A clinical trials patient in Manchester is celebrating a new lease of life after having had “a remarkable response” to a new specific gene-targeting treatment that controls how cancer grows.
49-year-old Terri Hurdman, from Bromsgrove in Worcestershire, found out she had advanced bowel cancer on Valentine’s Day two years ago, and didn’t even think she’d make it past Christmas 2021 after finding herself left completely exhausted and out of breath from simple tasks such as climbing the stairs, walking a short distance, or even talking on the phone due to her cancer.
But within hours of trialling a new drug at The Christie NHS Foundation Trust, she was climbing stairs with no effort.
After three months, scans showed her tumours had halved in size.
Terri – who has three children and six grandchildren – was a previously fit and healthy factory worker used to doing manual work for a firm producing medical supplies, and had no symptoms until she got stomach ache and thought it might be IBS – but after having been referred by her GP to Kidderminster hospital, she was diagnosed with stage 4 colorectal cancer, which had spread to her lungs, and started chemotherapy a month later.
After three types of chemotherapy didn’t work, she was told she had no other options and was taken off the drugs.
ADVERTISEMENT
By August 2021, Terri had become very ill, had lost a stone and a half in weight, and was becoming weaker, so she was forced to use a wheelchair to get out and about, but luckily, her consultant at Kidderminster hospital knew The Christie in Manchester was running early phase clinical trials which used targeted therapies – a type of cancer treatment that targets the genes and proteins that control how cancer cells grow and spread – and referred her to see if the trial would be suitable.
Terri is taking part in a new experimental drug trial at The Christie in Manchester / Credit: The Christie NHS Foundation Trust
Terri’s DNA had already been analysed as part of standard NHS testing, and it was found she had a mutation in the KRAS gene of her cancer.
Fortunately, the new international clinical trial was designed specifically for people with the gene mutation that Terri has, so she passed the screening and was recruited onto the trial, and immediately after taking the first dose of the tablets last October, her condition “improved significantly”, specialists at The Christie said.
ADVERTISEMENT
So much so, Terri was able to walk up some stairs without getting out of breath for the first time in months.
“It’s like a miracle. It really is a wonder drug as within days, I didn’t need to use the wheelchair at all, and I didn’t get out of breath climbing stairs, which would have previously led to a coughing fit,” Terri explained.
“That day, I spoke to my sister on the phone for an hour, something that would have wiped me out before, and my appetite came back, which made me look so much healthier, and the colour returned to my cheeks.
“I didn’t think I’d make it to Christmas, but now I’m looking forward to celebrating my 50th birthday in July.
Rudy’s is opening a new pizzeria and pizza school in the former Dawson’s Music site
Georgina Pellant
A year on from the initial news that Rudy’s would be taking over the old Dawson’s Music site on Portland Street, bosses behind the chain of neighbourhood pizzerias have finally hinted towards the new site’s opening date.
Revealing it is set to open in Manchester city centre this spring, they also shared the news that the new 8,000sqft location will be home, not just to another restaurant, but also to Rudy’s very own pizza school.
Billed as a ‘world-class destination for pizzaiolo talent’, the new pizza academy will take just over half the space – providing a structured training programme to both experienced pizza chefs and novices. It is set to welcome over 100 pizza chefs in this first year.
Image: Rudy’s
Image: Rudy’s
The restaurant, meanwhile, will span the rest with room for 120 covers. It will be Rudy’s sixth pizza restaurant in Manchester.
The new location at Portland Street will also be the HQ for Rudy’s Bake at Home, back by popular demand.
Serving the perfect and classic Neapolitan pizza since 2015 from its original Rudy’s in Ancoats, the acclaimed pizzeria has since opened 16 sites across the UK, with the new 120-cover pizzeria in Portland Street being its sixth location in Manchester.
Born out of passion for pizza, Rudy’s follows the authentic Neapolitan tradition of pizza making, serving classic recipes such as Marinara, Margherita and Calabrese – all originating from Naples, the birthplace of pizza.
Rudy’s has been praised by many as one of the best pizzerias in the UK, it is renowned for its consistency and quality in Neapolitan pizza making. On a mission to pave the way in pizza making all accordance to a truly authentic Neapolitan technique, Rudy’s is proud to open Rudy’s Pizza Academy at the new Portland Street location.
Jos Goncalves, manager at Rudy’s Portland Street, said: “We are delighted to announce that our next Rudy’s pizzeria will be located on Manchester’s bustling Portland Street.
Manchester has been home to the Rudy’s famiglia since we first opened in Ancoats in 2015, and we can’t wait to open our latest pizzeria, with the addition of our first Pizza Academy in the city this spring”.
Featured image – Rudy’s
News
Watch as Ed Sheeran debuts new music for the first time ever at ‘intimate’ Manchester gig
Daisy Jackson
Now normally, when an artist chooses to take some brand new material out on tour for the first time, they’ll test the waters with a few intimate shows.
Just recently, we’ve had both Fall Out Boy and Blossoms at Band on the Wall, The 1975 at Gorilla, and Jason Manford in a beer garden.
But for Ed Sheeran, his idea of ‘intimate’ is… the AO Arena. That super cosy 21,000-capacity venue. Ah.
After selling out FOUR nights at the Etihad Stadium last summer, though, the chance to see Ed on stage in an arena again is a novel one, and it sold out the venue in minutes.
The ‘Shape of You’ singer announced this surprise arena tour just weeks before he took to the stage, in support of his upcoming sixth album Subtract.
This mini tour kicked off in Manchester last night – meaning our city got to hear new track ‘Eyes Closed’ live for the first time ever.
You can watch the highlights from Ed Sheeran at the AO Arena in the video below
Ed was supported by TikTok sensation Cian Ducrot, whose flash mob videos have amassed almost 100 million likes.
Cian’s tracks ‘All For You’ and ‘I’ll Be Waiting’ have become chart-topping crowd-pleasers and are already translating well to stages as large as the AO Arena.
Back to the main act, and Ed Sheeran delivers another of his truly impressive solo shows – as always, it’s just him and a loop pedal up on that stage.
It’s a best-of setlist of his most popular (and personal favourite) songs, with some surprises thrown in.
There’s a cover of Lewis Capaldi’s ‘Someone You Loved’, and another of Snoop Dogg’s ‘No Diggity’, that delight the thousands who managed to snap up a ticket for this coveted show.
But it’s Ed’s own songs, especially ‘Bad Habits’, that really light a fire in the audience, sending the entire arena floor in a dancing, sweaty mess.
Introducing his newest song, Ed told the audience: “Right Manchester. Real real danger time. This is danger zone. I’m releasing my brand new single in the morning, it’s called ‘Eyes Closed’.
Ed Sheeran introducing new music in Manchester. Credit: The Manc Group
“I feel so awkward about this album, because I sort of made this album as a therapeutic, cathartic thing, and then I felt better about whatever was going on.”
He added: “This song means a hell of a lot to me, and I’ve never played it live in front of an audience before.
“This gig is about singalongs, and having fun, and feeling one and included and everyone here it’s like a big communal thing. I’m super nervous, so please listen.
“I wrote this song about losing someone… but don’t think about my sh*t, think about your sh*t. This song is for anyone who’s lost anyone. This song is for you.”
With this triumphant return to the live circuit, make no mistake – Ed Sheeran is back.
Emily Sergeant -
30th March 2022 
