Researchers are looking for participants to test a potential new treatment for OCD
Volunteers taking part will be reimbursed for their time (including reasonable travel costs) and may be offered the study medication free of charge for 48 weeks.
A leading clinical research organisation is running a clinical trial to test a potential new medication for people living with OCD.
According to the NHS, it is estimated that a quarter of a million people are living with OCD in the UK at some point in their lives, that’s equivalent to 12 in every 1,000.
This number increases drastically when we consider those who haven’t received a diagnosis who could be living with OCD symptoms and not receiving the professional support they may need or understand why they are experiencing intrusive thoughts.
Dr Alex Worthington, Clinical Research Physician at MAC Clinical Research, explains that “obsessive-compulsive disorder, commonly referred to as OCD, is a mental health condition with three main parts: obsessions, emotions, and compulsions.
For #OCDWeek, we wanted to highlight some statistics and information to raise awareness of #OCD.
If you have OCD and are having little to no response to your current antidepressant treatment, you may be eligible to take part in a clinical trial.
“Obsessions are persistent thoughts, images, doubts, worries, or urges that intrude on an individual’s mind, despite being unwanted.
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“These thoughts can cause significant mental discomfort or anxiety. Some of the emotions felt due to intrusive thoughts can include guilt, depression, and disgust.
“Compulsions refer to repetitive behaviours that an individual engages in to temporarily alleviate the anxiety caused by the obsession. Examples of compulsions include checking if a door is locked multiple times or repeating certain phrases mentally.”
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There’s a need for more effective treatment options for OCD, which is why award-winning clinical research organisation, MAC Clinical Research is conducting a clinical trial to test a potential new treatment that is hoped to reduce OCD symptoms and ultimately improve quality of life.
Here at MAC, our OCD clinical trial is open for people struggling with OCD symptoms.
Eligible participants will receive up to £490 plus reasonable travel expenses.
If you or someone you know has been living with OCD or OCD symptoms, and provided you meet the overall criteria, you could be reimbursed up to £490 for your time and participation in the clinical trial plus reasonable travel expenses.
If the treatment works, you may be able to receive nearly a year’s worth (48 weeks) of the medication free of charge as part of an open-label extension study.
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You can find out more and register your interest HERE.
As explained in the summary for this clinical trial, “people with OCD tend to have signalling pathways in the brain which are overactive, causing intrusive thoughts, compulsive behaviour or other OCD symptoms.
“Previous clinical trials suggest that the study medication works to dampen down these overactive pathways which may help people with OCD when used in combination with their usual antidepressant medication.”
The study is expected to run for approximately five months. The trial itself will involve taking the oral medication or a placebo daily for ten weeks alongside seven visits to the clinic for check-ups to examine if your OCD symptoms improve and how well you are coping with taking the medication.
As part of International OCD Awareness Week, MAC also looked intohow the condition affects people in the workplace and answered some of the public’s pressing questions surrounding the disorder with one of the organisation’s leading psychiatrists, Dr David Gregory.
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One of MAC’s leading psychiatrists sheds light on OCD treatment.
To ensure optimal safety, each study participant must meet a pre-determined set of eligibility criteria. To be eligible for the trial, you need to:
Be aged between 18-65
Have had OCD symptoms or an OCD diagnosis for at least 1 year that affects daily life.
Be taking an antidepressant for your OCD that isn’t fully helping.
To ensure optimal patient safety, participants must not have any of the following:
Bipolar, schizophrenia, autism, Tourette’s, or other psychiatric conditions
Diagnosed with an eating disorder.
Have diabetes that requires insulin.
Other criteria will apply.
If you want to learn more about MAC Clinical Research or if you’re considering being part of the clinical trial, you can learn more and register your interest by visiting their OCD research webpage.
For #OCDWeek, we wanted to share what some of our clinical trial participants said made them want to take part in OCD clinical research with MAC.
Featured Image — MAC Clinical Trial/The Manc Group
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You can get a mobile massage treatment in your office – just like us
Thomas Melia
We’d like to introduce you to the pioneering personalised service offering massage treatments on the move at practically any location including direct from your office– including to those of us here in Manchester.
In a world where you can get practically anything delivered straight to your door, it wasn’t going to be long until some genius invented a way to get a massage from the comfort of your own office.
Named ‘London’s first digital beauty concierge’, Ruuby have been pampering the nation’s capital for almost a decade before branching out to further locations.
The gorgeous set up provided by RuubyLook at that lovely branding on the towels.They did wonders with our otherwise plain downstairs office space. (Credit: The Manc Group)
In October 2024, the company expanded beyond its domestic reach in the likes of the capital, the Cotswolds and Surrey into Europe, making its first mark Switzerland: the perfect country for both luxury and essential beauty treatments with a tailored experience.
The month following saw the group moving up North and all the way to Manchester, where people can now book professional treatments best suited to them, right on their doorstep.
If you’re feeling scepticalstill, you can take it from us here at The Manc; we couldn’t tell you how relaxing and comforting these massages are.
There are a range of treatments available and we opted for two bespoke massages, a sports massage and a deep tissue massage.
Each experience is suited to your personal needs meaning each massage therapist will be able to fine-tune their relaxation abilities to what benefits you best.
After choosing the bespoke massage that I felt would work best for me, I went into this with no prior massage experience and I came out feeling taller, broader and more refreshed. Highly recommend.
Mid-day office massage? Yes, please.How relaxing. What a shame you have to go back to work after!Credit: The Manc Group
My masseuse guided me throughout the whole process and we soon discovered that I was able to tolerate much harder pressure than I thought which helped release tension I didn’t even know I had!
The same applies to how firm you’d like your session to be, as the masseuse can help with a brief overview of your time together, but the amount of pressure you like is down to personal preference.
It’s not just massages either: there’s everything from waxing, nails and hair to physio and IV drips; how about getting Marbella ready in less than an hour with a spray tan service set up wherever you are?
As Ruuby is a mobile and remote work environment, there are a number of at any time up and down the country, meaning your next beauty slot could be as little as an hour away, find out more HERE.
An award-winning Manchester cocktail bar is serving a Tiny ‘Tini martini cocktail flight
Daisy Jackson
Martini cocktails are one of the world’s most iconic and stylish cocktails, and come in a lot of different shapes and sizes, despite classically being made with only a few ingredients.
If you’re still dipping your toes into the world of the vodka martini cocktail, or if you’re a super fan always eager to try a new take on this beloved drink, can we introduce you to the ‘Tiny ‘Tini’ flight?
This clever creation is as photo-worthy as it is delicious – three miniature martini cocktails, served perfectly chilled in ‘flight’ form on a tray in one of Manchester’s very best bars, Blinker.
The Tiny ‘Tini has been launched by legendary vodka brand GREY GOOSE to celebrate the resurgence of vodka martini cocktails (vodka is one of the core ingredients, the other is typically vermouth).
Blinker, which was earlier this year named the 22nd best cocktail bar in the UK, is already famed for its menu of vodka martini cocktails , so was a perfect choice for the GREY GOOSE Tiny ‘Tini collaboration.
Here, they’ve created three different miniature takes on the classic cocktail- the house martini cocktail, made with GREY GOOSE vodka, house vermouth, orange bitters and an olive; the Spanish Gibson, with sherry and onion brine (if you’re a fan of savoury cocktails, this is the one for you); and the champagne martini cocktail, with GREY GOOSE vodka, champagne cordial, Lillet Blanc and orange bitters (a gateway martini cocktail for the uninitiated).
Each of the three perfectly sized drinks is served in a special frosted miniature martini cocktail glass and is the perfect size for flavour exploration – while also staying perfectly chilled down to the last sip.
The Grey Goose Tiny Tini martini cocktail flight is available at Blinker in Manchester
Best of all, the Tiny ‘Tini flight also makes vodka martini cocktails that little bit less intimidating.
Lexa Ulijaszek, UK Ambassador for GREY GOOSE commented: “When it comes to the vodka martini cocktail, size does matter for some.
“Sometimes a full-sized martini cocktail can be a little bit too intimidating. Or over the course of great conversation between friends, the final sip of your drink may not be as superbly chilled or balanced in taste as the beginning.
“As a result, the offer of a ‘sip sized cocktail’ is gaining traction across many of the UK’s most influential bars.
“A sip size GREY GOOSE Tiny ‘Tini is the perfect solution – beautifully crafted, expertly chilled, elegantly served with rich taste. A flight of three petite drinks allows you to responsibly enjoy the perfection of the ‘first sip’ of a martini cocktail while also experiencing a range of unique flavours.
“The trend is very much a UK-wide affair, with some of the best bars across Manchester, Edinburgh and London all serving the GREY GOOSE Tiny ‘Tini – ushering in a brand new and bold ‘sip sized’ era for the vodka martini cocktail.”
The GREY GOOSE Tiny ‘Tini flight at Blinker in Manchester costs £12 and is available until 30 April.
Danny Jones -
16th November 2023 
