Researchers are looking for participants to test a potential new treatment for OCD
Volunteers taking part will be reimbursed for their time (including reasonable travel costs) and may be offered the study medication free of charge for 48 weeks.
A leading clinical research organisation is running a clinical trial to test a potential new medication for people living with OCD.
According to the NHS, it is estimated that a quarter of a million people are living with OCD in the UK at some point in their lives, that’s equivalent to 12 in every 1,000.
This number increases drastically when we consider those who haven’t received a diagnosis who could be living with OCD symptoms and not receiving the professional support they may need or understand why they are experiencing intrusive thoughts.
Dr Alex Worthington, Clinical Research Physician at MAC Clinical Research, explains that “obsessive-compulsive disorder, commonly referred to as OCD, is a mental health condition with three main parts: obsessions, emotions, and compulsions.
For #OCDWeek, we wanted to highlight some statistics and information to raise awareness of #OCD.
If you have OCD and are having little to no response to your current antidepressant treatment, you may be eligible to take part in a clinical trial.
“Obsessions are persistent thoughts, images, doubts, worries, or urges that intrude on an individual’s mind, despite being unwanted.
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“These thoughts can cause significant mental discomfort or anxiety. Some of the emotions felt due to intrusive thoughts can include guilt, depression, and disgust.
“Compulsions refer to repetitive behaviours that an individual engages in to temporarily alleviate the anxiety caused by the obsession. Examples of compulsions include checking if a door is locked multiple times or repeating certain phrases mentally.”
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There’s a need for more effective treatment options for OCD, which is why award-winning clinical research organisation, MAC Clinical Research is conducting a clinical trial to test a potential new treatment that is hoped to reduce OCD symptoms and ultimately improve quality of life.
Here at MAC, our OCD clinical trial is open for people struggling with OCD symptoms.
Eligible participants will receive up to £490 plus reasonable travel expenses.
If you or someone you know has been living with OCD or OCD symptoms, and provided you meet the overall criteria, you could be reimbursed up to £490 for your time and participation in the clinical trial plus reasonable travel expenses.
If the treatment works, you may be able to receive nearly a year’s worth (48 weeks) of the medication free of charge as part of an open-label extension study.
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You can find out more and register your interest HERE.
As explained in the summary for this clinical trial, “people with OCD tend to have signalling pathways in the brain which are overactive, causing intrusive thoughts, compulsive behaviour or other OCD symptoms.
“Previous clinical trials suggest that the study medication works to dampen down these overactive pathways which may help people with OCD when used in combination with their usual antidepressant medication.”
The study is expected to run for approximately five months. The trial itself will involve taking the oral medication or a placebo daily for ten weeks alongside seven visits to the clinic for check-ups to examine if your OCD symptoms improve and how well you are coping with taking the medication.
As part of International OCD Awareness Week, MAC also looked intohow the condition affects people in the workplace and answered some of the public’s pressing questions surrounding the disorder with one of the organisation’s leading psychiatrists, Dr David Gregory.
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One of MAC’s leading psychiatrists sheds light on OCD treatment.
To ensure optimal safety, each study participant must meet a pre-determined set of eligibility criteria. To be eligible for the trial, you need to:
Be aged between 18-65
Have had OCD symptoms or an OCD diagnosis for at least 1 year that affects daily life.
Be taking an antidepressant for your OCD that isn’t fully helping.
To ensure optimal patient safety, participants must not have any of the following:
Bipolar, schizophrenia, autism, Tourette’s, or other psychiatric conditions
Diagnosed with an eating disorder.
Have diabetes that requires insulin.
Other criteria will apply.
If you want to learn more about MAC Clinical Research or if you’re considering being part of the clinical trial, you can learn more and register your interest by visiting their OCD research webpage.
For #OCDWeek, we wanted to share what some of our clinical trial participants said made them want to take part in OCD clinical research with MAC.
Featured Image — MAC Clinical Trial/The Manc Group
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MediaCity’s massive Vue cinema has had a comfort upgrade with new ‘Ultra Lux’ seats
Emily Sergeant
Manchester cinephiles are now able to enjoy the latest movie releases in ultimate comfort.
That’s because, over at the popular MediaCity Vue cinema complex, 75 brand-new ‘Ultra Lux’ seats have been installed across seven screens, offering film fans what is, quite literally, the chance to sit in the best seats in the house.
Each seat provides the very-best view of the big screen and comes with a host of premium features.
Some of these exciting premium features include extra-wide armrests and a personal table for snacks and drinks, your very-own beverage cooler, which is ideal for films with a particularly long run-time, and even a back and legs that recline independently, so you can find the most relaxing viewing position possible.
Vue currently has 93 state-of-the-art cinemas throughout the UK and Ireland, totalling more than 850 screens – and the Quayside cinema is the latest to benefit from upgraded seating.
Ultra Lux seats have arrived at Vue Quayside Manchester / Credit: Vue Gallery / Supplied
This means that anyone heading to the cinema to see some of the latest and upcoming releases like Avatar: Fire and Ash, Marty Supreme, The Housemaid, Fackham Hall, Wicked: For Good, and so many more, can experience comfort like never before.
“We have invested in bringing Vue’s best seating option to our venue and are excited for our customers to enhance their experience on their next visit,” commented Darren Tinsley, who is the General Manager at Vue Manchester Quayside.
“It is truly the best way to immerse yourself in a film and to have the most comfortable experience.”
Tickets for Vue Manchester Quayside start from £6.49, with upgrades to Ultra Lux from £3 on selected tickets.
January is a month where the temperatures are colder, the days darker, and the social batteries a little lower, so it couldn’t be a better time to lose yourself in the power of cinema – and treat yourself to an Ultra Lux experience.
You can book tickets to upcoming films online by visiting myvue.com.
Featured Image – Supplied
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A massive home and furniture store just outside of Manchester is holding its biggest ever winter sale
Danny Jones
You heard: a huge home, furniture and accessories store just outside Greater Manchester is holding its biggest ever winter sale, making the festive period and the New Year the perfect time to pop in.
Rather annoyed we got mum those nice cushions for Christmas before we saw this, now, but ah well – there’s always her birthday…
Anyone who’s been to Macclesfield or on a train heading in or out of the North West will have most likely been past this place on the train, but the multi-storey emporium that is Arighi Bianchi really is a must-visit for anyone looking to upgrade their interior on a budget.
The Macclesfield home furnishings store has something for everyone, from high-end luxuries to decorative accessories, with pretty much every price range taken into account – which is why landing some seasonal discounts is such a big win for the region.
A fairly iconic sight as you pass through the Cheshire town, Macclesfield‘s Arighi Bianchi was founded way back in 1854 by two Italian immigrants – both called Antonio – whose surnames give the long-standing retail destination its title.
Well over 170 years later, and it’s more popular than ever, so the bonus of them bringing never-before-seen in-store deductions and special seasonal promotions across all departments is an even bigger win.
It doesn’t matter whether you want to shop online or visit in-store (though we would highly recommend the latter), you can get up to 30% off items in what is their biggest event of 2025.
As well as discounts on everything from sofas, sideboards and dining tables to floors, mattresses and much more, they’re doing cut-price offers on top designer brands from around Europe, including Cattelan Italia, Calligaris, Ercol, Hypnos, Tempur, Vispring and Stressless, just to name a few.
Subject to the usual terms and conditions, customers can even get early flexible finance deals (24 months 0% APR*) on their purchases; after all, they know as well as we do how tight money can be around this time of year.
Better still, their early bird offers, which are on top of the standard winter sale, will see even more cost cuttings on the likes of the Britannia Sofa, Freja Dining Bundle, the Heritage Bed Collection and other premium accessories from 27 December until 18 January.
For instance, if you spend £1,200 in-store, you will receive an extra £50 voucher for the CASA Accessories Lounge; or, beyond that, spend £2.5k and earn yourself a £100 voucher.
So, if you’re looking to get a fresh living room suite for 2026, make the most of 10% off wallpaper and fabrics or 20% off mirrors, or even get four new dining chairs for the price of three, there’s a cheeky deal to suit just about everyone.
You can see the full extent of what’s on offer during the Arighi Bianchi winter sale right HERE, or go and peruse the four floors for yourself in the flesh on the famous Silk Road.
Happy holiday season shopping, folks – maybe bump into you around Caffè AB.
Danny Jones -
16th November 2023 
