said.
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So much so, Terri was able to walk up some stairs without getting out of breath for the first time in months.
“It’s like a miracle. It really is a wonder drug as within days, I didn’t need to use the wheelchair at all, and I didn’t get out of breath climbing stairs, which would have previously led to a coughing fit,” Terri explained.
“That day, I spoke to my sister on the phone for an hour, something that would have wiped me out before, and my appetite came back, which made me look so much healthier, and the colour returned to my cheeks.
“I didn’t think I’d make it to Christmas, but now I’m looking forward to celebrating my 50th birthday in July.
Hundreds of staff at four Greater Manchester hospitals to strike AGAIN next week
Emily Sergeant
Another round of strikes has been called at a handful of major Greater Manchester hospitals.
Amid ongoing disputes following the first set of strikes at the end of last month, it has now been announced that more than 350 Northern Care Alliance Foundation Trust (NCA) employees – including nurses, clinical support workers and housekeepers – who are members of the union UNISON will once again walk out for three days next week.
According to the union, the dispute centres on the NCA’s use of an outside agency called NHS Professionals (NHSP) to manage overtime.
When covering staff shortages, workers are entitled to time-and-a-half pay – however in some cases, staff earn less than they would on a normal shift, and some have even been missing out on more than £80 per shift, the union added.
Operating theatre staff were previously on picket lines in June, and although an option to resolve the row was initially tabled by NCA bosses, this has now fallen through.
Hundreds of staff at four of Greater Manchester’s hospitals are set to strike next week / Credit: Stephen Andrews (via Unsplash)
This means that staff at Salford Royal Hospital, Royal Oldham Hospital, Rochdale Infirmary, and Fairfield Hospital in Bury are walking out next week on Monday 14, Tuesday 15, and Thursday 17 September.
The union’s North West regional organiser, Kevin Dolan, said the trust had given ‘no indication’ that it’s willing to re-enter negotiations, adding that operating theatre services were ‘chronically under-staffed’ and staff were choosing to work extra shifts to cover shortages.
Ahead of the August strikes, the trust declared a critical incident to help it secure extra support and keep urgent surgery running, while also announcing that some procedures would have to be postponed.
Understandably, some disruption is expected at each of the hospitals on strike days.
But Gertie Nic Philib, who is the chief people and strategy officer at the Northern Care Alliance, said that the trust will do ‘everything we can to minimise the impact on patients’ and ‘maintain high standards of care and quality at all times.’
“We also have contingency plans in place for emergency situations,” they concluded.
Featured Image – Pxhere
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Stockport man jailed for life after kidnapping and sexually assaulting teenage girl
Emily Sergeant
A Stockport man has been sentenced to life in prison after kidnapping and sexually assaulting a teenage girl on her way home from the library.
Paul Sharpe has been sentenced to life imprisonment with an eight-year minimum term in prison after being convicted of a number of offences when subjected a teenage girl to what police called a ‘terrifying ordeal’ that lasted several hours back in May 2026.
Greater Manchester Police (GMP) confirmed that the victim had been studying at Sale Library before beginning her journey home with friends at around 5:50pm and contacting her parents at 6:10pm to let them know she was on her way.
Twenty minutes later, she spoke to her boyfriend on the phone and said she was approximately five minutes away from home, but that her phone battery was about to die.
This was the last contact received from the victim that evening.
While walking along Bradgate Road in Altrincham, the victim noticed a grey Ford parked nearby and a man wearing a high-visibility jacket pressing doorbells in the area.
As she walked past, Sharpe approached her from behind, placed her in a headlock and threatened to stab her if she did not get into his vehicle.
Concerned that their daughter had not returned home, the victim’s family contacted police at 9:22pm to report her missing, and officers immediately launched an investigation to locate her.
Over the next several hours, the victim was subjected to and placed in a number of terrifying situations.
Sharpe drove the victim to several locations across Greater Manchester and Cheshire, before police located and arrested him at around 3:40am on 19 May 2026.
Following his arrested, 56-year-old Sharpe was convicted of kidnap, committing an offence with intent to commit a sexual offence, sexual assault, engaging in sexual activity in the presence of a child, threats with a bladed article, and administering a noxious substance with intent to injure, annoy or aggrieve.
“This was a terrifying ordeal for a young girl who was simply making her way home,” explained Detective Inspector Karl Perry, from GMP’s Criminal Investigation Department.
“Sharpe targeted a vulnerable victim, subjected her to hours of fear and intimidation, and went on to sexually assault her.
“The victim has shown immense courage throughout the investigation and court proceedings. Through her bravery and actions, she no doubt made it harder for Sharpe to carry out whatever acts he had planned.”
Emily Sergeant -
30th March 2022 
