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Groundbreaking treatment to be given to children with peanut allergies in the UK

Emily Sergeant Emily Sergeant - 23rd December 2021

NHS England has secured a new deal which means that children with peanut allergies in the UK will be the first to receive a groundbreaking new treatment.

The oral treatment – named Palforzia – decreases the severity of symptoms brought on by peanut allergies, including the potentially life-threatening allergic reaction known as anaphylaxis, and will soon be available to up to 600 children aged four to 17 the first year, and 2,000 the following year, thanks to the new deal.

The deal has been secured after Evelina London Children’s Hospital took part in two large peanut allergy trials – the Palisade and Artemis studies.

Both trials are said to have transformed the lives of some of its participants.

“This pioneering treatment can be life-changing for patients and their families and, thanks to the deal the NHS has struck, people here will be the first in Europe to benefit,” explained NHS Medical Director, Professor Stephen Powis.

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“It will reduce the fear and anxiety for patients and their families who may have been living with this allergy for years.

“And carrying around emergency medication just in case.

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“They should be able to enjoy meals out or holidays abroad together without worrying about an allergic reaction that could land them in hospital or worse.”

Palforzia decreases the severity of symptoms brought on by peanut allergies, including anaphylaxis / Credit: Flickr

In the UK, peanut allergies are currently said to affect one in 50 children.

The Artemis study, in particular, found that around six in 10 of the participants aged four to 17, who reacted to around 10mg of peanut protein at the start of the trial, were able to take a dose of 1,000mg by the end, which is well above the amount of accidental exposure.

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As mentionted, around 600 children aged four to 17 are expected to be treated with Palforzia this year, and the after that, some 2,000 children will be treated a year.

Professor George du Toit – Children’s Allergy Consultant at Evelina London – was senior investigator for the UK for both of the trials, and has called the rollout of the treatment “great news” for children and young people with peanut allergies.

“This will make a huge impact to the everyday lives of our patients and their families,” he added.

Featured Image – Flickr

News

Woman who protested alone outside Chanel show labelled ‘a queen’

Daisy Jackson Daisy Jackson A woman staged a lone protest outside the Chanel show

A woman who staged a lone protest outside the Chanel show in Manchester last week has been inundated with praise from locals.

The woman was positioned on High Street, mere metres from where a-list celebrities and high-fashion models were parading for the fashion giant.

The fact that the exclusive event took place in Manchester has been considered a huge coup for the city, and one which will have had a significant economic impact.

But the woman outside the Chanel show chose the opportunity to highlight the stark contrast between the luxurious fashion show and the harsh reality of many living in poverty in our city.

She held a sign that read: “Over 250,000 children living in poverty in Manchester. Higher than UK average.

“Manchester has one of the highest level of homelessness. 1 in 74 people. 7407 and rising!

“Where have you hidden the homeless Andy??”

Speaking about Chanel, she told photographer Project Certi: “No one was consulted about this. It’s not for the people of Manchester. You can come here if you want a celebrity spot but that’s not for you.

“This sort of thing moves around the world, they’ll have it somewhere weird and wonderful every year, and this is kind of like, capitalising on the working class history of Manchester.

“The poster’s got, ironically, the suffragettes on it, you know, people fighting for rights. They’re using images from the Hacienda, they’re using music of Joy Division and New Order, all of that what made Manchester on the music map all came out working class struggle. It all came during Thatcher and the attack on the working class, which is exactly what we’re seeing now with 12 years of austerity.”

@projectcerti

There was one woman on her own amongst the public. She was one person with a sign and i felt it was only right to amplify her voice. She makes some good points. #manchester #chanel #chanelshow #fyp #trending #people

♬ original sound – ᴘʀᴏᴊᴇᴄᴛ ᴄᴇʀᴛɪ

She also highlighted the man who died on the street in the Gay Village on a night where temperatures dropped, and the ‘cr*ppy B&Bs’ that homeless people find themselves housed in.

Speaking of the impact of Chanel on Manchester though, Deputy Leader Luthfur Rahman OBE said: “The impact of the decision by CHANEL to hold its prestigious Métiers d’Art show here in Manchester is something that is already resonating with people around the globe and is going to continue to be felt by the city for quite some time.

“It speaks volumes about the regard in which Manchester is already held across the world, but more importantly it also sends a clear signal to international businesses and the international visitor economy that Manchester is the place to be.

“It’s impossible at this stage to even begin to quantify the economic impact hosting the event has had on the city, or to put a figure on it. The true impact will involve not just the direct spend and income generated within the city over these last few weeks leading up to and during the event, but also the longer-term benefits that will come from the massive boost to Manchester’s profile that CHANEL has given the city, that in turn translates into more visitors coming to see what Manchester has to offer, and more businesses choosing to invest here.

“It has been without doubt quite a moment for Manchester, not least coming as it does off the back of many other significant moments for the city this year, that together place Manchester in absolute pole position on the world’s stage for the years ahead.”

In the comments on Project Certi’s video, one person wrote: “Thank you for giving this woman a platform.”

Another wrote: “Whoever this woman is, she’s a legend. As are you for capturing it.”

Someone else posted: “I have so much respect for this woman, I’d love to meet her and let her know she’s not alone in her feelings towards this.”

One comment said: “She is such a queen, bang on with everything she’s saying.”

And someone else called for ‘This lady for PM’.

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Featured image: TikTok, Project Certi

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Unexpected Manchester city centre street named ‘one of the most polluted’ in the UK

Clementine Hall Clementine Hall

A new fieldwork study has revealed the worst air polluted city centre streets in the UK, and a popular Manchester thoroughfare has been named one of the worst.

Except, it’s really not the street you’d expect it to be.

For some bizarre reason, despite the fact it’s a pedestrianised commercial shopping street in the heart of Manchester city centre, Market Street has been named one of the most polluted streets in the country.

Recordings were taken at high streets in the 25 largest towns and cities in the country over a two-week period, and the results found that 76% are exceeding the World Health Organisation’s (WHO) recommended annual level of air pollution, The Hoot reports.

The study enlisted a planning consultancy to collect samples using an air quality monitoring device at 11am on either a Tuesday, Wednesday, or Thursday to ensure as much comparability as possible between the locations.

Market Street has been named one of the ‘most polluted’ streets in the UK / David Dixon (via Geograph)

The study comes after a poll of 2,000 adults found that 36% have concerns over the health of the community due to air pollution, or the health of their family (26%) or themselves (25%).

Speaking on the shocking findings from the new study, Sam Clarke, who is the chief vehicle officer at the sustainable energy business, said: “With millions set to hit the high street this festive period, we wanted to look at the state of the nation’s air quality in the locations people will be doing most of their Christmas shopping.

“It’s shocking to see that so many were above the World Health Organisation’s annual recommendations for air pollution, and that one in 10 shoppers are even planning on foregoing the highstreets altogether due to air quality.”

20 streets in the UK were over the recommended World Health Organisation recommended levels of 5 µg/m3).

The Most-Polluted Streets in the UK

  1. Stoke-On-Trent (Parliament Street) – 11.7
  2. Newcastle (Northumberland Street) – 11.5
  3. Leicester (Gallowtree Gate) – 11.2
  4. Coventry (West Orchards Way) – 11.1
  5. Hull (Jameston Street) – 10.7
  6. Bradford (Broadway) – 10.6
  7. Southampton (Above Bar Street) – 8.8
  8. Nottingham (High Street) – 7.7
  9. Luton (George Street) – 7.6
  10. Manchester (Market Street) – 7.6
  11. Northampton (Abington Street) – 7.3
  12. Birmingham New Street – 7.3
  13. Liverpool (Church Street) – 7.1
  14. Derby (St Peter’s Street) – 6.9
  15. London (Oxford Street) – 6.8
  16. Sheffield (Fargate) – 6.3
  17. Brighton (Western Road) – 5.6
  18. Leeds (Briggate) – 5.3
  19. Portsmouth (Commercial Road) – 5.1

“If we’re to reach the World Health Organisation’s annual target of 5 µg/m3 of PM2.5 in our air, collectively we need to change our behaviours,” Sam Clarke added.

Read more:

“With vehicle emissions being a key contributor, anything we can do to travel more greenly, from walking more to cycling, and including electric vehicles, is a very valuable set forward to improve the air we breathe daily.”

Featured Image – Matt Taylor (via Flickr)

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