A Manchester man who was told he had just a year left to live has now been given the all-clear from cancer after a groundbreaking drug trial.
51-year-old Robert Glynn from Worsley in Salford is a massive Manchester United fan, enjoys playing snooker, golf, and fishing, and previously worked as a welder before his health turn a took and he went to his doctor with a severe pain in his shoulder that was preventing him from sleeping properly, and eventually developing an infection in his gall bladder.
After several scans and blood tests, Robert got the got the devastating news that he had intrahepatic bile duct cancer back in August 2020 – in the middle of the COVID-19 pandemic and the day before his 49th birthday.
Intrahepatic bile duct cancer – which is also known as biliary tract cancer – is a rare cancer that forms in the bile ducts inside the liver, with only around 1,000 people in the UK diagnosed with this type of disease each year, and only around 5% of people living for five years or more after diagnosis.
Sadly, not only is there a poor prognosis and few treatment options for this type of cancer, Robert’s cancer was at such an advanced stage that it was now in his liver and had spread to his adrenal gland too.
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So, he was referred to The Christie and offered the opportunity to participate in a clinical trial.
Robert Glynn from Manchester was given a year to live after being diagnosed with an aggressive form of cancer, but he is now disease-free thanks to a clinical trial at The Christie.
After showing an interest in taking part in the trial, Robert’s tumour sample was sent off for molecular analysis to check for any alterations, and it was found that his tumour had a high mutation burden – which means there was large numbers of genetic mutations in the cells – and this indicated that he may potentially have a good response to immunotherapy, which is a type of cancer treatment that helps the body’s immune system fight cancer.
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Based on these results, Robert was recommended to start a clinical trial with an immunotherapy drug already-approved for use in the UK, combined with the standard chemotherapy.
The treatment was administered intravenously.
The immunotherapy treatment together with chemotherapy proved so successful that it helped shrink the tumour in Robert’s liver and adrenal gland, and meant he was able to have surgery in April this year, which miraculously found only ‘dead tissue’ and showed that treatment combination killed-off all the cancer cells.
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Since the operation, Robert hasn’t needed any more treatment and his three-monthly scans show that he’s now clear of cancer.
Manchester man given a year to live now cancer-free after groundbreaking drug trial / Credit: The Christie NHS Foundation Trust
“I wouldn’t be here today without the trial,” Robert reflects.
“When I was given the option to take part in research, I jumped at the chance. You do anything you can to extend your life… and it’s important to remain positive and not give up. It’s never over until it’s over.”
Robert said getting the all-clear was “overwhelming”.
He continued: “In an odd kind of way having the diagnosis has turned my life around.
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“With my partner, Simone, we get out in nature and walk loads. When something like this happens you realise life is for living.”
Oncologists worldwide are now eagerly awaiting the results of the research into Robert’s case, as this, along with a further study with more patients, could lead to a change in the treatment of biliary tract cancer.
Featured Image – The Christie NHS Foundation Trust
News
The Stone Roses’ Gary ‘Mani’ Mounfield has died aged 63
Daisy Jackson
Tributes are pouring in for Gary ‘Mani’ Mounfield, after it was announced that the Stone Roses legend has died at the age of 63.
The bassist, who was also part of Primal Scream, was born in Crumpsall and has been one of Manchester’s most beloved musical figures ever since finding fame in the 1980s.
Mani’s brother Greg broke the news this afternoon, writing on Facebook: “IT IS WITH THE HEAVIEST OF HEARTS THAT I HAVE TO ANNOUNCE THE SAD PASSING OF MY BROTHER GARY MANI MOUNFIELD. RIP RKID.”
Mani’s wife Imelda also passed away in late 2023 after a battle with bowel cancer, for which the pair had raised money and awareness since her diagnosis.
That included a huge star-studded fundraising party where Mani and Imelda raised more than £100k for The Christie and local NHS charities.
Mani and Imelda shared twin sons, who were born in 2012.
Tributes are now flooding in for Mani, especially from those who have also been a part of the Manchester music scene.
Stone Roses frontman Ian Brown posted on X: “REST IN PEACE MANi X”
Rowetta shared a photo with Mani and Imelda and wrote: “Back with your Imelda, Mani. Going to miss you so much. All my love to the boys, the family & all those who knew & loved him.”
Tim Burgess of The Charlatans fame said: “I shared this photo a week or so ago on Mani’s birthday. It never failed to bring a smile to my face – and that was exactly the same for the man himself.
“One of the absolute best in every way – such a beautiful friend. Love you Mani x x. Never to be forgotten”
Shaun Ryder wrote: “RIP Mani – my heartfelt condolences to his twin boys and all of his family X”
Reverend and the Makers shared: “My heart is broken. Found out this morning and just felt low as it gets all day.
“Mani was my musical hero and just a lovely genuine human. When my Dad died , he offered me the warmest and best advice. No fuss, privately, straight up and always available to everyone.
“I’m a bit ill myself at the minute and not ashamed to say I shed at tear at the news. See on the next one mate.
“A true legend of the game. RIP”
Echo and the Bunnymen wrote: “I’m absolutely gutted to hear the news about Mani, who I have always loved and always will love, deeply and forever. Like a brother.
“I am in shock to be honest. Please tell me I’m just having a bad, bad dream. My thoughts and feelings and Mani, love to all of his family from me. Mac Bunnyman Xxx”
Featured image: Paul Husband
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Ticket touting officially banned to protect fans from rip-offs
Daisy Jackson
The government has officially banned ticket touting, making it illegal for tickets to be resold at inflated prices.
The new measures will destroy the operating model of ticket touts, who snap up tickets for theatre, sport and live music, then sell them on the secondary value for far more than their face value.
Oftentimes, touts use automated bots to buy large volumes of tickets at once, taking them away from real fans.
The government says it’s caused misery for millions of fans and damaged the live events industry.
But now, the practice is being banned, with the government making it illegal to sell tickets above face value (plus unavoidable fees like service charges).
Resale platforms will also have their service fees capped, and they’ll have a legal duty to monitor and enforce compliance with the price cap.
Individuals will also be banned from reselling more tickets than they were entitled to buy in the initial ticket sale.
Culture secretary Lisa Nandy said: “For too long, ticket touts have ripped off fans, using bots to snap up batches of tickets and resell them at sky-high prices. They’ve become a shadow industry on resale sites, acting without consequence.
“This government is putting fans first. Our new proposals will shut down the touts’ racket and make world-class music, comedy, theatre and sport affordable for everyone.”
Business Secretary Peter Kyle added: “The UK is home to a brilliant range of music, entertainers and sporting stars – but when fans are shut out – it only benefits the touts. That’s why we’re taking these bold measures to smash their model to pieces and make sure more fans can enjoy their favourite stars at a fair price.”
Dan Smith, lead singer of Bastille – who have been part of the campaign against ticket touting – said: “It’s such great news that the government has stepped up and introduced a price cap on resale tickets – something I’ve been campaigning for alongside O2 and the FanFair Alliance for a long time.
“It’s a good step towards protecting music fans from being ripped off and will allow more genuine fans to see their favourite artists perform at face value prices. I am welcoming a world where there are no more resellers snapping up all of the tickets and massively inflating their prices.”
According to analysis by the CMA, typical mark-ups on secondary market tickets exceed 50%, whilst investigations by Trading Standards has uncovered evidence of tickets being resold for up to six times their original cost.
It’s believed these new measures against ticket touts could save fans around £112 million annually, freeing up around 900,000 more tickets from the primary ticket sellers each year.
The use of strategies like dynamic pricing has also been a major source of frustration for fans – such as the method used during the Oasis reunion on-sale – and new rules mean that fans must be given 24 hours notice of tiered pricing, plus provide clearer price information during online queues.
Industry voices who have weight in today include Mumford & Sons, who said that touts have ‘taken advantage of the good will and passion of music fans for many years’; Ed Sheeran’s manager Stuart Camp, who said the announcement is ‘long overdue’; and Coldplay manager Phil Harvey, who added that the legislation will be ‘a game-changer’.
Emily Sergeant -
30th December 2022 
