Researchers are looking for participants to test a potential new treatment for OCD
Volunteers taking part will be reimbursed for their time (including reasonable travel costs) and may be offered the study medication free of charge for 48 weeks.
A leading clinical research organisation is running a clinical trial to test a potential new medication for people living with OCD.
According to the NHS, it is estimated that a quarter of a million people are living with OCD in the UK at some point in their lives, that’s equivalent to 12 in every 1,000.
This number increases drastically when we consider those who haven’t received a diagnosis who could be living with OCD symptoms and not receiving the professional support they may need or understand why they are experiencing intrusive thoughts.
Dr Alex Worthington, Clinical Research Physician at MAC Clinical Research, explains that “obsessive-compulsive disorder, commonly referred to as OCD, is a mental health condition with three main parts: obsessions, emotions, and compulsions.
For #OCDWeek, we wanted to highlight some statistics and information to raise awareness of #OCD.
If you have OCD and are having little to no response to your current antidepressant treatment, you may be eligible to take part in a clinical trial.
“Obsessions are persistent thoughts, images, doubts, worries, or urges that intrude on an individual’s mind, despite being unwanted.
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“These thoughts can cause significant mental discomfort or anxiety. Some of the emotions felt due to intrusive thoughts can include guilt, depression, and disgust.
“Compulsions refer to repetitive behaviours that an individual engages in to temporarily alleviate the anxiety caused by the obsession. Examples of compulsions include checking if a door is locked multiple times or repeating certain phrases mentally.”
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There’s a need for more effective treatment options for OCD, which is why award-winning clinical research organisation, MAC Clinical Research is conducting a clinical trial to test a potential new treatment that is hoped to reduce OCD symptoms and ultimately improve quality of life.
Here at MAC, our OCD clinical trial is open for people struggling with OCD symptoms.
Eligible participants will receive up to £490 plus reasonable travel expenses.
If you or someone you know has been living with OCD or OCD symptoms, and provided you meet the overall criteria, you could be reimbursed up to £490 for your time and participation in the clinical trial plus reasonable travel expenses.
If the treatment works, you may be able to receive nearly a year’s worth (48 weeks) of the medication free of charge as part of an open-label extension study.
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You can find out more and register your interest HERE.
As explained in the summary for this clinical trial, “people with OCD tend to have signalling pathways in the brain which are overactive, causing intrusive thoughts, compulsive behaviour or other OCD symptoms.
“Previous clinical trials suggest that the study medication works to dampen down these overactive pathways which may help people with OCD when used in combination with their usual antidepressant medication.”
The study is expected to run for approximately five months. The trial itself will involve taking the oral medication or a placebo daily for ten weeks alongside seven visits to the clinic for check-ups to examine if your OCD symptoms improve and how well you are coping with taking the medication.
As part of International OCD Awareness Week, MAC also looked intohow the condition affects people in the workplace and answered some of the public’s pressing questions surrounding the disorder with one of the organisation’s leading psychiatrists, Dr David Gregory.
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One of MAC’s leading psychiatrists sheds light on OCD treatment.
To ensure optimal safety, each study participant must meet a pre-determined set of eligibility criteria. To be eligible for the trial, you need to:
Be aged between 18-65
Have had OCD symptoms or an OCD diagnosis for at least 1 year that affects daily life.
Be taking an antidepressant for your OCD that isn’t fully helping.
To ensure optimal patient safety, participants must not have any of the following:
Bipolar, schizophrenia, autism, Tourette’s, or other psychiatric conditions
Diagnosed with an eating disorder.
Have diabetes that requires insulin.
Other criteria will apply.
If you want to learn more about MAC Clinical Research or if you’re considering being part of the clinical trial, you can learn more and register your interest by visiting their OCD research webpage.
For #OCDWeek, we wanted to share what some of our clinical trial participants said made them want to take part in OCD clinical research with MAC.
Featured Image — MAC Clinical Trial/The Manc Group
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A dedicated anime, movie and gaming concert with a live orchestra is coming to Manchester
Danny Jones
Calling all self-proclaimed otakus, cinephiles and gamers: a huge concert experience will see dozens of musicians bring classic anime, film and gaming soundtracks and scores to life later this year, right here in Manchester.
The city is no stranger to events celebrating these beloved kinds of media, but you’ll struggle to find another bringing all of them together in one place.
Brought to us Mancs by KIN Music Entertainment, a locally founded arts, events and music label, this celebration of all things pop culture – and specifically, the music tied to it.
Entitled ‘The Kin & Fushigi Anime, Film & Videogame Orchestra’, this passionate collective serves as not only a platform for rising artists but also to hear some iconic sonic moments like never before.
KIN have created a large-scale live concert experience which will bring together a 25-piece pop orchestra made up of emerging professional performers and conservatoire graduates.
Aside from the impressive total of people behind this production to begin with, they also form an immersive hybrid orchestral and live band capable of bringing.
Speaking on the upcoming date, KIN Entertainment said in a statement: “We wanted to create the kind of live experience that many anime and videogame fans in Manchester have been waiting for — something cinematic, emotional and community-driven that brings these sound worlds to life with the energy of both an orchestra and a live band.”
Kin was founded by bassist, composer and ensemble performer Alejandro Urbina Diaz, who first brought his talents and wider interests over from Mexico to the Royal Northern College of Music (RNCM) here in the city centre at the age of 23.
Citing Manchester’s multiculturalism and cosmopolitan cultural fabric as a big part of his inspiration, he and his team have ended up carving out this niche for themselves, and now they’ll be playing this beloved music to Mancs at none other than the O2 Ritz.
Credit: KIN Music Entertainment (supplied via Academy Music Group Digital)
With new arrangements inspired by anime, cinematic and videogame culture, not to mention orchestral and even rock crossover twists – including both vocalist and rhythm sections, by the way – it’s set to be a highly unique experience that most will have never come across before.
This event itself is suitable for audiences aged 14+, although under-16s must be accompanied by an adult, and it’s taking place at the Ritz on Sunday, 26 July.
We’re not going to spoil any more details about the show for you, so which particular pieces of pop culture they reference will just have to be a surprise…
Featured Images — Publicity pictures (supplied via AMG Digital)
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You can now get Deep South-inspired BBQ dishes on Manchester’s Deansgate
Daisy Jackson
There’s a brand-new menu of smokehouse-style BBQ dishes being served up on a sunny terrace on Deansgate.
Motley, the neighbourhood bar and restaurant on the corner of John Dalton Street, has added an authentic smoker to its kitchen.
That means they’ve got a whole load of new dishes, slow-cooked over hickory wood, that are bringing a taste of a Deep South BBQ to Manchester city centre.
The smokehouse-style meats are all seasoned in-house and cooked for hours, for a perfect fall-off-the-bone experience.
It might be an authentic American smokehouse menu, but it’s firmly British too, with most products locally sourced.
You can now get Deep South-inspired BBQ dishes on Deansgate / Credit: The Manc Group
Motley are calling on local suppliers like Althams Butchers (established since 1856) for their meat, plus greengrocers R Noone and Son, and Cheshire Farm for their real dairy ice cream.
Signature dishes on the new menu at Motley include slow smoked brisket, seasoned in Motley’s signature rub before being slow-smoked for more than eight hours.
There’s also a beef short rib with a chimichurri sauce, and a pork belly strip that’s seasoned with sage and onion and finished with a panko breadcrumb crust.
And for the veggies, there’s a vegan smoked veg kebab with courgette, mushrooms, bell pepper, sweet corn and red onion drizzled with homemade BBQ sauce.
Motley has added an authentic smoker to its kitchen / Credit: The Manc Group
Prices across the board start from just £16, served with beef dripping fries, rainbow slaw, pickles and homemade beef gravy.
As for small plates, you can expect short rib bonbons, homemade corn bread, spicy chicken wings, bang bang cauliflower, mac and cheese, and frickles.
House favourites like steak, vegetable hash, salads, and burgers will remain on the Motley menu.
Victor Gonzalez, food and beverage manager at Motley, said: “Our new signature smoked dishes are all crafted and seasoned in-house then slow cooked for hours over hickory wood to create rich and smoky melt-in-your mouth flavours.
“From our slow-smoked brisket to our home-made sides, everything has been carefully crafted to bring an authentic taste of the deep south to Manchester and we can’t wait for guests to try it.”
Motley can be found at 2 John Dalton Street on the corner of Deansgate in the city centre.
Danny Jones -
16th November 2023 
