Alzheimer’s Research UK has hailed the drug lecanemab as a ‘truly historic moment’ for dementia research after trials found it can slow the rate of decline in people’s memory.
Results from a three-phase clinical trial have been published today by pharmaceutical company Eisai.
The data has shown that the drug can help Alzheimer’s patients over 18 months and help them with day-to-day activities.
The trial included 1,795 people in the early stages of the disease, who received bi-weekly infusions of either lecanemab or a placebo.
Alzheimer’s Research UK has said that the findings represent a ‘major step forward’ for dementia research.
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They noted, however, that lecanemab did come with significant side effects.
Credit: Unsplash
Dr Susan Kohlhaas, Director of Research at Alzheimer’s Research UK, said: “These exciting findings represent a major step forward for dementia research and could herald a new era for people with Alzheimer’s disease. This is the first time a drug has been shown to both reduce the disease in the brain and slow memory decline in clinical trials.
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“Lecanemab works by clearing the amyloid protein that builds up in the brain in people with Alzheimer’s disease. In this trial, the drug slowed down participants’ decline in memory and thinking, and their ability to carry out day-to-day activities. Although the benefits were small and came with significant side effects, it marks the arrival of a treatment that can slow the course of Alzheimer’s disease.
“With all this excitement, there are still many questions and challenges we need to address.
“The treatment window in the trial was for 18 months, so we don’t yet know whether there will be impacts to people that last beyond this. Longer-term studies that are ongoing will tell us whether the modest improvements seen in the trial change the trajectory of the disease longer-term.
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“Lecanemab was associated with severe side effects, and it will be important for regulators to understand the safety profile of the drug before it is given a full license for use.
“The benefits of taking lecanemab in the trial were modest but the challenge and opportunity remains within dementia research to build on these findings into an era where we’re developing multiple treatments against different aspects of Alzheimer’s disease to slow and stop the disease.
“It’s safe to say that the NHS is not ready for a new era of dementia treatment.
“We estimate that unless there are drastic changes in how people access specialist diagnostic tests for Alzheimer’s disease, only 2% of people eligible for drugs like lecanemab will be able to access them. We recommend, through the new Dementia Mission, the government take urgent steps to bring together regulators, industry, clinicians and decision-makers in our health system to put a clear plan in place to ensure people in the UK are among the first in the world to access new treatments once they are licensed.
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“This is truly a historic moment for dementia research. This year is the 30th anniversary of the seminal work that revealed the central role of amyloid protein in Alzheimer’s. The road to an anti-amyloid treatment has been a long one and people with Alzheimer’s have seen many disappointing setbacks.
“We hope that this drug will make it to patients, but it won’t be suitable for everyone with Alzheimer’s, and it’s only a first step on the journey towards a cure.”
Featured image: Unsplash
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Altrincham named one of the UK’s best places to live in 2026 in The Sunday Times’ annual ranking
Emily Sergeant
A popular Greater Manchester town has been named among the UK’s best places to live by the Sunday Times in its annual ranking.
That’s right… it’s that time of year, once again.
The Sunday Times is known for pulling together a list of what it considers to be the most sought-after places to live in the UK every year, and 2026’s ranking has officially been published today – with dozens of locations across the country making up the comprehensive guide, and six of those coveted locations being right here in the North West.
The Sunday Times’s expert judges have visited all locations on the list, and assessed factors such as schools, transport, culture, broadband speeds, access to green spaces, the health of the high streets, and much more to devise the always-talked-about annual ranking.
Macclesfield in Cheshire, Eden Valley in Cumbria, Lancaster in Lancashire, and Aigburth in Liverpool are just some of the North West areas named by the publication in the 2026 list.
Altrincham has been named one of the best places to live in the UK / Credit: The Manc Group
A spotlight has also been shone on two Greater Manchester towns, and one of two has even been given the regional North West title… but which are they?
Where has taken the top spot as the best place to live in the North West for 2026, and is therefore one of the best places to live in the whole of the country? Well, that honour has been given to none other than Greater Manchester’s very-own Altrincham.
The publication described the Trafford town as ‘classy, cool and effortlessly comfortable’.
“Altrincham is a top-notch town brimming with independent businesses and big brands, and now it’s flying even higher,” The Sunday Times said.
The fact that co-working has now arrived on the high street thanks to the conversion of the old Rackhams department store, and that the town’s cultural and creative ‘cachet’ is also on the rise, have been highlighted as reasons as to why Altrincham has been chosen as the North West’s winner, as well its newly-flourishing fitness scene.
Of course, the town has also been praised for its transport links into Manchester city centre and across the region, as well as it being a great place for families thanks to the excellent local schools on offer.
Didsbury was the other Greater Manchester town chosen to represent the best of the North West – with the Manchester suburb described as being ‘stylish, solid, safe, and, yes, a little bit smug in parts… but that’s okay’.
You can read the full Altrincham feature here, and see where else The Sunday Times included in its list for 2026 here.
Featured Image – Geograph
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11 arrested and £70k cash seized during early-morning police drug raids across Greater Manchester
Emily Sergeant
11 people have been arrested, as well as a large amount of cash and drugs seized, during early-morning raids across Greater Manchester.
The raids took place during the early hours of the morning yesterday (Thursday 19 March 2026), where Greater Manchester Police (GMP) successfully executed eight warrants simultaneously across Tameside, Oldham, and Rochdale to tackle a ‘suspected criminal network’ involved in the distribution of class A drugs and firearms.
Officers from Tameside Programme Challenger team, the District Intelligence Unit (DIU), and GMP’s Tactical Aid Unit (TAU) were deployed to each of the addresses.
Following weeks of intelligence gathering and preparation, a total of 11 people – each aged between 24 and 77 – were arrested on suspicion of drug-related offences during the raids.
Eight men and three women were arrested on suspicion of a range of offences, including conspiracy to supply class A and B drugs, being part of an organised crime group, possession with intent to supply, money laundering, and possession of an offensive weapon.
They all remain in police custody for questioning at this time, GMP confirmed.
During searches of the addresses, various class A, B and C drugs – including crack cocaine, heroin, cannabis, and nitrous oxide – were seized, while further recoveries of £70,000 in cash, a zombie knife, a BB gun, and four vehicles were also made at the same time.
Speaking following the success of the raids yesterday, Chief Superintendent Shan Nasim, District Commander for Tameside, said: “[This] operation has been a powerful example of our continued, determined effort to dismantle organised crime in our district and Greater Manchester.
“We have 11 people in custody being questioned by our investigation teams in relation to an organised crime group (OCG) that have been causing widespread harm across our communities.
“This action caused significant disruption of an organised crime group (OCG) and has prevented drugs and weapons from reaching the streets, as well as the associated harms that come hand in hand with organised crime.
“Organised criminals exploit vulnerable people and blight our communities; we will take robust action to catch offenders, keep our communities safe, and protect vulnerable people across Greater Manchester.”
Daisy Jackson -
30th November 2022 
