A Manchester man who was told he had just a year left to live has now been given the all-clear from cancer after a groundbreaking drug trial.
51-year-old Robert Glynn from Worsley in Salford is a massive Manchester United fan, enjoys playing snooker, golf, and fishing, and previously worked as a welder before his health turn a took and he went to his doctor with a severe pain in his shoulder that was preventing him from sleeping properly, and eventually developing an infection in his gall bladder.
After several scans and blood tests, Robert got the got the devastating news that he had intrahepatic bile duct cancer back in August 2020 – in the middle of the COVID-19 pandemic and the day before his 49th birthday.
Intrahepatic bile duct cancer – which is also known as biliary tract cancer – is a rare cancer that forms in the bile ducts inside the liver, with only around 1,000 people in the UK diagnosed with this type of disease each year, and only around 5% of people living for five years or more after diagnosis.
Sadly, not only is there a poor prognosis and few treatment options for this type of cancer, Robert’s cancer was at such an advanced stage that it was now in his liver and had spread to his adrenal gland too.
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So, he was referred to The Christie and offered the opportunity to participate in a clinical trial.
Robert Glynn from Manchester was given a year to live after being diagnosed with an aggressive form of cancer, but he is now disease-free thanks to a clinical trial at The Christie.
After showing an interest in taking part in the trial, Robert’s tumour sample was sent off for molecular analysis to check for any alterations, and it was found that his tumour had a high mutation burden – which means there was large numbers of genetic mutations in the cells – and this indicated that he may potentially have a good response to immunotherapy, which is a type of cancer treatment that helps the body’s immune system fight cancer.
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Based on these results, Robert was recommended to start a clinical trial with an immunotherapy drug already-approved for use in the UK, combined with the standard chemotherapy.
The treatment was administered intravenously.
The immunotherapy treatment together with chemotherapy proved so successful that it helped shrink the tumour in Robert’s liver and adrenal gland, and meant he was able to have surgery in April this year, which miraculously found only ‘dead tissue’ and showed that treatment combination killed-off all the cancer cells.
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Since the operation, Robert hasn’t needed any more treatment and his three-monthly scans show that he’s now clear of cancer.
Manchester man given a year to live now cancer-free after groundbreaking drug trial / Credit: The Christie NHS Foundation Trust
“I wouldn’t be here today without the trial,” Robert reflects.
“When I was given the option to take part in research, I jumped at the chance. You do anything you can to extend your life… and it’s important to remain positive and not give up. It’s never over until it’s over.”
Robert said getting the all-clear was “overwhelming”.
He continued: “In an odd kind of way having the diagnosis has turned my life around.
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“With my partner, Simone, we get out in nature and walk loads. When something like this happens you realise life is for living.”
Oncologists worldwide are now eagerly awaiting the results of the research into Robert’s case, as this, along with a further study with more patients, could lead to a change in the treatment of biliary tract cancer.
Featured Image – The Christie NHS Foundation Trust
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Extremely rare ‘dancing lemur’ that’s only the size of a tennis ball born at Chester Zoo
Emily Sergeant
An extremely rare ‘dancing lemur’ that weighs 100 grams and is only the size of a tennis ball has been born at Chester Zoo.
Primate conservationists at the UK’s largest charity zoo are celebrating the birth of the critically-endangered Coquerel’s sifaka – also known as a ‘dancing lemur’ – with the tiny baby arriving to parents Beatrice (12) and Elliot (12), and bringing an end to a five-month pregnancy.
The first images released by Chester Zoo show mum Beatrice carefully cradling her new baby, who was born with thick fuzzy white fur, as it clings to her belly.
Chester is the only zoo in the UK, and one of just three in Europe, to care for Coquerel’s sifakas.
Unlike other species of lemur, sifakas stand perfectly upright and use their powerful legs to spring side to side along the forest floor, hence them being affectionately nicknamed the ‘dancing lemur’.
ChDuke Lemur Centre in America to establish a conservation breeding programme across the continent that’s working to prevent the rare primates from becoming extinct.
The unique primates are found in only one place on Earth, the northwestern forests of Madagascar, where its wild population has declined by 80% in the last 30 years due to widespread deforestation, and as a result, the species has sadly been listed as the highest conservation priority there is – critically endangered.
Currently just nine sifaka reside in the whole of Europe, with four now found in Chester.
An extremely rare ‘dancing lemur’ that’s only the size of a tennis ball has been born at Chester Zoo / Credit: Chester Zoo
Chester Zoo has worked with the Duke Lemur Centre over in America to establish a conservation breeding programme across the continent that’s working to prevent the rare primates from becoming completely extinct.
Primate experts at the zoo say the new baby will begin to branch out and explore on its own at around six months old, and it’s at this point they’ll determine whether it’s a male or female.
“Every Coquerel’s sifaka birth is a huge cause for celebration,” commented Dr Nick Davis, who is the Mammals General Manager at Chester Zoo.
“There are very few remaining globally and every addition within the European conservation breeding programme is vital to the work we’re doing to safeguard the future of this species.
“The new baby has spent the first vital few weeks of life quietly bonding with mum, Beatrice, and we’re very happy to report that they’re both doing great so far. We’re seeing positive signs – they’ve been inseparable so far.”
Featured Image – Chester Zoo
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Police continue searches and issue public appeal to find missing Wigan man ‘known to many in the area’
Emily Sergeant
Officers are continuing searches to find missing Wigan man Darren Orme who’s said to be ‘known to many in the area’.
A public appeal for information has now been issued.
According to Greater Manchester Police (GMP), Darren was last seen shortly before 9pm last Wednesday (5 March) at the junction of Woodhouse Lane and Scot Lane Beech Hill Lane in Wigan, and officers have been searching several locations since he was reported missing the following day.
Darren is 54 years old, around 6ft 3in tall, and of slim build with short red/ginger hair.
He was last seen wearing blue jeans, blue trainers, a navy-blue Wigan Athletic jumper, and a three-quarter length blue Wigan Athletic jacket, police explained in their appeal.
Since Darren’s family reported him as missing, a large GMP response has been underway – including specialist search advisors, an underwater search team, and police dogs, alongside officers from Wigan Police Station.
If you have any information on Darren’s whereabouts, or you have any footage which may show Darren since he was reported missing, please call us on 101 quoting log 2423 of 06/03/2025. pic.twitter.com/5UCKtUYlmL
Darren’s family said in their own heartbreaking plea for him to return home that they ‘implore’ anyone who has any information to contact the police immediately and ‘help return Darren to us’.
Their direct appeal to Darren continues: “Darren, you’re not in any trouble. We just want you home. We need you to know that we love you and we’re here for you. Even though it may feel you have the world on your shoulders and you’re under a lot of stress, you’re not alone and the people of Wigan are right behind you.
“We will do anything we can to take this weight from you. We just want you safe, please come home to us.”
Detective Inspector Lee Shaw added: “Specialist officers from across the force are continuing to search for Darren… and we remain hopeful of finding [him] and want to retrace his last known movements.
“The number of people who have shared our appeals and are out looking for Darren shows how loved he is by the local community, and I would like to urge the public in continuing to share our appeals and information which may assist us.
“We know Darren is known to many in the area, and we appreciate all the help from people who have joined the search over the past few days.”
Anyone with any information on Darren’s potential whereabouts, or any footage which may have shown him since he was reported missing, are urged to call police on 101 quoting log 2423 of 06/03/2025.
Emily Sergeant -
30th December 2022 
