A Manchester man who was told he had just a year left to live has now been given the all-clear from cancer after a groundbreaking drug trial.
51-year-old Robert Glynn from Worsley in Salford is a massive Manchester United fan, enjoys playing snooker, golf, and fishing, and previously worked as a welder before his health turn a took and he went to his doctor with a severe pain in his shoulder that was preventing him from sleeping properly, and eventually developing an infection in his gall bladder.
After several scans and blood tests, Robert got the got the devastating news that he had intrahepatic bile duct cancer back in August 2020 – in the middle of the COVID-19 pandemic and the day before his 49th birthday.
Intrahepatic bile duct cancer – which is also known as biliary tract cancer – is a rare cancer that forms in the bile ducts inside the liver, with only around 1,000 people in the UK diagnosed with this type of disease each year, and only around 5% of people living for five years or more after diagnosis.
Sadly, not only is there a poor prognosis and few treatment options for this type of cancer, Robert’s cancer was at such an advanced stage that it was now in his liver and had spread to his adrenal gland too.
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So, he was referred to The Christie and offered the opportunity to participate in a clinical trial.
Robert Glynn from Manchester was given a year to live after being diagnosed with an aggressive form of cancer, but he is now disease-free thanks to a clinical trial at The Christie.
After showing an interest in taking part in the trial, Robert’s tumour sample was sent off for molecular analysis to check for any alterations, and it was found that his tumour had a high mutation burden – which means there was large numbers of genetic mutations in the cells – and this indicated that he may potentially have a good response to immunotherapy, which is a type of cancer treatment that helps the body’s immune system fight cancer.
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Based on these results, Robert was recommended to start a clinical trial with an immunotherapy drug already-approved for use in the UK, combined with the standard chemotherapy.
The treatment was administered intravenously.
The immunotherapy treatment together with chemotherapy proved so successful that it helped shrink the tumour in Robert’s liver and adrenal gland, and meant he was able to have surgery in April this year, which miraculously found only ‘dead tissue’ and showed that treatment combination killed-off all the cancer cells.
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Since the operation, Robert hasn’t needed any more treatment and his three-monthly scans show that he’s now clear of cancer.
Manchester man given a year to live now cancer-free after groundbreaking drug trial / Credit: The Christie NHS Foundation Trust
“I wouldn’t be here today without the trial,” Robert reflects.
“When I was given the option to take part in research, I jumped at the chance. You do anything you can to extend your life… and it’s important to remain positive and not give up. It’s never over until it’s over.”
Robert said getting the all-clear was “overwhelming”.
He continued: “In an odd kind of way having the diagnosis has turned my life around.
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“With my partner, Simone, we get out in nature and walk loads. When something like this happens you realise life is for living.”
Oncologists worldwide are now eagerly awaiting the results of the research into Robert’s case, as this, along with a further study with more patients, could lead to a change in the treatment of biliary tract cancer.
Featured Image – The Christie NHS Foundation Trust
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Four rare African ducklings have been hatched at Chester Zoo for the very first time
Danny Jones
More conversation celebration down the road at Chester Zoo, as the award-winning wildlife park has welcomed four African ducklings who belong to a rare breed.
As is so often the case with the work they do all year-round, their arrival could help signal the species’ survival in the long run, whose status was sadly upgraded from vulnerable to endangered on the official IUCN Red List.
The particular type of fowl we’re referring to is the Maccao duck, a stiff-tailed bird that typically belongs to the fresh and brackish inland waters of Eastern and Southern Africa.
Medium-sized, chunky, with big bills and subtle striping around their heads, they’re gorgeous creatures as is, but especially so as ducklings…
If you didn’t say ‘awww’ out loud, then you’re just lying.
As the Zoo itself put it, they are “rare, fluffy and VERY cute.” Celebrating what is “a breeding breakthrough for one of Africa’s rarest ducks […] so these little guys are kind of a big deal.”
These little delightful little duckies are known for diving down to the bottom of lakes and riverbeds to forage for aquatic invertebrates and plants; in fact, given the choice, they tend to prefer going underwater over flying pretty much full-stop.
As a resident species that doesn’t migrate like many other birds, they are native to nations like Namibia, Zimbabwe and Ethiopia. They’re identifiable by their dark black heads, blue bills (among the males, at least) and presence within the wetlands.
However, their estimated numbers continue to drop, and unfortunately, just 14 of their kind currently remain in Kenya and only 100 in Tanzania, with fewer than 5,000 believed to be left across the entire African continent.
Not only is this the first time the species has ever been successfully bred by bird experts at Chester Zoo, but conservationists hope ducklings will put a spotlight on the threatened species.
Their scientific name is ‘Oxyura maccoa’.Just like human babies, they prone to stuff all over their face.As far as ducklings go, these adorable little African variants are pretty special. (Credit: Supplied)
The zoo’s Head of Birds, Andrew Owen, said of their birth: “As one of just seven zoos in Europe – and 12 zoos globally – that care for Maccoa ducks, these ducklings are very special as they’re the first of their kind to ever hatch here at the zoo – making it a really historic moment for our team,
“This success gives a real boost to the future of the species, and these vital new additions will contribute to the safety-net population in zoos. These birds are facing rapid decline in the wild, so every hatchling really does count.
“To see them now out on the water inside our new Heart of Africa habitat, which is dedicated to helping Africa’s most threatened species thrive, makes this milestone even more special.”
Nothing short of brilliant news, we’re sure you’ll agree; better still, in addition to the crucially charitable and conversation-based tourist attraction being named one of England’s most popular destinations once again, but these are the only rare birds welcome by the zookeepers this month.
Vogue’s immersive ‘Inventing the Runway’ show is coming to Manchester
Thomas Melia
A Vogue immersive show titled ‘Inventing the Runway’ is coming to Manchester, and it’s even co-created by Anna Wintour herself.
Ever fancied learning more about the fashion world? Well, now’s your chance to hear everything you need to know from global fashion leaders and lifestyle magazine Vogue.
The Anna Wintour-approved immersive experience comes alongside the announcement of Factory International‘s Winter lineup, which features another new event all about voyaging to the moon.
This Vogue-fronted experience will incorporate interviews, visual media and more to help attendees visualise fashion shows of the past, present and future.
As well as understanding how fashion shows became the pinnacle of a designer’s vision, this runway-themed display also includes looking back at iconic moments of fashion and pop culture.
‘Inventing the Runway’ by Vogue is focusing on outfits worn by models and A-listers alike, with narration from the one and only Cate Blanchett.
You can expect to see curated pieces by significant creative minds in fashion history like Alexander McQueen, Balenciaga, Stella McCartney, Vivienne Westwood and lots more.
Throughout the Vogue experience, as well as coming visually face to face with fashion, you will also hear a soundscape that perfectly reflects this innovative industry with a fusion of classical and pop music.
This fashion exhibition uses the same Lightroom technology behind the impressive David Hockney experience that opened back in December.
Vogue is using this show to honour anyone who has made an impact in the fashion world.The Met Gala has become a staple in everyone’s calendar year in and year out.First Northern Quarter’s Chanel show, now this… Très chic. (Credit: Wikimedia Commons/GoodFon)
Anna Wintour, Chief Content Officer, Condé Nast, and Global Editorial Director, Vogue said: “At Vogue, we’ve been lucky enough over the decades to see many incredible runway shows, which have often told the story of fashion as much as the clothes themselves.”
“This Lightroom experience is a wonderful opportunity for a lot more people to experience first-hand the thrill of watching the history of fashion unfold right in front of them.”
You can experience Vogue’s ‘Inventing the Runway’ immersive show from 18 December to 10 January when it visits Aviva Studios this winter.
Find out more information and grab your tickets HERE.
Emily Sergeant -
30th December 2022 
