Researchers are looking for participants to test a potential new treatment for OCD
Volunteers taking part will be reimbursed for their time (including reasonable travel costs) and may be offered the study medication free of charge for 48 weeks.
A leading clinical research organisation is running a clinical trial to test a potential new medication for people living with OCD.
According to the NHS, it is estimated that a quarter of a million people are living with OCD in the UK at some point in their lives, that’s equivalent to 12 in every 1,000.
This number increases drastically when we consider those who haven’t received a diagnosis who could be living with OCD symptoms and not receiving the professional support they may need or understand why they are experiencing intrusive thoughts.
Dr Alex Worthington, Clinical Research Physician at MAC Clinical Research, explains that “obsessive-compulsive disorder, commonly referred to as OCD, is a mental health condition with three main parts: obsessions, emotions, and compulsions.
For #OCDWeek, we wanted to highlight some statistics and information to raise awareness of #OCD.
If you have OCD and are having little to no response to your current antidepressant treatment, you may be eligible to take part in a clinical trial.
“Obsessions are persistent thoughts, images, doubts, worries, or urges that intrude on an individual’s mind, despite being unwanted.
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“These thoughts can cause significant mental discomfort or anxiety. Some of the emotions felt due to intrusive thoughts can include guilt, depression, and disgust.
“Compulsions refer to repetitive behaviours that an individual engages in to temporarily alleviate the anxiety caused by the obsession. Examples of compulsions include checking if a door is locked multiple times or repeating certain phrases mentally.”
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There’s a need for more effective treatment options for OCD, which is why award-winning clinical research organisation, MAC Clinical Research is conducting a clinical trial to test a potential new treatment that is hoped to reduce OCD symptoms and ultimately improve quality of life.
Here at MAC, our OCD clinical trial is open for people struggling with OCD symptoms.
Eligible participants will receive up to £490 plus reasonable travel expenses.
If you or someone you know has been living with OCD or OCD symptoms, and provided you meet the overall criteria, you could be reimbursed up to £490 for your time and participation in the clinical trial plus reasonable travel expenses.
If the treatment works, you may be able to receive nearly a year’s worth (48 weeks) of the medication free of charge as part of an open-label extension study.
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You can find out more and register your interest HERE.
As explained in the summary for this clinical trial, “people with OCD tend to have signalling pathways in the brain which are overactive, causing intrusive thoughts, compulsive behaviour or other OCD symptoms.
“Previous clinical trials suggest that the study medication works to dampen down these overactive pathways which may help people with OCD when used in combination with their usual antidepressant medication.”
The study is expected to run for approximately five months. The trial itself will involve taking the oral medication or a placebo daily for ten weeks alongside seven visits to the clinic for check-ups to examine if your OCD symptoms improve and how well you are coping with taking the medication.
As part of International OCD Awareness Week, MAC also looked intohow the condition affects people in the workplace and answered some of the public’s pressing questions surrounding the disorder with one of the organisation’s leading psychiatrists, Dr David Gregory.
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One of MAC’s leading psychiatrists sheds light on OCD treatment.
To ensure optimal safety, each study participant must meet a pre-determined set of eligibility criteria. To be eligible for the trial, you need to:
Be aged between 18-65
Have had OCD symptoms or an OCD diagnosis for at least 1 year that affects daily life.
Be taking an antidepressant for your OCD that isn’t fully helping.
To ensure optimal patient safety, participants must not have any of the following:
Bipolar, schizophrenia, autism, Tourette’s, or other psychiatric conditions
Diagnosed with an eating disorder.
Have diabetes that requires insulin.
Other criteria will apply.
If you want to learn more about MAC Clinical Research or if you’re considering being part of the clinical trial, you can learn more and register your interest by visiting their OCD research webpage.
For #OCDWeek, we wanted to share what some of our clinical trial participants said made them want to take part in OCD clinical research with MAC.
Featured Image — MAC Clinical Trial/The Manc Group
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Manchester’s historic connections to slavery will be at the heart of a major new exhibition
Emily Sergeant
Manchester’s historic connections to slavery are to be explored during a major new exhibition coming soon to the city.
The Science and Industry Museum, in the heart of our city centre, is already known and loved for telling the story of the ideas and innovations that transformed Manchester into the world’s first industrial city.
But now, a new free exhibition is set to “enhance public understanding” of how transatlantic slavery actually shaped the city’s growth.
Produced by the Science and Industry Museum, in partnership with The Scott Trust Legacies of Enslavement programme, and developed with African descendent and diaspora communities through local and global collaborations, this landmark project will put Manchester’s historic connections to enslavement at the heart of a major exhibition at the museum for the first time.
Featuring new research, it will also explore how the legacies of these histories continue to impact Manchester, the world, and lives today.
Set to open in early 2027, the exhibition will run for a year in the museum’s Special Exhibitions Gallery.
Alongside that hub at the Science and Industry Museum itself, the project is also set to have a collaborative city-wide events programme, and a lasting legacy – with a new permanent schools programme, and permanent displays in the future too.
As mentioned, the new exhibition is part of The Scott Trust Legacies of Enslavement programme, which is a 10-year restorative justice project launched in 2023.
Manchester’s historic connections to slavery will be at the heart of a major new exhibition / Credit: Science Museum Group Collection
Through partnerships and community programmes, the project aims to improve public understanding of the impact of transatlantic slavery on the UK’s economic development, and its ongoing legacies for Black communities – with a strong focus on Manchester, the city in which The Guardian was founded back in 1821.
The museum’s existing gallery content and ongoing work around sharing the inextricable links between Manchester’s growth into an industrial powerhouse and a textile industry reliant on colonialism and enslavement will be developed through the project.
Through a “collaborative re-examination of the past”, the exhibition will also share a more inclusive history of a city that prides itself on being at the forefront of ideas that change the world.
It’s opening at the Science and Industry Museum in early 2027 / Credit: Science and Industry Museum
Speaking ahead of the exhibition’s arrival in early 2027, Sally MacDonald, who is the Director of the Science and Industry Museum, says: “This will be an exhibition about important aspects of our past that are profoundly relevant to the world we live in today.
“Revealed from the perspectives of those who experienced enslavement and whose lives have been shaped by its legacies, we will foreground stories of resistance, agency, and skill.
“The exhibition will explore themes of resilience, identity and creativity alongside exploitation and inequality, and will feature a specific focus on the ways that scientific and technological developments both drove and were driven by transatlantic slavery.”
Further details on the project will be announced in due course, so stay tuned.
Featured Image – Science Museum Group
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Charlotte Dawson will be handing out compliments and big prizes in Manchester to brighten Blue Monday
Daisy Jackson
TV star Charlotte Dawson will be cheering up Blue Monday in Manchester, dishing out compliments to strangers and awarding some big prizes too.
The actress, who is the daughter of the legendary late Les Dawson, will be bringing her signature sunny energy to Printworks on Monday 20 January.
Otherwise known as Blue Monday, it’s believed that the third Monday in January is the most depressing day of the year – so she’s here to nip that in the bud.
Between 1pm and 3pm on the huge gaming screen inside Printworks – part of its £21m transformation that included adding a huge digital ceiling – Charlotte Dawson will be spreading joy and laughter.
She’ll be live streaming straight to passers-by, spreading smiles and dishing out compliments.
Charlotte will also be treating visitors to some amazing prizes from Printworks’ collection of bars, restaurants and leisure venues.
These prizes will include free brunch for four at Walkabout, gaming sessions at Bierkeller, or family cinema tickets with Ice Blasts at VUE. Other prizes include Nando’s vouchers, a drink and activity for two at the new Trax Social, and much more.
And the top prize will be a luxury overnight stay for two at Hotel Indigo, just across the road in the very heart of Manchester.
Charlotte Dawson will take part in Blue Monday at Printworks, Manchester
There’ll even be free coffee vouchers for Todd St Cafe on offer to brighten your Blue Monday.
Kristian Brennan, Marketing Manager at Printworks, said: “We couldn’t be more excited to have Charlotte at Printworks this Blue Monday.
“As a true Mancunian icon, her vibrant personality is exactly what we need to brighten up the most depressing day of the year and we know she’ll bring plenty of laughs and smiles to everyone who stops by.
“What makes this event truly unique is the opportunity for the public to chat with Charlotte under Europe’s largest digital ceiling, which will showcase new mood-boosting content.
“It’s an innovative and exciting way for people to connect, and we can’t wait to see families and friends come together to create joyful memories in this truly unique setting!”
Danny Jones -
16th November 2023 
