Researchers are looking for participants to test a potential new treatment for OCD
Volunteers taking part will be reimbursed for their time (including reasonable travel costs) and may be offered the study medication free of charge for 48 weeks.
A leading clinical research organisation is running a clinical trial to test a potential new medication for people living with OCD.
According to the NHS, it is estimated that a quarter of a million people are living with OCD in the UK at some point in their lives, that’s equivalent to 12 in every 1,000.
This number increases drastically when we consider those who haven’t received a diagnosis who could be living with OCD symptoms and not receiving the professional support they may need or understand why they are experiencing intrusive thoughts.
Dr Alex Worthington, Clinical Research Physician at MAC Clinical Research, explains that “obsessive-compulsive disorder, commonly referred to as OCD, is a mental health condition with three main parts: obsessions, emotions, and compulsions.
For #OCDWeek, we wanted to highlight some statistics and information to raise awareness of #OCD.
If you have OCD and are having little to no response to your current antidepressant treatment, you may be eligible to take part in a clinical trial.
“Obsessions are persistent thoughts, images, doubts, worries, or urges that intrude on an individual’s mind, despite being unwanted.
ADVERTISEMENT
“These thoughts can cause significant mental discomfort or anxiety. Some of the emotions felt due to intrusive thoughts can include guilt, depression, and disgust.
“Compulsions refer to repetitive behaviours that an individual engages in to temporarily alleviate the anxiety caused by the obsession. Examples of compulsions include checking if a door is locked multiple times or repeating certain phrases mentally.”
ADVERTISEMENT
There’s a need for more effective treatment options for OCD, which is why award-winning clinical research organisation, MAC Clinical Research is conducting a clinical trial to test a potential new treatment that is hoped to reduce OCD symptoms and ultimately improve quality of life.
Here at MAC, our OCD clinical trial is open for people struggling with OCD symptoms.
Eligible participants will receive up to £490 plus reasonable travel expenses.
If you or someone you know has been living with OCD or OCD symptoms, and provided you meet the overall criteria, you could be reimbursed up to £490 for your time and participation in the clinical trial plus reasonable travel expenses.
If the treatment works, you may be able to receive nearly a year’s worth (48 weeks) of the medication free of charge as part of an open-label extension study.
ADVERTISEMENT
You can find out more and register your interest HERE.
As explained in the summary for this clinical trial, “people with OCD tend to have signalling pathways in the brain which are overactive, causing intrusive thoughts, compulsive behaviour or other OCD symptoms.
“Previous clinical trials suggest that the study medication works to dampen down these overactive pathways which may help people with OCD when used in combination with their usual antidepressant medication.”
The study is expected to run for approximately five months. The trial itself will involve taking the oral medication or a placebo daily for ten weeks alongside seven visits to the clinic for check-ups to examine if your OCD symptoms improve and how well you are coping with taking the medication.
As part of International OCD Awareness Week, MAC also looked intohow the condition affects people in the workplace and answered some of the public’s pressing questions surrounding the disorder with one of the organisation’s leading psychiatrists, Dr David Gregory.
ADVERTISEMENT
One of MAC’s leading psychiatrists sheds light on OCD treatment.
To ensure optimal safety, each study participant must meet a pre-determined set of eligibility criteria. To be eligible for the trial, you need to:
Be aged between 18-65
Have had OCD symptoms or an OCD diagnosis for at least 1 year that affects daily life.
Be taking an antidepressant for your OCD that isn’t fully helping.
To ensure optimal patient safety, participants must not have any of the following:
Bipolar, schizophrenia, autism, Tourette’s, or other psychiatric conditions
Diagnosed with an eating disorder.
Have diabetes that requires insulin.
Other criteria will apply.
If you want to learn more about MAC Clinical Research or if you’re considering being part of the clinical trial, you can learn more and register your interest by visiting their OCD research webpage.
For #OCDWeek, we wanted to share what some of our clinical trial participants said made them want to take part in OCD clinical research with MAC.
Featured Image — MAC Clinical Trial/The Manc Group
Sponsored
The Manchester restaurant serving up the ‘world’s hottest curry’ for just a few days
Danny Jones
City centre favourite Zouk is serving up ‘the world’s hottest curry’ again to celebrate National Chilli Day next week.
The popular tea bar and grill located on Chester Street just off Oxford Road is slap bang in the middle of student central and has hordes of patrons lining up day in, day out, to taste their incredible Indian and Pakistani cuisine.
Now, to celebrate every spicy-food lover’s favourite day, Zouk is putting on special, limited-time-only menu to cater to all you heat freaks and speaking collectively on The Manc‘s behalf (several of us having tried it), it’s no joke.
The World’s Hottest Curry will be available for five days from Monday 24 to Friday 28 February, with a challenge on Thursday 27 February with prizes to anyone who can finish the fiery karahi.
The dishes
When it came to coming up with the world’s hottest curry, Zouk didn’t have to look far for inspiration, they simply picked the world’s hottest chilli: the Carolina Reaper Chilli.
Combining the 1,569,000 Scoville scorcher of a chilli with their much-loved and already spicy chicken karahi and vegetable karahi recipes, they knew they were on a winner. You might have to sign a waiver to eat it but that’s all part of the fun, right?
Typically prepared in a wok and cooked over hot flames with tomatoes, ginger, garlic, peppercorns and cumin to create the sauce base, the karahi originates from the Northwest region of Pakistan and has a great flavour. Depending on how brave you’re feeling, you can have it as a kebab or a full curry.
Credit: Supplied
That being said, this version does contain dried Carolina Reapers so you might not taste much beyond the heat of the sun after a few seconds. While the chilli is deemed suitable for human consumption, even Zouk’s chefs have admitted to struggling with the dish. Gulp. So, what can you win?
The challenge and prizes
Us Brits love a good curry and we already know that plenty of you won’t be able to resist the urge to take on the Reaper Challenge simply out of pride, so we might as well just tell you what you’ll have to eat in order to win the prizes.
Here’s what’s up for grabs:
Finish the full Carolina Reaper Curry (either chicken or veg) in one sitting (max eating time 30 minutes and no helping from companions), Zouk will give you the meal for free.
PLUS, a £50 Zouk Gift Card so you can come back at a later date to try their full menu (including some less omg-spicy options).
You’ll also get a Zouk Ice Cream Sunday to help cool off afterwards. Trust us, you’ll need it.
Issuing a statement for National Chilli Day and the Reaper Challenge, owner Tayub Amjad said: “Our food is usually more about flavour than heat but it’s National Chilli Day, and we know our customers love this challenge.
“For those who complete the challenge, you still have chance to come back and dine on us at a future date, so you will still get to experience the real Zouk too.”
What you thinking, Manchester? Are you up for taking on the world’s hottest curry?
Grammy-winning disco legend Purple Disco Machine is heading to Manchester for a huge gig
Daisy Jackson
Legendary German nu-disco and house producer Purple Disco Machine has a huge Manchester gig on the horizon, hot off the back of the release of his Paradise album.
The Grammy Award-winning artist’s latest release is packed with collaborations from some of the biggest names in music, including Nile Rodgers, Metronomy, Jake Shears, Duke Dumont, Sophie and the Giants, Nothing But Thieves and more.
And now he’s bringing his unforgettable disco vibes to a dance floor on our home turf, with a massive gig lined up at O2 Victoria Warehouse.
Set to take place on Friday 7 March, Purple Disco Machine will promise an incredible night of sizzling dance and house music, with support from Dan Shake, Oden & Fatzo Live!, and Urbi.
His irresistible sound includes hits like Hypnotised, Dished (Male Stripper) and, never one to miss a trend, an addictive remix of I’m Just Ken from the Barbie soundtrack.
His other remixes have included tracks for Dua Lipa, Sir Elton John, Mark Ronson, Calvin Harris, Fatboy Slim and Britney Spears.
And of course there’s that Grammy win for his remix of Lizzo’s About Damn Time.
On Paradise, he’s released tonnes more addictive disco beats, notably Substitution with Julian Perretta, and Honey Boy with Nile Rodgers.
And live, Purple Disco Machine has cut his teeth on the British festival circuit, including recently joining Fisher at his headline Gunnersbury Park show in London.
Now a multi-platinum-selling artist, with more than two billion streams worldwide, the Paradise tour is set to take Manchester by storm.
Purple Disco Machine will be at the O2 Victoria Warehouse in Manchester on Friday 7 March – you can get tickets HERE.
Danny Jones -
16th November 2023 
